Mutated and non‐mutated TP53 as targets in the treatment of leukaemia
Nahi, H., Selivanova, G., Lehmann, S., Möllgård, L., Bengtzen, S., Concha, H., Svensson, A., Wiman, K. G., Merup, M., Paul, C.
Published in British journal of haematology (01.05.2008)
Published in British journal of haematology (01.05.2008)
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Effects of PRIMA‐1 on chronic lymphocytic leukaemia cells with and without hemizygous p53 deletion
Nahi, H., Lehmann, S., Mollgard, L., Bengtzen, S., Selivanova, G., Wiman, K. G., Paul, C., Merup, M.
Published in British journal of haematology (01.11.2004)
Published in British journal of haematology (01.11.2004)
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PRIMA‐1 induces apoptosis in acute myeloid leukaemia cells with p53 gene deletion
Nahi, H., Merup, M., Lehmann, S., Bengtzen, S., Möllgård, L., Selivanova, G., Wiman, K. G., Paul, C.
Published in British journal of haematology (01.01.2006)
Published in British journal of haematology (01.01.2006)
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Bone marrow stroma cells derived from mononuclear cells at diagnosis as a source of germline control DNA for determination of somatic mutations in acute myeloid leukemia
Mujahed, H, Jansson, M, Bengtzén, S, Lehamnn, S
Published in Blood cancer journal (New York) (06.10.2017)
Published in Blood cancer journal (New York) (06.10.2017)
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Effects of arsenic trioxide (As2O3) on leukemic cells from patients with non‐M3 acute myelogenous leukemia: studies of cytotoxicity, apoptosis and the pattern of resistance
Lehmann, S., Bengtzen, S., Paul, A., Christensson, B., Paul, C.
Published in European journal of haematology (01.06.2001)
Published in European journal of haematology (01.06.2001)
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P543: TARGETING SAMHD1 WITH HYDROXYUREA IN FIRST‐LINE CYTARABINE‐BASED THERAPY OF NEWLY DIAGNOSED ACUTE MYELOID LEUKAEMIA: RESULTS FROM THE HEAT‐AML TRIAL
Jädersten, M., Lilienthal, I., Tsesmetzis, N., Lourda, M., Bengtzén, S., Bohlin, A., Arnroth, C., Erkers, T., Seashore‐Ludlow, B., Giraud, G., Barkhordar, G. S., Tao, S., Fogelstrand, L., Saft, L., Östling, P., Schinazi, R., Kim, B., Schaller, T., Juliusson, G., Deneberg, S., Lehmann, S., Rassidakis, G., Höglund, M., Henter, J.‐I., Herold, N.
Published in HemaSphere (01.06.2022)
Published in HemaSphere (01.06.2022)
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Comparison of Data from Fresh and Frozen AML Samples for Functional Drug Testing
Struyf, Nona, Arnroth, Cornelia, Sunandar, Stephanie, Bohlin, Anna, Bengtzén, Sofia, Lehmann, Sören, Kallioniemi, Olli, Östling, Päivi, Seashore-Ludlow, Brinton, Erkers, Tom
Published in BLOOD (15.11.2022)
Published in BLOOD (15.11.2022)
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Conference Proceeding
AML displays increased CTCF occupancy associated with aberrant gene expression and transcription factor binding
Mujahed, Huthayfa, Miliara, Sophia, Neddermeyer, Anne, Bengtzén, Sofia, Nilsson, Christer, Deneberg, Stefan, Cordeddu, Lina, Ekwall, Karl, Lennartsson, Andreas, Lehmann, Sören
Published in Blood (16.07.2020)
Published in Blood (16.07.2020)
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Data-Driven Molecular Hallmarks of Acute Myeloid Leukemia: Biological, Prognostic and Therapeutic Implications
Erkers, Tom, Marabita, Francesco, Struyf, Nona, Vesterlund, Mattias, James, Tojo, Arnroth, Cornelia, Bohlin, Anna, Bengtzén, Sofia, Österroos, Albin, Stahl, Matthias, Jafari, Rozbeh, Orre, Lukas, Pawitan, Yudi, Seashore-Ludlow, Brinton, Lehtiö, Janne, Lehmann, Sören, Östling, Päivi, Kallioniemi, Olli
Published in BLOOD (15.11.2022)
Published in BLOOD (15.11.2022)
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Conference Proceeding
Differential methylation in CN-AML preferentially targets non-CGI regions and is dictated by DNMT3A mutational status and associated with predominant hypomethylation of HOX genes
Qu, Ying, Lennartsson, Andreas, Gaidzik, Verena I, Deneberg, Stefan, Karimi, Mohsen, Bengtzén, Sofia, Höglund, Martin, Bullinger, Lars, Döhner, Konstanze, Lehmann, Sören
