Mechanisms of DNA–protein crosslink repair
Stingele, Julian, Bellelli, Roberto, Boulton, Simon J.
Published in Nature reviews. Molecular cell biology (01.09.2017)
Published in Nature reviews. Molecular cell biology (01.09.2017)
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Journal Article
Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe
Margalef, Pol, Kotsantis, Panagiotis, Borel, Valerie, Bellelli, Roberto, Panier, Stephanie, Boulton, Simon J.
Published in Cell (25.01.2018)
Published in Cell (25.01.2018)
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Journal Article
Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN
Stingele, Julian, Bellelli, Roberto, Alte, Ferdinand, Hewitt, Graeme, Sarek, Grzegorz, Maslen, Sarah L., Tsutakawa, Susan E., Borg, Annabel, Kjær, Svend, Tainer, John A., Skehel, J. Mark, Groll, Michael, Boulton, Simon J.
Published in Molecular cell (17.11.2016)
Published in Molecular cell (17.11.2016)
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Journal Article
NCOA4 Deficiency Impairs Systemic Iron Homeostasis
Bellelli, Roberto, Federico, Giorgia, Matte’, Alessandro, Colecchia, David, Iolascon, Achille, Chiariello, Mario, Santoro, Massimo, De Franceschi, Lucia, Carlomagno, Francesca
Published in Cell reports (Cambridge) (26.01.2016)
Published in Cell reports (Cambridge) (26.01.2016)
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Journal Article
Loss of POLE3-POLE4 unleashes replicative gap accumulation upon treatment with PARP inhibitors
Hill, Bethany Rebekah, Ozgencil, Meryem, Buckley-Benbow, Lauryn, Skingsley, Sophie Louise Pamela, Tomlinson, Danielle, Eizmendi, Carmen Ortueta, Agnarelli, Alessandro, Bellelli, Roberto
Published in Cell reports (Cambridge) (28.05.2024)
Published in Cell reports (Cambridge) (28.05.2024)
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Journal Article
NCOA4 Transcriptional Coactivator Inhibits Activation of DNA Replication Origins
Bellelli, Roberto, Castellone, Maria Domenica, Guida, Teresa, Limongello, Roberto, Dathan, Nina Alayne, Merolla, Francesco, Cirafici, Anna Maria, Affuso, Andrea, Masai, Hisao, Costanzo, Vincenzo, Grieco, Domenico, Fusco, Alfredo, Santoro, Massimo, Carlomagno, Francesca
Published in Molecular cell (03.07.2014)
Published in Molecular cell (03.07.2014)
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Journal Article
FOXM1 is a molecular determinant of the mitogenic and invasive phenotype of anaplastic thyroid carcinoma
Bellelli, Roberto, Castellone, Maria Domenica, Garcia-Rostan, Ginesa, Ugolini, Clara, Nucera, Carmelo, Sadow, Peter M, Nappi, Tito Claudio, Salerno, Paolo, Cantisani, Maria Carmela, Basolo, Fulvio, Gago, Tomas Alvarez, Salvatore, Giuliana, Santoro, Massimo
Published in Endocrine-related cancer (01.10.2012)
Published in Endocrine-related cancer (01.10.2012)
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Journal Article
NCOA4 links iron bioavailability to DNA metabolism
Federico, Giorgia, Carrillo, Federica, Dapporto, Francesca, Chiariello, Mario, Santoro, Massimo, Bellelli, Roberto, Carlomagno, Francesca
Published in Cell reports (Cambridge) (16.08.2022)
Published in Cell reports (Cambridge) (16.08.2022)
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Journal Article
POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication
Bellelli, Roberto, Belan, Ondrej, Pye, Valerie E., Clement, Camille, Maslen, Sarah L., Skehel, J. Mark, Cherepanov, Peter, Almouzni, Genevieve, Boulton, Simon J.
Published in Molecular cell (04.10.2018)
Published in Molecular cell (04.10.2018)
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Journal Article
POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells
Belan, Ondrej, Sebald, Marie, Adamowicz, Marek, Anand, Roopesh, Vancevska, Aleksandra, Neves, Joana, Grinkevich, Vera, Hewitt, Graeme, Segura-Bayona, Sandra, Bellelli, Roberto, Robinson, Helen M.R., Higgins, Geoff S., Smith, Graeme C.M., West, Stephen C., Rueda, David S., Boulton, Simon J.
