Signal peptide-binding drug as a selective inhibitor of co-translational protein translocation
Vermeire, Kurt, Bell, Thomas W, Van Puyenbroeck, Victor, Giraut, Anne, Noppen, Sam, Liekens, Sandra, Schols, Dominique, Hartmann, Enno, Kalies, Kai-Uwe, Marsh, Mark
Published in PLoS biology (01.12.2014)
Published in PLoS biology (01.12.2014)
Get full text
Journal Article
Synthesis and Photoisomerization of Substituted Dibenzofulvene Molecular Rotors
Everhart, Stephanie C., Jayasundara, Udaya K., Kim, HyunJong, Procúpez-Schtirbu, Rolando, Stanbery, Wayne A., Mishler, Clay H., Frost, Brian J., Cline, Joseph I., Bell, Thomas W.
Published in Chemistry : a European journal (01.08.2016)
Published in Chemistry : a European journal (01.08.2016)
Get full text
Journal Article
The signal peptide as a new target for drug design
Lumangtad, Liezel A., Bell, Thomas W.
Published in Bioorganic & medicinal chemistry letters (15.05.2020)
Published in Bioorganic & medicinal chemistry letters (15.05.2020)
Get full text
Journal Article
Comparison of in vitro membrane permeabilities of diverse environmental chemicals with in silico predictions
Intasiri, Amarawan, Illa, Siena E., Prertprawnon, Supadach, Wang, Shenghong, Li, Li, Bell, Thomas W., Li, Dingsheng
Published in The Science of the total environment (10.07.2024)
Published in The Science of the total environment (10.07.2024)
Get full text
Journal Article
Tsuji–Trost Cyclization of Disulfonamides: Synthesis of 12-Membered, 11-Membered, and Pyridine-Fused Macrocyclic Triamines
Ali, Rameez, Anugu, Sreenivasa, Chawla, Reena, Demillo, Violeta G, Goulinet-Mateo, Florian, Gyawali, Sagar, Hamal, Sunil, Jones, Dylan E, Lamprecht, Katrin, Le, Truc, Lumangtad, Liezel A, Pflug, Nicholas C, Sama, Alekhya, Scarbrough, Emily D, Bell, Thomas W
Published in ACS omega (31.01.2019)
Published in ACS omega (31.01.2019)
Get full text
Journal Article
Controlling the Spatial Orientation of Molecular Actuators: Polarized Photoisomerization of 2-Nitro-9-(2,2,2-triphenylethylidene)fluorene in a Thin Polymer Matrix
Ismail, Ali I, Mantha, Jordan H, Kim, Hyun Jong, Bell, Thomas W, Cline, Joseph I
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (03.02.2011)
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (03.02.2011)
Get full text
Journal Article
Role of Sec61α2 translocon in insulin biosynthesis
Xu, Xiaoxi, Bell, Thomas W, Le, Truc, Zhao, Ivy, Walker, Emily, Wang, Yiqing, Xu, Ning, Soleimanpour, Scott A, Russ, Holger A, Qi, Ling, Tsai, Billy, Liu, Ming, Arvan, Peter
Published in Diabetes (New York, N.Y.) (26.09.2024)
Published in Diabetes (New York, N.Y.) (26.09.2024)
Get full text
Journal Article
Human Immunodeficiency Virus Type 1 Escape from Cyclotriazadisulfonamide-Induced CD4-Targeted Entry Inhibition Is Associated with Increased Neutralizing Antibody Susceptibility
VERMEIRE, Kurt, VAN LAETHEM, Kristel, JANSSENS, Wouter, BELL, Thomas W, SCHOLS, Dominique
Published in Journal of Virology (01.09.2009)
Published in Journal of Virology (01.09.2009)
Get full text
Journal Article
Syntheses and anti-HIV and human cluster of differentiation 4 (CD4) down-modulating potencies of pyridine-fused cyclotriazadisulfonamide (CADA) compounds
Lumangtad, Liezel A., Claeys, Elisa, Hamal, Sunil, Intasiri, Amarawan, Basrai, Courtney, Yen-Pon, Expedite, Beenfeldt, Davison, Vermeire, Kurt, Bell, Thomas W.
