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Kinome Profiling to Predict Sensitivity to MAPK Inhibition in Melanoma and to Provide New Insights into Intrinsic and Acquired Mechanism of Resistance Short Title: Sensitivity Prediction to MAPK Inhibitors in Melanoma

Kinome Profiling to Predict Sensitivity to MAPK Inhibition in Melanoma and to Provide New Insights into Intrinsic and Acquired Mechanism of Resistance Short Title: Sensitivity Prediction to MAPK Inhibitors in Melanoma

by Krayem, Mohamad, Aftimos, Philippe, Najem, Ahmad, van den Hooven, Tim, van den Berg, Adriënne, Hovestad-Bijl, Liesbeth, de Wijn, Rik, Hilhorst, Riet, Ruijtenbeek, Rob, Sabbah, Malak, Kerger, Joseph, Awada, Ahmad, Journe, Fabrice, Ghanem, Ghanem E
Published in Cancers (01.02.2020)

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Peptide microarrays for detailed, high-throughput substrate identification, kinetic characterization, and inhibition studies on protein kinase A

Peptide microarrays for detailed, high-throughput substrate identification, kinetic characterization, and inhibition studies on protein kinase A

by Hilhorst, Riet, Houkes, Liesbeth, van den Berg, Adriënne, Ruijtenbeek, Rob
Published in Analytical biochemistry (15.04.2009)

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Development of Selective Bisubstrate-Based Inhibitors Against Protein Kinase C (PKC) Isozymes By Using Dynamic Peptide Microarrays

Development of Selective Bisubstrate-Based Inhibitors Against Protein Kinase C (PKC) Isozymes By Using Dynamic Peptide Microarrays

by Poot, Alex J, van Ameijde, Jeroen, Slijper, Monique, van den Berg, Adriënne, Hilhorst, Riet, Ruijtenbeek, Rob, Rijkers, Dirk T.S, Liskamp, Rob M.J
Published in Chembiochem : a European journal of chemical biology (17.08.2009)

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Differentiating Benign from Malignant Thyroid Tumors by Kinase Activity Profiling and Dabrafenib BRAF V600E Targeting

Differentiating Benign from Malignant Thyroid Tumors by Kinase Activity Profiling and Dabrafenib BRAF V600E Targeting

by Hilhorst, Riet, van den Berg, Adrienne, Boender, Piet, van Wezel, Tom, Kievits, Tim, de Wijn, Rik, Ruijtenbeek, Rob, Corver, Willem E, Morreau, Hans
Published in Cancers (01.09.2023)

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Time dependent effect of cold ischemia on the phosphoproteome and protein kinase activity in fresh-frozen colorectal cancer tissue obtained from patients

Time dependent effect of cold ischemia on the phosphoproteome and protein kinase activity in fresh-frozen colorectal cancer tissue obtained from patients

by Buffart, Tineke E, van den Oord, Rosanne A H M, van den Berg, Adriënne, Hilhorst, Riet, Bastiaensen, Niek, Pruijt, Hans F M, van den Brule, Adriaan, Nooijen, Peet, Labots, Mariette, de Goeij-de Haas, Richard R, Dekker, Henk, Piersma, Sander R, Pham, Thang V, van der Leij, Theo, de Wijn, Rik, Ruijtenbeek, Rob, Jiménez, Connie R, Verheul, Henk M W
Published in Clinical proteomics (18.02.2021)

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Erratum: Krayem, M., et al. Kinome Profiling to Predict Sensitivity to MAPK Inhibition in Melanoma and to Provide New Insights into Intrinsic and Acquired Mechanism of Resistance Short Title: Sensitivity Prediction to MAPK Inhibitors in Melanoma. Cancers 2020, 12, 512

