An Activity-Based Probe for Cathepsin K Imaging with Excellent Potency and Selectivity
Lemke, Carina, Benýšek, Jakub, Brajtenbach, Dominik, Breuer, Christian, Jílková, Adéla, Horn, Martin, Buša, Michal, Ulrychová, Lenka, Illies, Annika, Kubatzky, Katharina F, Bartz, Ulrike, Mareš, Michael, Gütschow, Michael
Published in Journal of medicinal chemistry (23.09.2021)
Published in Journal of medicinal chemistry (23.09.2021)
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Journal Article
Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes
Benýšek, Jakub, Buša, Michal, Rubešová, Petra, Fanfrlík, Jindřich, Lepšík, Martin, Brynda, Jiří, Matoušková, Zuzana, Bartz, Ulrike, Horn, Martin, Gütschow, Michael, Mareš, Michael
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
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Journal Article
1,2,4-Thiadiazole acyclic nucleoside phosphonates as inhibitors of cysteine dependent enzymes cathepsin K and GSK-3β
Pomeislová, Alice, Otmar, Miroslav, Rubešová, Petra, Benýšek, Jakub, Matoušová, Marika, Mertlíková-Kaiserová, Helena, Pohl, Radek, Poštová Slavětínská, Lenka, Pomeisl, Karel, Krečmerová, Marcela
Published in Bioorganic & medicinal chemistry (15.02.2021)
Published in Bioorganic & medicinal chemistry (15.02.2021)
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