Published in Bioorganic & medicinal chemistry (15.12.2020)
Published in Bioorganic & medicinal chemistry (15.12.2020)
Get full text
Journal Article
Full Visible Spectrum and White Light Emission with a Single, Input-Tunable Organic Fluorophore
Zavaleta, Andrés, Lykhin, Aleksandr O, Monteiro, Jorge H. S. K, Uchida, Shoto, Bell, Thomas W, de Bettencourt-Dias, Ana, Varganov, Sergey A, Gallucci, Judith
Published in Journal of the American Chemical Society (02.12.2020)
Published in Journal of the American Chemical Society (02.12.2020)
Get full text
Journal Article
Isoform selectivities of novel 4-hydroxycoumarin imines as inhibitors of myosin II
Smith, Joshua D., Brawley, Jhonnathan, Bordenave, Kate C., Olsen, Ryan K., Intasiri, Amarawan, Cremo, Christine R., Bell, Thomas W.
Published in European journal of medicinal chemistry (05.02.2023)
Published in European journal of medicinal chemistry (05.02.2023)
Get full text
Journal Article
Synthesis and Evaluation of 4‑Hydroxycoumarin Imines as Inhibitors of Class II Myosins
Brawley, Jhonnathan, Etter, Emily, Heredia, Dante, Intasiri, Amarawan, Nennecker, Kyle, Smith, Joshua, Welcome, Brandon M, Brizendine, Richard K, Gould, Thomas W, Bell, Thomas W, Cremo, Christine
Published in Journal of medicinal chemistry (08.10.2020)
Published in Journal of medicinal chemistry (08.10.2020)
Get full text
Journal Article
A Proteomic Survey Indicates Sortilin as a Secondary Substrate of the ER Translocation Inhibitor Cyclotriazadisulfonamide (CADA)
Van Puyenbroeck, Victor, Claeys, Elisa, Schols, Dominique, Bell, Thomas W., Vermeire, Kurt
Published in Molecular & cellular proteomics (01.02.2017)
Published in Molecular & cellular proteomics (01.02.2017)
Get full text
Journal Article
Preprotein signature for full susceptibility to the co‐translational translocation inhibitor cyclotriazadisulfonamide
Van Puyenbroeck, Victor, Pauwels, Eva, Provinciael, Becky, Bell, Thomas W., Schols, Dominique, Kalies, Kai‐Uwe, Hartmann, Enno, Vermeire, Kurt
Published in Traffic (Copenhagen, Denmark) (01.02.2020)
Published in Traffic (Copenhagen, Denmark) (01.02.2020)
Get full text
Journal Article
Reduction of Progranulin-Induced Breast Cancer Stem Cell Propagation by Sortilin-Targeting Cyclotriazadisulfonamide (CADA) Compounds
Berger, Karoline, Pauwels, Eva, Parkinson, Gabrielle, Landberg, Göran, Le, Truc, Demillo, Violeta G, Lumangtad, Liezel A, Jones, Dylan E, Islam, Md Azizul, Olsen, Ryan, Kapri, Topprasad, Intasiri, Amarawan, Vermeire, Kurt, Rhost, Sara, Bell, Thomas W
Published in Journal of medicinal chemistry (09.09.2021)
Published in Journal of medicinal chemistry (09.09.2021)
Get full text
Journal Article
Tuning Side Arm Electronics in Unsymmetrical Cyclotriazadisulfonamide (CADA) Endoplasmic Reticulum (ER) Translocation Inhibitors to Improve their Human Cluster of Differentiation 4 (CD4) Receptor Down-Modulating Potencies
Chawla, Reena, Van Puyenbroeck, Victor, Pflug, Nicholas C, Sama, Alekhya, Ali, Rameez, Schols, Dominique, Vermeire, Kurt, Bell, Thomas W
Published in Journal of medicinal chemistry (24.03.2016)
Published in Journal of medicinal chemistry (24.03.2016)
Get full text
Journal Article
The Anti-HIV Potency of Cyclotriazadisulfonamide Analogs Is Directly Correlated with Their Ability to Down-Modulate the CD4 Receptor
Vermeire, Kurt, Bell, Thomas W, Choi, Heung-Jin, Jin, Qi, Samala, Meinrado F, Sodoma, Andrej, De Clercq, Erik, Schols, Dominique
Published in Molecular pharmacology (01.01.2003)
Published in Molecular pharmacology (01.01.2003)
Get full text
Journal Article