Erratum: Krayem, M., et al. Kinome Profiling to Predict Sensitivity to MAPK Inhibition in Melanoma and to Provide New Insights into Intrinsic and Acquired Mechanism of Resistance Short Title: Sensitivity Prediction to MAPK Inhibitors in Melanoma. Cancers 2020, 12, 512

by Krayem, Mohammad, Aftimos, Philippe, Najem, Ahmad, Hooven, Tim, Berg, Adriënne, Hovestad-Bijl, Liesbeth, Wijn, Rik, Hilhorst, Riet, Ruijtenbeek, Rob, Sabbah, Malak, Kerger, Joseph, Awada, Ahmad, Journe, Fabrice, Ghanem, Ghanem
Published in Cancers (14.10.2020)

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Identification of six novel WASP gene mutations in patients suffering from Wiskott-Aldrich syndrome

Identification of six novel WASP gene mutations in patients suffering from Wiskott-Aldrich syndrome

by Brooimans, Rik A., van den Berg, Adriënne J.A.M, Tamminga, Rienk Y.J., Revesz, Tom, Wulffraat, Nico M., Zegers, Ben J.M.
Published in Human mutation (01.04.2000)

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Correction: Krayem et al. Kinome Profiling to Predict Sensitivity to MAPK Inhibition in Melanoma and to Provide New Insights into Intrinsic and Acquired Mechanism of Resistance. Cancers 2020, 12, 512

Correction: Krayem et al. Kinome Profiling to Predict Sensitivity to MAPK Inhibition in Melanoma and to Provide New Insights into Intrinsic and Acquired Mechanism of Resistance. Cancers 2020, 12, 512

by Krayem, Mohammad, Aftimos, Philippe, Najem, Ahmad, van den Hooven, Tim, van den Berg, Adriënne, Hovestad-Bijl, Liesbeth, de Wijn, Rik, Hilhorst, Riet, Ruijtenbeek, Rob, Sabbah, Malak, Kerger, Joseph, Awada, Ahmad, Journe, Fabrice, Ghanem, Ghanem E
Published in Cancers (01.07.2024)

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Peptide microarrays for profiling of serine/threonine kinase activity of recombinant kinases and lysates of cells and tissue samples

Peptide microarrays for profiling of serine/threonine kinase activity of recombinant kinases and lysates of cells and tissue samples

by Hilhorst, Riet, Houkes, Liesbeth, Mommersteeg, Monique, Musch, Joyce, van den Berg, Adriënne, Ruijtenbeek, Rob
Published in Methods in molecular biology (Clifton, N.J.) (2013)

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Kinomic profiling of tumour xenografts derived from patients with non–small cell lung cancer confirms their fidelity and reveals potentially actionable pathways

Kinomic profiling of tumour xenografts derived from patients with non–small cell lung cancer confirms their fidelity and reveals potentially actionable pathways

by Tabbò, Fabrizio, Guerrera, Francesco, van den Berg, Adrienne, Gaudiano, Marcello, Maletta, Francesca, Bessone, Luca, Nottegar, Alessia, Costardi, Lorena, de Wijn, Rik, Ruijtenbeek, Rob, Delsedime, Luisa, Sapino, Anna, Ruffini, Enrico, Hilhorst, Riet, Inghirami, Giorgio
Published in European journal of cancer (1990) (01.02.2021)

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Abstract 3163: Discovery of a kinome signature predicting sensitivity and resistance to RAF-MAPK pathway inhibitors in melanoma

Abstract 3163: Discovery of a kinome signature predicting sensitivity and resistance to RAF-MAPK pathway inhibitors in melanoma

by Hilhorst, Riet, Krayem, Mohammed, Berg, Adrienne van den, Journe, Fabrice, Hovestad-Bijl, Liesbeth, Hooven, Tim van den, Wijn, Rik de, Aftimos, Philippe, Ghanem, Ghanem, Ruijtenbeek, Rob
Published in Cancer research (Chicago, Ill.) (01.07.2017)

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Abstract 2725: Kinase activity profiling combined with genotyping as a tool for predictive biomarker discovery for the treatment of gastroesophageal adenocarcinoma (GEC)

Abstract 2725: Kinase activity profiling combined with genotyping as a tool for predictive biomarker discovery for the treatment of gastroesophageal adenocarcinoma (GEC)

by Catenacci, Daniel V.T., Xu, Peng, Henderson, Les, Pijnenburg, Dirk, Berg, Adrienne van den, Ruijtenbeek, Rob
Published in Cancer research (Chicago, Ill.) (01.10.2014)

