Stabilization of the Transcription Factor Foxp3 by the Deubiquitinase USP7 Increases Treg-Cell-Suppressive Capacity
van Loosdregt, Jorg, Fleskens, Veerle, Fu, Juan, Brenkman, Arjan B., Bekker, Cornelis P.J., Pals, Cornelieke E.G.M., Meerding, Jenny, Berkers, Celia R., Barbi, Joseph, Gröne, Andrea, Sijts, Alice J.A.M., Maurice, Madelon M., Kalkhoven, Eric, Prakken, Berent J., Ovaa, Huib, Pan, Fan, Zaiss, Dietmar M.W., Coffer, Paul J.
Published in Immunity (Cambridge, Mass.) (22.08.2013)
Published in Immunity (Cambridge, Mass.) (22.08.2013)
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Journal Article
Canonical Wnt Signaling Negatively Modulates Regulatory T Cell Function
van Loosdregt, Jorg, Fleskens, Veerle, Tiemessen, Machteld M., Mokry, Michal, van Boxtel, Ruben, Meerding, Jenny, Pals, Cornelieke E.G.M., Kurek, Dorota, Baert, Miranda R.M., Delemarre, Eveline M., Gröne, Andrea, Koerkamp, Marianne J.A. Groot, Sijts, Alice J.A.M., Nieuwenhuis, Edward E.S., Maurice, Madelon M., van Es, Johan H., ten Berge, Derk, Holstege, Frank C., Staal, Frank J.T., Zaiss, Dietmar M.W., Prakken, Berent J., Coffer, Paul J.
Published in Immunity (Cambridge, Mass.) (22.08.2013)
Published in Immunity (Cambridge, Mass.) (22.08.2013)
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Journal Article
Effectiveness of First‐Line Treatment With Recombinant Interleukin‐1 Receptor Antagonist in Steroid‐Naive Patients With New‐Onset Systemic Juvenile Idiopathic Arthritis: Results of a Prospective Cohort Study
Vastert, Sebastiaan J., Jager, Wilco, Noordman, Bo Jan, Holzinger, Dirk, Kuis, Wietse, Prakken, Berent J., Wulffraat, Nico M.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.04.2014)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.04.2014)
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Journal Article
Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization
van Loosdregt, Jorg, Vercoulen, Yvonne, Guichelaar, Teun, Gent, Yoony Y.J., Beekman, Jeffrey M., van Beekum, Olivier, Brenkman, Arjan B., Hijnen, Dirk-Jan, Mutis, Tuna, Kalkhoven, Eric, Prakken, Berent J., Coffer, Paul J.
Published in Blood (04.02.2010)
Published in Blood (04.02.2010)
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Journal Article
PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation
Petrelli, Alessandra, Mijnheer, Gerdien, Hoytema van Konijnenburg, David P, van der Wal, Maria M, Giovannone, Barbara, Mocholi, Enric, Vazirpanah, Nadia, Broen, Jasper C, Hijnen, Dirkjan, Oldenburg, Bas, Coffer, Paul J, Vastert, Sebastian J, Prakken, Berent J, Spierings, Eric, Pandit, Aridaman, Mokry, Michal, van Wijk, Femke
Published in The Journal of clinical investigation (01.10.2018)
Published in The Journal of clinical investigation (01.10.2018)
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Journal Article
Inhibition of Super-Enhancer Activity in Autoinflammatory Site-Derived T Cells Reduces Disease-Associated Gene Expression
Peeters, Janneke G.C., Vervoort, Stephin J., Tan, Sander C., Mijnheer, Gerdien, de Roock, Sytze, Vastert, Sebastiaan J., Nieuwenhuis, Edward E.S., van Wijk, Femke, Prakken, Berent J., Creyghton, Menno P., Coffer, Paul J., Mokry, Michal, van Loosdregt, Jorg
Published in Cell reports (Cambridge) (29.09.2015)
Published in Cell reports (Cambridge) (29.09.2015)
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Journal Article
Prerequisites for cytokine measurements in clinical trials with multiplex immunoassays
de Jager, Wilco, Bourcier, Katarzyna, Rijkers, Ger T, Prakken, Berent J, Seyfert-Margolis, Vicki
Published in BMC immunology (28.09.2009)
Published in BMC immunology (28.09.2009)
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Journal Article
T cells out of control—impaired immune regulation in the inflamed joint
Wehrens, Ellen J., Prakken, Berent J., van Wijk, Femke
Published in Nature reviews. Rheumatology (01.01.2013)
Published in Nature reviews. Rheumatology (01.01.2013)
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Journal Article
Histone Deacetylase Inhibitors Suppress Inflammatory Activation of Rheumatoid Arthritis Patient Synovial Macrophages and Tissue
Grabiec, Aleksander M, Krausz, Sarah, de Jager, Wilco, Burakowski, Tomasz, Groot, Dion, Sanders, Marjolein E, Prakken, Berent J, Maslinski, Wlodzimierz, Eldering, Eric, Tak, Paul P, Reedquist, Kris A
Published in The Journal of immunology (1950) (01.03.2010)
Published in The Journal of immunology (1950) (01.03.2010)
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Journal Article
How does age determine the development of human immune-mediated arthritis?
