GhostKnockoff inference empowers identification of putative causal variants in genome-wide association studies
He, Zihuai, Liu, Linxi, Belloy, Michael E, Le Guen, Yann, Sossin, Aaron, Liu, Xiaoxia, Qi, Xinran, Ma, Shiyang, Gyawali, Prashnna K, Wyss-Coray, Tony, Tang, Hua, Sabatti, Chiara, Candès, Emmanuel, Greicius, Michael D, Ionita-Laza, Iuliana
Published in Nature communications (23.11.2022)
Published in Nature communications (23.11.2022)
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Journal Article
Common X‐Chromosome Variants Are Associated with Parkinson Disease Risk
Le Guen, Yann, Napolioni, Valerio, Belloy, Michael E., Yu, Eric, Krohn, Lynne, Ruskey, Jennifer A., Gan‐Or, Ziv, Kennedy, Gabriel, Eger, Sarah J., Greicius, Michael D.
Published in Annals of neurology (01.07.2021)
Published in Annals of neurology (01.07.2021)
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Journal Article
Sex- and APOE-specific genetic risk factors for late-onset Alzheimer's disease: Evidence from gene-gene interaction of longevity-related loci
Dato, Serena, De Rango, Francesco, Crocco, Paolina, Pallotti, Stefano, Belloy, Michael E, Le Guen, Yann, Greicius, Michael D, Passarino, Giuseppe, Rose, Giuseppina, Napolioni, Valerio
Published in Aging cell (01.09.2023)
Published in Aging cell (01.09.2023)
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Journal Article
APOE effects on regional tau in preclinical Alzheimer's disease
Young, Christina B, Johns, Emily, Kennedy, Gabriel, Belloy, Michael E, Insel, Philip S, Greicius, Michael D, Sperling, Reisa A, Johnson, Keith A, Poston, Kathleen L, Mormino, Elizabeth C
Published in Molecular neurodegeneration (04.01.2023)
Published in Molecular neurodegeneration (04.01.2023)
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Journal Article
Association of African Ancestry–Specific APOE Missense Variant R145C With Risk of Alzheimer Disease
Le Guen, Yann, Raulin, Ana-Caroline, Logue, Mark W, Sherva, Richard, Belloy, Michael E, Eger, Sarah J, Chen, Annabel, Kennedy, Gabriel, Kuchenbecker, Lindsey, O’Leary, Justin P, Zhang, Rui, Merritt, Victoria C, Panizzon, Matthew S, Hauger, Richard L, Gaziano, J. Michael, Bu, Guojun, Thornton, Timothy A, Farrer, Lindsay A, Napolioni, Valerio, He, Zihuai, Greicius, Michael D
Published in JAMA : the journal of the American Medical Association (21.02.2023)
Published in JAMA : the journal of the American Medical Association (21.02.2023)
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Journal Article
APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer’s disease pathology
Chemparathy, Augustine, Le Guen, Yann, Chen, Sunny, Lee, Eun-Gyung, Leong, Lesley, Gorzynski, John E., Jensen, Tanner D., Ferrasse, Alexis, Xu, Guangxue, Xiang, Hong, Belloy, Michael E., Kasireddy, Nandita, Peña-Tauber, Andrés, Williams, Kennedy, Stewart, Ilaria, Talozzi, Lia, Wingo, Thomas S., Lah, James J., Jayadev, Suman, Hales, Chadwick M., Peskind, Elaine, Child, Daniel D., Roeber, Sigrun, Keene, C. Dirk, Cong, Le, Ashley, Euan A., Yu, Chang-En, Greicius, Michael D.
