The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection
Niu, Congrong, Livingston, Christine M, Li, Li, Beran, Rudolf K, Daffis, Stephane, Ramakrishnan, Dhivya, Burdette, Dara, Peiser, Leanne, Salas, Eduardo, Ramos, Hilario, Yu, Mei, Cheng, Guofeng, Strubin, Michel, Delaney, IV, William E, Fletcher, Simon P
Published in PloS one (17.01.2017)
Published in PloS one (17.01.2017)
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Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism
Niu, Congrong, Li, Li, Daffis, Stephane, Lucifora, Julie, Bonnin, Marc, Maadadi, Sarah, Salas, Eduardo, Chu, Ruth, Ramos, Hilario, Livingston, Christine M., Beran, Rudolf K., Garg, Abhishek V., Balsitis, Scott, Durantel, David, Zoulim, Fabien, Delaney, William E., Fletcher, Simon P.
Published in Journal of hepatology (01.05.2018)
Published in Journal of hepatology (01.05.2018)
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Spatiotemporal Analysis of Hepatitis B Virus X Protein in Primary Human Hepatocytes
Kornyeyev, Dmytro, Ramakrishnan, Dhivya, Voitenleitner, Christian, Livingston, Christine M, Xing, Weimei, Hung, Magdeleine, Kwon, Hyock Joo, Fletcher, Simon P, Beran, Rudolf K
Published in Journal of virology (15.08.2019)
Published in Journal of virology (15.08.2019)
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Hepatitis C Virus NS2 Protein Contributes to Virus Particle Assembly via Opposing Epistatic Interactions with the E1-E2 Glycoprotein and NS3-NS4A Enzyme Complexes
PHAN, Tung, BERAN, Rudolf K. F, PETERS, Christopher, LORENZ, Ivo C, LINDENBACH, Brett D
Published in Journal of Virology (01.09.2009)
Published in Journal of Virology (01.09.2009)
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RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP
DUMONT, Sophie, WEI CHENG, SEREBROV, Victor, BERAN, Rudolf K, TINOCO, Ignacio, PYLE, Anna Marie, BUSTAMANTE, Carlos
Published in Nature (05.01.2006)
Published in Nature (05.01.2006)
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In vitro resistance profile of hepatitis C virus NS5A inhibitor velpatasvir in genotypes 1 to 6
Dvory‐Sobol, Hadas, Han, Bin, Lu, Julia, Yu, Mei, Beran, Rudolf K., Cheng, Guofeng, Martin, Ross, Svarovskaia, Evguenia, Mo, Hongmei
Published in Journal of viral hepatitis (01.08.2019)
Published in Journal of viral hepatitis (01.08.2019)
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The NS4A Protein of Hepatitis C Virus Promotes RNA-Coupled ATP Hydrolysis by the NS3 Helicase
BERAN, Rudolf K. F, LINDENBACH, Brett D, PYLE, Anna Marie
Published in Journal of Virology (01.04.2009)
Published in Journal of Virology (01.04.2009)
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Identifying and Characterizing Interplay between Hepatitis B Virus X Protein and Smc5/6
Livingston, Christine M, Ramakrishnan, Dhivya, Strubin, Michel, Fletcher, Simon P, Beran, Rudolf K
Published in Viruses (03.04.2017)
Published in Viruses (03.04.2017)
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The C Terminus of Hepatitis C Virus NS4A Encodes an Electrostatic Switch That Regulates NS5A Hyperphosphorylation and Viral Replication
LINDENBACH, Brett D, PRAGAI, Béla M, MONTSERRET, Roland, BERAN, Rudolf K. F, PYLE, Anna M, PENIN, Francois, RICE, Charles M
Published in Journal of Virology (01.09.2007)
Published in Journal of Virology (01.09.2007)
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Physical and functional interactions among RNase E, polynucleotide phosphorylase and the cold‐shock protein, CsdA: evidence for a ‘cold shock degradosome’
Prud’homme‐Généreux, Annie, Beran, Rudolf K., Iost, Isabelle, Ramey, C. Shane, Mackie, George A., Simons, Robert W.
Published in Molecular microbiology (01.12.2004)
Published in Molecular microbiology (01.12.2004)
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A Small-Molecule Inhibitor of Hepatitis C Virus Infectivity
BUSH, Caroline O, POKROVSKII, Maria V, PAGRATIS, Nikos, WEIDONG ZHONG, DELANEY, William E, PAULSON, Matthew S, BERAN, Rudolf K. F, SAITO, Roland, MORGANELLI, Philip, CANALES, Eda, CLARKE, Michael O, LAZERWITH, Scott E, GOLDE, Justin, REID, Brian G, BABAOGLU, Kerim
Published in Antimicrobial Agents and Chemotherapy (01.01.2014)
Published in Antimicrobial Agents and Chemotherapy (01.01.2014)
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Establishing a Mechanistic Basis for the Large Kinetic Steps of the NS3 Helicase
Serebrov, Victor, Beran, Rudolf K.F., Pyle, Anna Marie
Published in The Journal of biological chemistry (23.01.2009)
Published in The Journal of biological chemistry (23.01.2009)
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Novel Mutations in a Tissue Culture-Adapted Hepatitis C Virus Strain Improve Infectious-Virus Stability and Markedly Enhance Infection Kinetics
POKROVSKII, Maria V, BUSH, Caroline O, PAULSON, Matthew S, BERAN, Rudolf K. F, ROBINSON, Margaret F, GUOFENG CHENG, TIRUNAGARI, Neeraj, FENAUX, Martijn, GREENSTEIN, Andrew E, WEIDONG ZHONG, DELANEY, William E
Published in Journal of Virology (01.04.2011)
Published in Journal of Virology (01.04.2011)
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Cellular growth kinetics distinguish a cyclophilin inhibitor from an HSP90 inhibitor as a selective inhibitor of hepatitis C virus
Beran, Rudolf K F, Sharma, Ruchi, Corsa, Amoreena C, Tian, Yang, Golde, Justin, Lundgaard, Greta, Delaney, 4th, William E, Zhong, Weidong, Greenstein, Andrew E
Published in PloS one (08.02.2012)
Published in PloS one (08.02.2012)
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Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor
Decorsière, Adrien, Mueller, Henrik, van Breugel, Pieter C., Abdul, Fabien, Gerossier, Laetitia, Beran, Rudolf K., Livingston, Christine M., Niu, Congrong, Fletcher, Simon P., Hantz, Olivier, Strubin, Michel
Published in Nature (London) (17.03.2016)
Published in Nature (London) (17.03.2016)
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Therapeutic shutdown of HBV transcripts promotes reappearance of the SMC5/6 complex and silencing of the viral genome in vivo
Allweiss, Lena, Giersch, Katja, Pirosu, Andrea, Volz, Tassilo, Muench, Robert C, Beran, Rudolf K, Urban, Stephan, Javanbakht, Hassan, Fletcher, Simon P, Lütgehetmann, Marc, Dandri, Maura
Published in Gut (01.02.2022)
Published in Gut (01.02.2022)
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