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Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts
Bortolomeazzi, Michele, Keddar, Mohamed Reda, Montorsi, Lucia, Acha-Sagredo, Amelia, Benedetti, Lorena, Temelkovski, Damjan, Choi, Subin, Petrov, Nedyalko, Todd, Katrina, Wai, Patty, Kohl, Johannes, Denner, Tamara, Nye, Emma, Goldstone, Robert, Ward, Sophia, Wilson, Gareth A., Al Bakir, Maise, Swanton, Charles, John, Susan, Miles, James, Larijani, Banafshe, Kunene, Victoria, Fontana, Elisa, Arkenau, Hendrik-Tobias, Parker, Peter J., Rodriguez-Justo, Manuel, Shiu, Kai-Keen, Spencer, Jo, Ciccarelli, Francesca D.
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2021)
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The inositol 5-phosphatase INPP5K participates in the fine control of ER organization
Dong, Rui, Zhu, Ting, Benedetti, Lorena, Gowrishankar, Swetha, Deng, Huichao, Cai, Yiying, Wang, Xiangming, Shen, Kang, De Camilli, Pietro
Published in The Journal of cell biology (01.10.2018)
Published in The Journal of cell biology (01.10.2018)
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Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis
Genet, Gael, Boyé, Kevin, Mathivet, Thomas, Ola, Roxana, Zhang, Feng, Dubrac, Alexandre, Li, Jinyu, Genet, Nafiisha, Henrique Geraldo, Luiz, Benedetti, Lorena, Künzel, Steffen, Pibouin-Fragner, Laurence, Thomas, Jean-Leon, Eichmann, Anne
Published in Nature communications (28.05.2019)
Published in Nature communications (28.05.2019)
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Patients with genetically heterogeneous synchronous colorectal cancer carry rare damaging germline mutations in immune-related genes
Cereda, Matteo, Gambardella, Gennaro, Benedetti, Lorena, Iannelli, Fabio, Patel, Dominic, Basso, Gianluca, Guerra, Rosalinda F., Mourikis, Thanos P., Puccio, Ignazio, Sinha, Shruti, Laghi, Luigi, Spencer, Jo, Rodriguez-Justo, Manuel, Ciccarelli, Francesca D.
Published in Nature communications (05.07.2016)
Published in Nature communications (05.07.2016)
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The role of the matricellular protein SPARC in the dynamic interaction between the tumor and the host
Podhajcer, Osvaldo L., Benedetti, Lorena, Girotti, Maria Romina, Prada, Federico, Salvatierra, Edgardo, Llera, Andrea S.
Published in Cancer and metastasis reviews (01.09.2008)
Published in Cancer and metastasis reviews (01.09.2008)
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YAP1 nuclear efflux and transcriptional reprograming follow membrane diminution upon VSV-G-induced cell fusion
Feliciano, Daniel, Ott, Carolyn M., Espinosa-Medina, Isabel, Weigel, Aubrey V., Benedetti, Lorena, Milano, Kristin M., Tang, Zhonghua, Lee, Tzumin, Kliman, Harvey J., Guller, Seth M., Lippincott-Schwartz, Jennifer
Published in Nature communications (23.07.2021)
Published in Nature communications (23.07.2021)
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CRISPR/Cas9 editing reveals novel mechanisms of clustered microRNA regulation and function
Lataniotis, Lazaros, Albrecht, Andreas, Kok, Fatma O., Monfries, Clinton A. L., Benedetti, Lorena, Lawson, Nathan D., Hughes, Simon M., Steinhofel, Kathleen, Mayr, Manuel, Zampetaki, Anna
Published in Scientific reports (17.08.2017)
Published in Scientific reports (17.08.2017)
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Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation
Barrio-Real, Laura, Benedetti, Lorena G, Engel, Nora, Tu, Yaping, Cho, Soonweng, Sukumar, Saraswati, Kazanietz, Marcelo G
Published in Breast cancer research : BCR (24.09.2014)
Published in Breast cancer research : BCR (24.09.2014)
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Epilepsy and intellectual disability linked protein Shrm4 interaction with GABABRs shapes inhibitory neurotransmission
Zapata, Jonathan, Moretto, Edoardo, Hannan, Saad, Murru, Luca, Longatti, Anna, Mazza, Davide, Benedetti, Lorena, Fossati, Matteo, Heise, Christopher, Ponzoni, Luisa, Valnegri, Pamela, Braida, Daniela, Sala, Mariaelvina, Francolini, Maura, Hildebrand, Jeffrey, Kalscheuer, Vera, Fanelli, Francesca, Sala, Carlo, Bettler, Bernhard, Bassani, Silvia, Smart, Trevor G., Passafaro, Maria
Published in Nature communications (06.03.2017)
Published in Nature communications (06.03.2017)
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SPARC Promotes Cathepsin B-Mediated Melanoma Invasiveness through a Collagen I/α2β1 Integrin Axis
Girotti, María R., Fernández, Marisol, López, Juan A., Camafeita, Emilio, Fernández, Elmer A., Albar, Juan P., Benedetti, Lorena G., Valacco, María P., Brekken, Rolf A., Podhajcer, Osvaldo L., Llera, Andrea S.