Published in Epigenetics (01.08.2014)
Published in Epigenetics (01.08.2014)
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Targeting SAMHD1 with hydroxyurea in first‐line cytarabine‐based therapy of newly diagnosed acute myeloid leukaemia: Results from the HEAT‐AML trial
Jädersten, Martin, Lilienthal, Ingrid, Tsesmetzis, Nikolaos, Lourda, Magda, Bengtzén, Sofia, Bohlin, Anna, Arnroth, Cornelia, Erkers, Tom, Seashore‐Ludlow, Brinton, Giraud, Géraldine, Barkhordar, Giti S., Tao, Sijia, Fogelstrand, Linda, Saft, Leonie, Östling, Päivi, Schinazi, Raymond F., Kim, Baek, Schaller, Torsten, Juliusson, Gunnar, Deneberg, Stefan, Lehmann, Sören, Rassidakis, Georgios Z., Höglund, Martin, Henter, Jan‐Inge, Herold, Nikolas
Published in Journal of internal medicine (01.12.2022)
Published in Journal of internal medicine (01.12.2022)
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Prognostic DNA methylation patterns in cytogenetically normal acute myeloid leukemia are predefined by stem cell chromatin marks
Deneberg, Stefan, Guardiola, Philippe, Lennartsson, Andreas, Qu, Ying, Gaidzik, Verena, Blanchet, Odile, Karimi, Mohsen, Bengtzén, Sofia, Nahi, Hareth, Uggla, Bertil, Tidefelt, Ulf, Höglund, Martin, Paul, Christer, Ekwall, Karl, Döhner, Konstanze, Lehmann, Sören
Published in Blood (17.11.2011)
Published in Blood (17.11.2011)
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microRNA-34b/c on chromosome 11q23 is aberrantly methylated in chronic lymphocytic leukemia
Deneberg, Stefan, Kanduri, Meena, Ali, Dina, Bengtzen, Sofia, Karimi, Mohsen, Qu, Ying, Kimby, Eva, Mansouri, Larry, Rosenquist, Richard, Lennartsson, Andreas, Lehmann, Sören
Published in Epigenetics (2014)
Published in Epigenetics (2014)
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APR-246 exhibits anti-leukemic activity and synergism with conventional chemotherapeutic drugs in acute myeloid leukemia cells
Ali, Dina, Jönsson-Videsäter, Kerstin, Deneberg, Stefan, Bengtzén, Sofia, Nahi, Hareth, Paul, Christer, Lehmann, Sören
Published in European journal of haematology (01.03.2011)
Published in European journal of haematology (01.03.2011)
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Challenging conventional karyotyping by next-generation karyotyping in 281 intensively treated patients with AML
Mareschal, Sylvain, Palau, Anna, Lindberg, Johan, Ruminy, Philippe, Nilsson, Christer, Bengtzén, Sofia, Engvall, Marie, Eriksson, Anna, Neddermeyer, Anne, Marchand, Vinciane, Jansson, Monika, Björklund, My, Jardin, Fabrice, Rantalainen, Mattias, Lennartsson, Andreas, Cavelier, Lucia, Grönberg, Henrik, Lehmann, Sören
Published in Blood advances (23.02.2021)
Published in Blood advances (23.02.2021)
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Delineating functional and molecular impact of ex vivo sample handling in precision medicine
Struyf, Nona, Österroos, Albin, Vesterlund, Mattias, Arnroth, Cornelia, James, Tojo, Sunandar, Stephanie, Mermelekas, Georgios, Bohlin, Anna, Hamberg Levedahl, Kerstin, Bengtzén, Sofia, Jafari, Rozbeh, Orre, Lukas M., Lehtiö, Janne, Lehmann, Sören, Östling, Päivi, Kallioniemi, Olli, Seashore-Ludlow, Brinton, Erkers, Tom
Published in NPJ precision oncology (19.02.2024)
Published in NPJ precision oncology (19.02.2024)
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The FLT3 inhibitor PKC412 in combination with cytostatic drugs in vitro in acute myeloid leukemia
Möllgård, Lars, Deneberg, Stefan, Nahi, Hareth, Bengtzen, Sofia, Jonsson-Videsäter, Kerstin, Fioretos, Thoas, Andersson, Anna, Paul, Christer, Lehmann, Sören
Published in Cancer chemotherapy and pharmacology (01.08.2008)
Published in Cancer chemotherapy and pharmacology (01.08.2008)
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Expression of p14ARF in De Novo AML with Normal Karyotype. Implication on Drug Resistance and Survival
Paul, Esbjorn O., Deneberg, Stefan, Lehmann, Soren, Bengtzén, Sofia, Nahi, Hareth
Published in BLOOD (16.11.2007)
Published in BLOOD (16.11.2007)
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Conference Proceeding