Mechanism of Secondary Nucleation at the Single Fibril Level from Direct Observations of Aβ42 Aggregation
Zimmermann, Manuela R, Bera, Subhas C, Meisl, Georg, Dasadhikari, Sourav, Ghosh, Shamasree, Linse, Sara, Garai, Kanchan, Knowles, Tuomas P. J
Published in Journal of the American Chemical Society (13.10.2021)
Published in Journal of the American Chemical Society (13.10.2021)
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Journal Article
Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective
Seifert, Mona, Bera, Subhas C, van Nies, Pauline, Kirchdoerfer, Robert N, Shannon, Ashleigh, Le, Thi-Tuyet-Nhung, Meng, Xiangzhi, Xia, Hongjie, Wood, James M, Harris, Lawrence D, Papini, Flavia S, Arnold, Jamie J, Almo, Steven, Grove, Tyler L, Shi, Pei-Yong, Xiang, Yan, Canard, Bruno, Depken, Martin, Cameron, Craig E, Dulin, David
Published in eLife (07.10.2021)
Published in eLife (07.10.2021)
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Journal Article
Mechanism of assembly of an elongation-competent SARS-CoV-2 replication transcription complex
Klein, Misha, Bera, Subhas C., Anderson, Thomas K., Wang, Bing, Papini, Flavia S., Arnold, Jamie J., Cameron, Craig E., Depken, Martin, Kirchdoerfer, Robert N., Artsimovitch, Irina, Dulin, David
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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Journal Article
Quantitative parameters of bacterial RNA polymerase open-complex formation, stabilization and disruption on a consensus promoter
Bera, Subhas C, America, Pim P B, Maatsola, Santeri, Seifert, Mona, Ostrofet, Eugeniu, Cnossen, Jelmer, Spermann, Monika, Papini, Flávia S, Depken, Martin, Malinen, Anssi M, Dulin, David
Published in Nucleic acids research (22.07.2022)
Published in Nucleic acids research (22.07.2022)
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Journal Article
A high-throughput correlative magnetic tweezers-TIRF assay to investigate protein-nucleic acids interactions
Feiz, M. Sadegh, Wubulikasimu, Yibulayin, Cnossen, Jelmer, Papini, Flavia Stal, Bera, Subhas C., Quack, Salina, Dulin, David
Published in Biophysical journal (08.02.2024)
Published in Biophysical journal (08.02.2024)
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Journal Article
Mechanism of secondary nucleation from the direct observation of Aβ42 aggregation at the single fibril level
Zimmermann, Manuela R., Bera, Subhas C., Meisl, Georg, Dasadhikari, Sourav, Ghosh, Shamasree, Linse, Sara, Garai, Kanchan, Knowles, Tuomas P.J.
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
Measurements of Aggregation Propensities of Amyloid Peptides by Real Time Monitoring of Growth of the Aggregates using Total Internal Reflection Fluorescence (TIRF) Microscopy
Bera, Subhas C., Ghosh, Shamasree, Baran Sil, Timir, Garai, Kanchan
Published in Biophysical journal (02.02.2018)
Published in Biophysical journal (02.02.2018)
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Journal Article
Direct observation of breathing dynamics at the mismatch induced DNA bubble with nanometre accuracy: a smFRET studyElectronic supplementary information (ESI) available: Materials and methods, sample preparation, data acquisition, data analysis and CD spectra, including two tables of calculated distances of the probable bubble shapes. See DOI: 10.1039/c6nr09348e
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Journal Article
Monovalent Salt Dependence of the Bacterial RNA Polymerase Open Complex Dynamics
Bera, Subhas C., Seifert, Mona, Ostrofet, Eugeniu, Spermann, Monika, Stal Papini, Flavia, Malinen, Anssi M., Dulin, David
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
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Journal Article
Direct observation of the external force mediated conformational dynamics of an IHF bound Holliday junctionElectronic supplementary information (ESI) available: The structure and sequence of 4WHJ, theory of smFRET-anisotropy calculation, schematic of smFRET-optical tweezers setup, and equations for the nonlinear dynamics. See DOI: 10.1039/c7fd00184c
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Journal Article
Quantitative parameters of bacterial RNA polymerase open-complex formation, stabilization and disruption on a consensus promoter
Bera, Subhas C, America, Pim P B, Maatsola, Santeri, Seifert, Mona, Ostrofet, Eugeniu, Cnossen, Jelmer, Spermann, Monika, Papini, Flavia S, Depken, Martin, Malinen, Anssi M, Dulin, David
Published in bioRxiv (13.10.2021)
Published in bioRxiv (13.10.2021)
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Paper
Signatures and mechanisms of efficacious therapeutic ribonucleotides against SARS-CoV-2 revealed by analysis of its replicase using magnetic tweezers
Seifert, Mona, Bera, Subhas C, Pauline Van Nies, Kirchdoerfer, Robert N, Shannon, Ashleigh, Le, Thi-Tuyet-Nhung, Grove, Tyler L, Papini, Flavia S, Arnold, Jamie J, Almo, Steven C, Canard, Bruno, Depken, Martin, Cameron, Craig E, Dulin, David
Published in bioRxiv (06.08.2020)
Published in bioRxiv (06.08.2020)
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Paper