Degboe, Yannick, Vastert, Sebastiaan J., Prakken, Berent J., McInnes, Iain B.
Published in Nature reviews. Rheumatology (01.09.2022)
Published in Nature reviews. Rheumatology (01.09.2022)
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Journal Article
Autologous stem cell transplantation aids autoimmune patients by functional renewal and TCR diversification of regulatory T cells
Delemarre, Eveline M., van den Broek, Theo, Mijnheer, Gerdien, Meerding, Jenny, Wehrens, Ellen J., Olek, Sven, Boes, Marianne, van Herwijnen, Martijn J.C., Broere, Femke, van Royen, Annet, Wulffraat, Nico M., Prakken, Berent J., Spierings, Eric, van Wijk, Femke
Published in Blood (07.01.2016)
Published in Blood (07.01.2016)
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Journal Article
International online mentorship for translational researchers
Kools, Farah R W, Fox, Christine M, van Rijen, Harold V M, Prakken, Berent J
Published in BMC medical education (10.10.2024)
Published in BMC medical education (10.10.2024)
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Journal Article
Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells
Wehrens, Ellen J., Mijnheer, Gerdien, Duurland, Chantal L., Klein, Mark, Meerding, Jenny, van Loosdregt, Jorg, de Jager, Wilco, Sawitzki, Birgit, Coffer, Paul J., Vastert, Bas, Prakken, Berent J., van Wijk, Femke
Published in Blood (29.09.2011)
Published in Blood (29.09.2011)
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Journal Article
Hydroxychloroquine preferentially induces apoptosis of CD45RO+ effector T cells by inhibiting autophagy: A possible mechanism for therapeutic modulation of T cells
van Loosdregt, Jorg, PhD, Spreafico, Roberto, PhD, Rossetti, Maura, PhD, Prakken, Berent J., MD, PhD, Lotz, Martin, MD, PhD, Albani, Salvatore, MD, PhD
Published in Journal of allergy and clinical immunology (01.05.2013)
Published in Journal of allergy and clinical immunology (01.05.2013)
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Journal Article
Neonatal thymectomy reveals differentiation and plasticity within human naive T cells
van den Broek, Theo, Delemarre, Eveline M, Janssen, Willemijn J M, Nievelstein, Rutger A J, Broen, Jasper C, Tesselaar, Kiki, Borghans, Jose A M, Nieuwenhuis, Edward E S, Prakken, Berent J, Mokry, Michal, Jansen, Nicolaas J G, van Wijk, Femke
Published in The Journal of clinical investigation (01.03.2016)
Published in The Journal of clinical investigation (01.03.2016)
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Journal Article
How a four-year-old boy connects healthcare, biomedical research and undergraduate education
Drost, Rijkent H., Dictus, Wim J. A. G., Prakken, Berent J., Bovenschen, Niels
Published in Nature biotechnology (01.09.2019)
Published in Nature biotechnology (01.09.2019)
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Journal Article
Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis
Vastert, Sebastiaan J., van Wijk, Richard, D’Urbano, Leila E., de Vooght, Karen M. K., de Jager, Wilco, Ravelli, Angelo, Magni-Manzoni, Silvia, Insalaco, Antonella, Cortis, Elisabetta, van Solinge, Wouter W., Prakken, Berent J., Wulffraat, Nico M., de Benedetti, Fabrizio, Kuis, Wietse
Published in Rheumatology (Oxford, England) (01.03.2010)
Published in Rheumatology (Oxford, England) (01.03.2010)
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