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Abstract 4322: Kinase activity profiles distinguish papillary thyroid cancers with and without BRAF V600E mutations

Abstract 4322: Kinase activity profiles distinguish papillary thyroid cancers with and without BRAF V600E mutations

by Hilhorst, Maria H., van den Berg, Adrienne, van Wezel, Tom, Kievits, Tim, Boender, Piet J., de Wijn, Rik, Ruijtenbeek, Rob, Corver, Wim, Morreau, Hans
Published in Cancer research (Chicago, Ill.) (01.08.2015)

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On-chip drug testing of an aggressive intra-abdominal variant of inflammatory myofibroblastic tumor by kinase activity profiling

On-chip drug testing of an aggressive intra-abdominal variant of inflammatory myofibroblastic tumor by kinase activity profiling

by Ruijtenbeek, Rob, van den Berg, Adrienne, Hilhorst, Riet, Kueffer, Stefan, Gaiter, Timo, Kievits, Tim, Ebert, Matthias
Published in Journal of clinical oncology (20.05.2013)

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Application of Kinase Activity Profiles to Predict Upcoming TKI Resistance In CML-Patients

Application of Kinase Activity Profiles to Predict Upcoming TKI Resistance In CML-Patients

by Boender, Piet, Janssen, Jeroen, Smit, Linda, Ruijtenbeek, Rob, Berg, Adrienne van den, Wijn, Rik de, Ossenkoppele, Gert J.
Published in Blood (19.11.2010)

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Revised exon-intron structure of human JAK3 locus

Revised exon-intron structure of human JAK3 locus

by Brooimans, R A, van der Slot, A J, van den Berg, A J, Zegers, B J
Published in European journal of human genetics : EJHG (01.10.1999)

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Kinome Profiling to Predict Sensitivity to MAPK Inhibition in Melanoma and to Provide New Insights into Intrinsic and Acquired Mechanism of Resistance

Kinome Profiling to Predict Sensitivity to MAPK Inhibition in Melanoma and to Provide New Insights into Intrinsic and Acquired Mechanism of Resistance

by Krayem, Mohammad, Aftimos, Philippe, Najem, Ahmad, van den Hooven, Tim, van den Berg, Adriënne, Hovestad-Bijl, Liesbeth, de Wijn, Rik, Hilhorst, Riet, Ruijtenbeek, Rob, Sabbah, Malak, Kerger, Joseph, Awada, Ahmad, Journe, Fabrice, Ghanem, Ghanem
Published in Cancers (22.02.2020)

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Kinome Profiling to Predict Sensitivity to MAPK Inhibition in Melanoma and to Provide New Insights into Intrinsic and Acquired Mechanism of ResistanceShort Title: Sensitivity Prediction to MAPK Inhibitors in Melanoma

Kinome Profiling to Predict Sensitivity to MAPK Inhibition in Melanoma and to Provide New Insights into Intrinsic and Acquired Mechanism of ResistanceShort Title: Sensitivity Prediction to MAPK Inhibitors in Melanoma

by Krayem, Mohamad, Aftimos, Philippe, Najem, Ahmad, van den Hooven, Tim, van den Berg, Adriënne, Hovestad-Bijl, Liesbeth, de Wijn, Rik, Hilhorst, Riet, Ruijtenbeek, Rob, Sabbah, Malak, Kerger, Joseph, Awada, Ahmad, Journe, Fabrice, Ghanem, Ghanem E
Published in Cancers (01.01.2020)

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Identification of novel Bruton's tyrosine kinase mutations in 10 unrelated subjects with X linked agammaglobulinaemia

Identification of novel Bruton's tyrosine kinase mutations in 10 unrelated subjects with X linked agammaglobulinaemia

by Brooimans, R A, van den Berg, A J, Rijkers, G T, Sanders, L A, van Amstel, J K, Tilanus, M G, Grubben, M J, Zegers, B J
Published in Journal of medical genetics (01.06.1997)

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