Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancers
Scheper, Wouter, Kelderman, Sander, Fanchi, Lorenzo F, Linnemann, Carsten, Bendle, Gavin, de Rooij, Marije A J, Hirt, Christian, Mezzadra, Riccardo, Slagter, Maarten, Dijkstra, Krijn, Kluin, Roelof J C, Snaebjornsson, Petur, Milne, Katy, Nelson, Brad H, Zijlmans, Henry, Kenter, Gemma, Voest, Emile E, Haanen, John B A G, Schumacher, Ton N
Published in Nature medicine (01.01.2019)
Published in Nature medicine (01.01.2019)
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Journal Article
RNAi-mediated TCR Knockdown Prevents Autoimmunity in Mice Caused by Mixed TCR Dimers Following TCR Gene Transfer
Bunse, Mario, Bendle, Gavin M, Linnemann, Carsten, Bies, Laura, Schulz, Stephan, Schumacher, Ton N, Uckert, Wolfgang
Published in Molecular therapy (01.11.2014)
Published in Molecular therapy (01.11.2014)
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Journal Article
Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritis
Wright, Graham P, Notley, Clare A, Xue, Shao-An, Bendle, Gavin M, Holler, Angelika, Schumacher, Ton N, Ehrenstein, Michael R, Stauss, Hans J
Published in Proceedings of the National Academy of Sciences - PNAS (10.11.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (10.11.2009)
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Journal Article
Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy
de Witte, Moniek A, Uckert, Wolfgang, Song, Ji-Ying, Linnemann, Carsten, Haanen, John B A G, Bendle, Gavin M, Schumacher, Ton N M, Pouw, Nadine, Kaiser, Andrew D M, Hooijkaas, Anna I, Bies, Laura, Jorritsma, Annelies, Debets, Reno, Kieback, Elisa
Published in Nature medicine (01.05.2010)
Published in Nature medicine (01.05.2010)
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Journal Article
Safety and efficacy of Tet-regulated IL-12 expression in cancer-specific T cells
Alsaieedi, Ahdab, Holler, Angelika, Velica, Pedro, Bendle, Gavin, Stauss, Hans J.
Published in Oncoimmunology (04.03.2019)
Published in Oncoimmunology (04.03.2019)
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Journal Article
High-throughput identification of antigen-specific TCRs by TCR gene capture
Linnemann, Carsten, Heemskerk, Bianca, Kvistborg, Pia, Kluin, Roelof J C, Bolotin, Dmitriy A, Chen, Xiaojing, Bresser, Kaspar, Nieuwland, Marja, Schotte, Remko, Michels, Samira, Gomez-Eerland, Raquel, Jahn, Lorenz, Hombrink, Pleun, Legrand, Nicolas, Shu, Chengyi Jenny, Mamedov, Ilgar Z, Velds, Arno, Blank, Christian U, Haanen, John B A G, Turchaninova, Maria A, Kerkhoven, Ron M, Spits, Hergen, Hadrup, Sine Reker, Heemskerk, Mirjam H M, Blankenstein, Thomas, Chudakov, Dmitriy M, Bendle, Gavin M, Schumacher, Ton N M
Published in Nature medicine (01.11.2013)
Published in Nature medicine (01.11.2013)
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Journal Article
Blockade of TGF-β signaling greatly enhances the efficacy of TCR gene therapy of cancer
Bendle, Gavin M, Linnemann, Carsten, Bies, Laura, Song, Ji-Ying, Schumacher, Ton N M
Published in The Journal of immunology (1950) (15.09.2013)
Published in The Journal of immunology (1950) (15.09.2013)
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Journal Article
T-Cell Receptor Gene Therapy: Critical Parameters for Clinical Success
Linnemann, Carsten, Schumacher, Ton N.M., Bendle, Gavin M.
Published in Journal of investigative dermatology (01.09.2011)
Published in Journal of investigative dermatology (01.09.2011)
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Journal Article
Isolation of T cell receptors targeting recurrent neoantigens in hematological malignancies
Tubb, Vanessa M, Schrikkema, Deborah S, Croft, Nathan P, Purcell, Anthony W, Linnemann, Carsten, Freriks, Manon R, Chen, Frederick, Long, Heather M, Lee, Steven P, Bendle, Gavin M
Published in Journal for immunotherapy of cancer (13.07.2018)
Published in Journal for immunotherapy of cancer (13.07.2018)
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Journal Article
A Critical Role of T Cell Antigen Receptor-Transduced MHC Class I-Restricted Helper T Cells in Tumor Protection
Morris, Emma C., Tsallios, Aristotle, Bendle, Gavin M., Xue, Shao-an, Stauss, Hans J., Mitchison, N. Avrion
Published in Proceedings of the National Academy of Sciences - PNAS (31.05.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (31.05.2005)
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Journal Article
Preclinical development of T cell receptor gene therapy
Bendle, Gavin M, Haanen, John BAG, Schumacher, Ton NM
Published in Current opinion in immunology (01.04.2009)
Published in Current opinion in immunology (01.04.2009)
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Journal Article
Tracer-cocktail injections for combined pre- and intraoperative multimodal imaging of lymph nodes in a spontaneous mouse prostate tumor model
van Leeuwen, Anne C, Buckle, Tessa, Bendle, Gavin, Vermeeren, Lenka, Olmos, Renato V, van de Poel, Henk G, van Leeuwen, Fijs W. B
Published in Journal of Biomedical Optics (01.01.2011)
Published in Journal of Biomedical Optics (01.01.2011)
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Journal Article
Requirements for Effective Antitumor Responses of TCR Transduced T Cells
de Witte, Moniek A, Jorritsma, Annelies, Kaiser, Andrew, van den Boom, Marly D, Dokter, Maarten, Bendle, Gavin M, Haanen, John B. A. G, Schumacher, Ton N. M
Published in The Journal of immunology (1950) (01.10.2008)
Published in The Journal of immunology (1950) (01.10.2008)
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Journal Article
TCR Gene Therapy of Spontaneous Prostate Carcinoma Requires In Vivo T Cell Activation
de Witte, Moniek A, Bendle, Gavin M, van den Boom, Marly D, Coccoris, Miriam, Schell, Todd D, Tevethia, Satvir S, van Tinteren, Harm, Mesman, Elly M, Song, Ji-Ying, Schumacher, Ton N. M
Published in The Journal of immunology (1950) (15.08.2008)
Published in The Journal of immunology (1950) (15.08.2008)
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Journal Article
Induction of unresponsiveness limits tumor protection by adoptively transferred MDM2-specific cytotoxic T lymphocytes
BENDLE, Gavin M, HOLLER, Angelika, PANG, Luke-Kwok, HSU, Stephen, KRAMPERA, Mauro, SIMPSON, Elizabeth, STAUSS, Hans J
Published in Cancer research (Chicago, Ill.) (01.11.2004)
Published in Cancer research (Chicago, Ill.) (01.11.2004)
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Journal Article
Neuroblastoma Arginase Activity Creates an Immunosuppressive Microenvironment That Impairs Autologous and Engineered Immunity
Mussai, Francis, Egan, Sharon, Hunter, Stuart, Webber, Hannah, Fisher, Jonathan, Wheat, Rachel, McConville, Carmel, Sbirkov, Yordan, Wheeler, Kate, Bendle, Gavin, Petrie, Kevin, Anderson, John, Chesler, Louis, De Santo, Carmela
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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