Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis
Kiweler, Nicole, Delbrouck, Catherine, Pozdeev, Vitaly I., Neises, Laura, Soriano-Baguet, Leticia, Eiden, Kim, Xian, Feng, Benzarti, Mohaned, Haase, Lara, Koncina, Eric, Schmoetten, Maryse, Jaeger, Christian, Noman, Muhammad Zaeem, Vazquez, Alexei, Janji, Bassam, Dittmar, Gunnar, Brenner, Dirk, Letellier, Elisabeth, Meiser, Johannes
Published in Nature communications (16.05.2022)
Published in Nature communications (16.05.2022)
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Journal Article
Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions
Soriano-Baguet, Leticia, Grusdat, Melanie, Kurniawan, Henry, Benzarti, Mohaned, Binsfeld, Carole, Ewen, Anouk, Longworth, Joseph, Bonetti, Lynn, Guerra, Luana, Franchina, Davide G., Kobayashi, Takumi, Horkova, Veronika, Verschueren, Charlène, Helgueta, Sergio, Gérard, Deborah, More, Tushar H., Henne, Antonia, Dostert, Catherine, Farinelle, Sophie, Lesur, Antoine, Gérardy, Jean-Jacques, Jäger, Christian, Mittelbronn, Michel, Sinkkonen, Lasse, Hiller, Karsten, Meiser, Johannes, Brenner, Dirk
Published in Cell reports (Cambridge) (28.03.2023)
Published in Cell reports (Cambridge) (28.03.2023)
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Metabolic Potential of Cancer Cells in Context of the Metastatic Cascade
Benzarti, Mohaned, Delbrouck, Catherine, Neises, Laura, Kiweler, Nicole, Meiser, Johannes
Published in Cells (Basel, Switzerland) (05.09.2020)
Published in Cells (Basel, Switzerland) (05.09.2020)
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Journal Article
PKM2 diverts glycolytic flux in dependence on mitochondrial one-carbon cycle
Benzarti, Mohaned, Neises, Laura, Oudin, Anais, Krötz, Christina, Viry, Elodie, Gargiulo, Ernesto, Pulido, Coralie, Schmoetten, Maryse, Pozdeev, Vitaly, Lorenz, Nadia I., Ronellenfitsch, Michael W., Sumpton, David, Warmoes, Marc, Jaeger, Christian, Lesur, Antoine, Becker, Björn, Moussay, Etienne, Paggetti, Jerome, Niclou, Simone P., Letellier, Elisabeth, Meiser, Johannes
Published in Cell reports (Cambridge) (26.03.2024)
Published in Cell reports (Cambridge) (26.03.2024)
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S141: INHIBITION OF MYC TRANSLATION THROUGH TARGETING OF THE NEWLY IDENTIFIED PHB‐EIF4F COMPLEX AS THERAPEUTIC STRATEGY INCHRONIC LYMPHOCYTIC LEUKEMIA (CLL)
Largeot, Anne, Klapp, Vanessa, Viry, Elodie, Gonder, Susanne, Botana, Iria Fernandez, Blomme, Arnaud, Benzarti, Mohaned, Pierson, Sandrine, Duculty, Chloé, Marttila, Petra, Wierz, Marina, Gargiulo, Ernesto, Pagano, Giulia, An, Ning, El Hachem, Najla, Perez Hernandez, Daniel, Chakraborty, Supriya, Ysebaert, Loic, François, Jean‐Hugues, Cortez, Susan, Berchem, Guy, Efremov, Dimitar G, Dittmar, Gunnar, Szpakowska, Martyna, Chevigne, Andy, Nazarov, Petr V., Helleday, Thomas, Close, Pierre, Meiser, Johannes, Stamatopoulos, Basile, Désaubry, Laurent, Paggetti, Jérôme, Moussay, Etienne
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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Inhibition of MYC translation through targeting of the newly identified PHB-eIF4F complex as a therapeutic strategy in CLL
Largeot, Anne, Klapp, Vanessa, Viry, Elodie, Gonder, Susanne, Fernandez Botana, Iria, Blomme, Arnaud, Benzarti, Mohaned, Pierson, Sandrine, Duculty, Chloé, Marttila, Petra, Wierz, Marina, Gargiulo, Ernesto, Pagano, Giulia, An, Ning, El Hachem, Najla, Perez Hernandez, Daniel, Chakraborty, Supriya, Ysebaert, Loïc, François, Jean-Hugues, Cortez Clemente, Susan, Berchem, Guy, Efremov, Dimitar G., Dittmar, Gunnar, Szpakowska, Martyna, Chevigné, Andy, Nazarov, Petr V., Helleday, Thomas, Close, Pierre, Meiser, Johannes, Stamatopoulos, Basile, Désaubry, Laurent, Paggetti, Jérôme, Moussay, Etienne
Published in Blood (29.06.2023)
Published in Blood (29.06.2023)
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Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses
Gargiulo, Ernesto, Viry, Elodie, Morande, Pablo Elías, Largeot, Anne, Gonder, Susanne, Xian, Feng, Ioannou, Nikolaos, Benzarti, Mohaned, Kleine Borgmann, Felix Bruno, Mittelbronn, Michel, Dittmar, Gunnar, Nazarov, Petr V, Meiser, Johannes, Stamatopoulos, Basile, Ramsay, Alan G, Moussay, Etienne, Paggetti, Jérôme
Published in Blood cancer discovery (06.01.2023)
Published in Blood cancer discovery (06.01.2023)
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PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains T reg homeostasis during ageing
Danileviciute, Egle, Zeng, Ni, Capelle, Christophe M, Paczia, Nicole, Gillespie, Mark A, Kurniawan, Henry, Benzarti, Mohaned, Merz, Myriam P, Coowar, Djalil, Fritah, Sabrina, Vogt Weisenhorn, Daniela Maria, Gomez Giro, Gemma, Grusdat, Melanie, Baron, Alexandre, Guerin, Coralie, Franchina, Davide G, Léonard, Cathy, Domingues, Olivia, Delhalle, Sylvie, Wurst, Wolfgang, Turner, Jonathan D, Schwamborn, Jens Christian, Meiser, Johannes, Krüger, Rejko, Ranish, Jeff, Brenner, Dirk, Linster, Carole L, Balling, Rudi, Ollert, Markus, Hefeng, Feng Q
Published in Nature metabolism (26.05.2022)
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Published in Nature metabolism (26.05.2022)
Journal Article
Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis
Kiweler, Nicole, Delbrouck, Catherine, Pozdeev, Vitaly I, Neises, Laura, Soriano-Baguet, Leticia, Eiden, Kim, Feng Xian, Benzarti, Mohaned, Haase, Lara, Koncina, Eric, Schmoetten, Maryse, Jaeger, Christian, Muhammad, Zaeem Noman, Vazquez, Alexei, Janji, Bassam, Dittmar, Gunnar, Brenner, Dirk, Letellier, Elisabeth, Meiser, Johannes
Published in bioRxiv (14.03.2022)
Published in bioRxiv (14.03.2022)
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