Published in Neuron (Cambridge, Mass.) (03.04.2024)
Published in Neuron (Cambridge, Mass.) (03.04.2024)
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Journal Article
Genome-wide analysis of common and rare variants via multiple knockoffs at biobank scale, with an application to Alzheimer disease genetics
He, Zihuai, Le Guen, Yann, Liu, Linxi, Lee, Justin, Ma, Shiyang, Yang, Andrew C., Liu, Xiaoxia, Rutledge, Jarod, Losada, Patricia Moran, Song, Bowen, Belloy, Michael E., Butler, Robert R., Longo, Frank M., Tang, Hua, Mormino, Elizabeth C., Wyss-Coray, Tony, Greicius, Michael D., Ionita-Laza, Iuliana
Published in American journal of human genetics (02.12.2021)
Published in American journal of human genetics (02.12.2021)
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Journal Article
Sex‐heterogenous effect on Alzheimer’s disease risk at the BIN1 locus
Guen, Yann Le, Eger, Sarah J, Belloy, Michael E, Kennedy, Gabriel, He, Zihuai, Napolioni, Valerio, Greicius, Michael D
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
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Journal Article
Rare TBK1 variant may confer protection in an APOE4+ family
Eger, Sarah J, Guen, Yann Le, Belloy, Michael E, Napolioni, Valerio, Greicius, Michael D
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
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Journal Article
Long-term ovarian hormone deprivation alters functional connectivity, brain neurochemical profile and white matter integrity in the Tg2576 amyloid mouse model of Alzheimer's disease
Kara, Firat, Belloy, Michael E., Voncken, Rick, Sarwari, Zahra, Garima, Yadav, Anckaerts, Cynthia, Langbeen, An, Leysen, Valerie, Shah, Disha, Jacobs, Jules, Hamaide, Julie, Bols, Peter, Van Audekerke, Johan, Daans, Jasmijn, Guglielmetti, Caroline, Kantarci, Kejal, Prevot, Vincent, Roßner, Steffen, Ponsaerts, Peter, Van der Linden, Annemie, Verhoye, Marleen
Published in Neurobiology of aging (01.06.2021)
Published in Neurobiology of aging (01.06.2021)
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Journal Article
Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer’s disease
Bhattarai, Prabesh, Gunasekaran, Tamil Iniyan, Belloy, Michael E., Reyes-Dumeyer, Dolly, Jülich, Dörthe, Tayran, Hüseyin, Yilmaz, Elanur, Flaherty, Delaney, Turgutalp, Bengisu, Sukumar, Gauthaman, Alba, Camille, McGrath, Elisa Martinez, Hupalo, Daniel N., Bacikova, Dagmar, Le Guen, Yann, Lantigua, Rafael, Medrano, Martin, Rivera, Diones, Recio, Patricia, Nuriel, Tal, Ertekin-Taner, Nilüfer, Teich, Andrew F., Dickson, Dennis W., Holley, Scott, Greicius, Michael, Dalgard, Clifton L., Zody, Michael, Mayeux, Richard, Kizil, Caghan, Vardarajan, Badri N.
Published in Acta neuropathologica (01.06.2024)
Published in Acta neuropathologica (01.06.2024)
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Journal Article
A novel age-informed approach for genetic association analysis in Alzheimer's disease
Le Guen, Yann, Belloy, Michael E, Napolioni, Valerio, Eger, Sarah J, Kennedy, Gabriel, Tao, Ran, He, Zihuai, Greicius, Michael D
Published in Alzheimer's research & therapy (01.04.2021)
Published in Alzheimer's research & therapy (01.04.2021)
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Journal Article
A novel age‐informed approach for genetic association analysis in Alzheimer’s disease
Guen, Yann Le, Belloy, Michael E, Napolioni, Valerio, Eger, Sarah J, Kennedy, Gabriel, Tao, Ran, He, Zihuai, Greicius, Michael D
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
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Journal Article
A Quarter Century of APOE and Alzheimer’s Disease: Progress to Date and the Path Forward
Belloy, Michaël E., Napolioni, Valerio, Greicius, Michael D.
Published in Neuron (Cambridge, Mass.) (06.03.2019)
Published in Neuron (Cambridge, Mass.) (06.03.2019)
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