Published in Molecular cell (15.12.2022)
Published in Molecular cell (15.12.2022)
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Journal Article
Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
Hewitt, Graeme, Borel, Valerie, Segura-Bayona, Sandra, Takaki, Tohru, Ruis, Phil, Bellelli, Roberto, Lehmann, Laura C., Sommerova, Lucia, Vancevska, Aleksandra, Tomas-Loba, Antonia, Zhu, Kang, Cooper, Christopher, Fugger, Kasper, Patel, Harshil, Goldstone, Robert, Schneider-Luftman, Deborah, Herbert, Ellie, Stamp, Gordon, Brough, Rachel, Pettitt, Stephen, Lord, Christopher J., West, Stephen C., Ahel, Ivan, Ahel, Dragana, Chapman, J. Ross, Deindl, Sebastian, Boulton, Simon J.
Published in Molecular cell (18.02.2021)
Published in Molecular cell (18.02.2021)
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Journal Article
Multiple roles of Pol epsilon in eukaryotic chromosome replication
Cvetkovic, Milos A, Ortega, Esther, Bellelli, Roberto, Costa, Alessandro
Published in Biochemical Society transactions (28.02.2022)
Published in Biochemical Society transactions (28.02.2022)
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Journal Article
RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions
Kotsantis, Panagiotis, Segura-Bayona, Sandra, Margalef, Pol, Marzec, Paulina, Ruis, Phil, Hewitt, Graeme, Bellelli, Roberto, Patel, Harshil, Goldstone, Robert, Poetsch, Anna R., Boulton, Simon J.
Published in Cell reports (Cambridge) (22.12.2020)
Published in Cell reports (Cambridge) (22.12.2020)
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Journal Article
Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis
Bellelli, Roberto, Borel, Valerie, Logan, Clare, Svendsen, Jennifer, Cox, Danielle E., Nye, Emma, Metcalfe, Kay, O’Connell, Susan M., Stamp, Gordon, Flynn, Helen R., Snijders, Ambrosius P., Lassailly, François, Jackson, Andrew, Boulton, Simon J.
Published in Molecular cell (17.05.2018)
Published in Molecular cell (17.05.2018)
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Journal Article
DNA Polymerase Epsilon Deficiency Causes IMAGe Syndrome with Variable Immunodeficiency
Logan, Clare V., Murray, Jennie E., Parry, David A., Robertson, Andrea, Bellelli, Roberto, Tarnauskaitė, Žygimantė, Challis, Rachel, Cleal, Louise, Borel, Valerie, Fluteau, Adeline, Santoyo-Lopez, Javier, Aitman, Timothy J., Biankin, Andrew V., Cooke, Susanna L., Humphrey, Wendy Inglis, Martin, Sancha, Mennie, Lynne, Meynert, Alison, Miedzybrodzka, Zosia, Murphy, Fiona, Nourse, Craig, Santoyo-Lopez, Javier, Semple, Colin A., Williams, Nicola, Aitman, Tim, Barroso, Inês, Basel, Donald, Bicknell, Louise S., Goel, Himanshu, Hu, Hao, Huff, Chad, Hutchison, Michele, Joyce, Caroline, Knox, Rachel, Lacroix, Amy E., Langlois, Sylvie, McCandless, Shawn, McCarrier, Julie, Metcalfe, Kay A., Morrissey, Rose, Murphy, Nuala, Netchine, Irène, O’Connell, Susan M., Olney, Ann Haskins, Paria, Nandina, Rosenfeld, Jill A., Sherlock, Mark, Syverson, Erin, White, Perrin C., Wise, Carol, Yu, Yao, Zacharin, Margaret, Banerjee, Indraneel, Reijns, Martin, Bober, Michael B., Semple, Robert K., Boulton, Simon J., Rios, Jonathan J., Jackson, Andrew P.
Published in American journal of human genetics (06.12.2018)
Published in American journal of human genetics (06.12.2018)
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Journal Article
NCOA4 Links Iron Bioavailability to DNA Metabolism
Federico, Giorgia, Bellelli, Roberto, Nai, Antonella, Silvestri, Laura, Camaschella, Clara, Iolascon, Achille, Santoro, Massimo, Carlomagno, Francesca
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Disrupted control of origin activation compromises genome integrity upon destabilization of Polε and dysfunction of the TRP53-CDKN1A/P21 axis
Borel, Valerie, Boeing, Stefan, Van Wietmarschen, Niek, Sridharan, Sriram, Hill, Bethany Rebekah, Ombrato, Luigi, Perez-Lloret, Jimena, Jackson, Deb, Goldstone, Robert, Boulton, Simon J., Nussenzweig, Andre, Bellelli, Roberto
Published in Cell reports (Cambridge) (31.05.2022)
Published in Cell reports (Cambridge) (31.05.2022)
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Journal Article