Published in Journal of investigative dermatology (01.12.2011)
Published in Journal of investigative dermatology (01.12.2011)
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INaP selective inhibition reverts precocious inter- and motorneurons hyperexcitability in the Sod1-G93R zebrafish ALS model
Benedetti, Lorena, Ghilardi, Anna, Rottoli, Elsa, De Maglie, Marcella, Prosperi, Laura, Perego, Carla, Baruscotti, Mirko, Bucchi, Annalisa, Del Giacco, Luca, Francolini, Maura
Published in Scientific reports (15.04.2016)
Published in Scientific reports (15.04.2016)
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Predictive Outcomes for HER2-enriched Cancer Using Growth and Metastasis Signatures Driven By SPARC
Güttlein, Leandro N., Benedetti, Lorena G., Fresno, Cristóbal, Spallanzani, Raúl G., Mansilla, Sabrina F., Rotondaro, Cecilia, Raffo Iraolagoitia, Ximena L., Salvatierra, Edgardo, Bravo, Alicia I., Fernández, Elmer A., Gottifredi, Vanesa, Zwirner, Norberto W., Llera, Andrea S., Podhajcer, Osvaldo L.
Published in Molecular cancer research (01.03.2017)
Published in Molecular cancer research (01.03.2017)
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Abstract 4140: Secreted protein acidic and rich in cysteine (SPARC) promotes mammary tumor growth and dissemination through immune and non-immune mediated mechanisms
Güttlein, Leandro N., Benedetti, Lorena G., Spallanzani, Raúl G., Rotondaro, Cecilia, Raffo Iraolagoitia, Ximena L., Sganga, Leonardo, Salvatierra, Edgardo, Llera, Andrea S., Zwirner, Norberto W., Podhajcer, Osvaldo L.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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SPARC Endogenous Level, rather than Fibroblast-Produced SPARC or Stroma Reorganization Induced by SPARC, Is Responsible for Melanoma Cell Growth
Prada, Federico, Benedetti, Lorena G., Bravo, Alicia I., Alvarez, Mariano J., Carbone, Cecilia, Podhajcer, Osvaldo L.
Published in Journal of investigative dermatology (01.11.2007)
Published in Journal of investigative dermatology (01.11.2007)
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ICln: A New Regulator of Non-Erythroid 4.1R Localisation and Function
Bazzini, Claudia, Benedetti, Lorena, Civello, Davide, Zanoni, Chiara, Rossetti, Valeria, Marchesi, Davide, Garavaglia, Maria Lisa, Paulmichl, Markus, Francolini, Maura, Meyer, Giuliano, Rodighiero, Simona
Published in PloS one (08.10.2014)
Published in PloS one (08.10.2014)
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The role of the matricellular protein SPARC in the dynamic interaction between the tumor and the host
Podhajcer, Osvaldo L., Benedetti, Lorena Gabriela, Girotti, Maria Romina, Prada, Federico, Salvatierra, Edgardo, Llera, Andrea S.
Published in Cancer and metastasis reviews (01.12.2008)
Published in Cancer and metastasis reviews (01.12.2008)
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