Intestinal TGR5 agonism improves hepatic steatosis and insulin sensitivity in Western diet-fed mice
Finn, Patricia D, Rodriguez, David, Kohler, Jill, Jiang, Zhengfeng, Wan, Sindy, Blanco, Erick, King, Andrew J, Chen, Tao, Bell, Noah, Dragoli, Dean, Jacobs, Jeffrey W, Jain, Rakesh, Leadbetter, Michael, Siegel, Matthew, Carreras, Christopher W, Koo-McCoy, Samantha, Shaw, Karen, Le, Cathy, Vanegas, Sandra, Hsu, I-Hsin, Kozuka, Kenji, Okamoto, Keiko, Caldwell, Jeremy S, Lewis, Jason G
Published in American journal of physiology: Gastrointestinal and liver physiology (01.03.2019)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.03.2019)
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Intestinal inhibition of the Na+/H+ exchanger 3 prevents cardiorenal damage in rats and inhibits Na+ uptake in humans
Spencer, Andrew G, Labonte, Eric D, Rosenbaum, David P, Plato, Craig F, Carreras, Christopher W, Leadbetter, Michael R, Kozuka, Kenji, Kohler, Jill, Koo-McCoy, Samantha, He, Limin, Bell, Noah, Tabora, Jocelyn, Joly, Kristin M, Navre, Marc, Jacobs, Jeffrey W, Charmot, Dominique
Published in Science translational medicine (12.03.2014)
Published in Science translational medicine (12.03.2014)
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Gastrointestinal Inhibition of Sodium-Hydrogen Exchanger 3 Reduces Phosphorus Absorption and Protects against Vascular Calcification in CKD
Labonté, Eric D., Carreras, Christopher W., Leadbetter, Michael R., Kozuka, Kenji, Kohler, Jill, Koo-McCoy, Samantha, He, Limin, Dy, Edward, Black, Deborah, Zhong, Ziyang, Langsetmo, Ingrid, Spencer, Andrew G., Bell, Noah, Deshpande, Desiree, Navre, Marc, Lewis, Jason G., Jacobs, Jeffrey W., Charmot, Dominique
Published in Journal of the American Society of Nephrology (01.05.2015)
Published in Journal of the American Society of Nephrology (01.05.2015)
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Journal Article
MODL-48. AUTOMATING ANALYSIS OF ORGANOTYPIC BRAIN SLICE CULTURE USING MACHINE LEARNING-POWERED COMPUTER VISION
Bell, Noah, Buckley, Andrew, Mann, Breanna, Adefolaju, Adebimpe, Dasari, Rajaneekar, Hingtgen, Shawn, Satterlee, Andrew B
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
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Journal Article
MODL-13. ORGANOTYPIC BRAIN SLICE CULTURE PLATFORM AS A MODEL OF PEDIATRIC LOW GRADE GLIOMAS
Mann, Breanna, Artz, Nichole, Adefolaju, Adebimpe, Dasari, Rajaneekar, Bell, Noah, Buckley, Andrew, Kram, David, Hingtgen, Shawn, Satterlee, Andrew
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
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Journal Article
MODL-41. ORGANOTYPIC BRAIN SLICE CULTURE PLATFORM AS A NOVEL PRE-CLINICAL MODEL FOR PATIENT DERIVED CELL LINES
Mann, Breanna, Zhang, Xiaopei, Bell, Noah, Adefolaju, Adebimpe, Dasari, Rajaneekar, Hingtgen, Shawn, Satterlee, Andrew
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
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MODL-27. An organotypic brain slice culture platform as a novel pre-clinical model for diffuse intrinsic pontine glioma and diffuse midline glioma
Mann, Breanna, Zhang, Xiaopei, Bell, Noah, Adefolaju, Adebimpe, Dasari, Rajaneekar, Valdivia, Alain, Buckley, Andrew, Quinsey, Carolyn, Hingtgen, Shawn, Satterlee, Andrew
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
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Journal Article
Gastrointestinal Inhibition of Sodium-Hydrogen Exchanger 3 Reduces Phosphorus Absorption and Protects against Vascular Calcification in CKD
Labonté, Eric D, Carreras, Christopher W, Leadbetter, Michael R, Kozuka, Kenji, Kohler, Jill, Koo-McCoy, Samantha, He, Limin, Dy, Edward, Black, Deborah, Zhong, Ziyang, Langsetmo, Ingrid, Spencer, Andrew G, Bell, Noah, Deshpande, Desiree, Navre, Marc, Lewis, Jason G, Jacobs, Jeffrey W, Charmot, Dominique
Published in Journal of the American Society of Nephrology (01.05.2015)
Published in Journal of the American Society of Nephrology (01.05.2015)
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EXTH-01. SECOND GENERATION OF INDUCED NEURAL STEM CELLS TO MIGRATE AND KILL AS AN ADJUVANT TO RADIOTHERAPY IN NON-SMALL CELL LUNG CANCER METASTASIS
Mercer-Smith, Alison, Thang, Morrent, Buckley, Andrew, Valdivia, Alain, Jiang, Wulin, Bell, Noah, Kumar, Rashmi, Bomba, Hunter, Woodell, Alex, Luo, Daniel, Floyd, Scott, Hingtgen, Shawn
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
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Journal Article
Design of Gut-Restricted Thiazolidine Agonists of G Protein-Coupled Bile Acid Receptor 1 (GPBAR1, TGR5)
Chen, Tao, Reich, Nicholas William, Bell, Noah, Finn, Patricia D, Rodriguez, David, Kohler, Jill, Kozuka, Kenji, He, Limin, Spencer, Andrew G, Charmot, Dominique, Navre, Marc, Carreras, Christopher W, Koo-McCoy, Samantha, Tabora, Jocelyn, Caldwell, Jeremy S, Jacobs, Jeffrey W, Lewis, Jason Gustaf
Published in Journal of medicinal chemistry (13.09.2018)
Published in Journal of medicinal chemistry (13.09.2018)
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CNSC-39. GENERATION AND CHARACTERIZATION OF LIVING ORGANOTYPIC BRAIN SLICE CULTURES AS A NOVEL PRE-CLINICAL MODEL FOR BRAIN CANCER
Dasari, Rajaneekar, Mann, Breanna, Zhang, Xiaopei, Bell, Noah, Adefolaju, Adebimpe, Thang, Morrent, Kanchi, Krishna, Valdivia, Alain, Yang, Yang, Buckley, Andrew, Lettry, Vivien, Quinsey, Carolyn, Rauf, Yasmeen, Kram, David, Cassidy, Noah, Vaziri, Cyrus, Corcoran, David L, Rego, Stephen, Jiang, Yuchao, Graves, Lee M, Dunn, Denise, Floyd, Scott, Baldwin, Albert, Hingtgen, Shawn, Satterlee, Andrew B
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
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Journal Article
MODL-44. DEVELOPMENT OF A NOVEL, PERSONALIZED DRUG SENSITIVITY SCORE TO ASSESS TUMOR KILLING AND TOXICITY WITHIN AN ORGANOTYPIC BRAIN SLICE CULTURE PLATFORM
Mann, Breanna, Zhang, Xiaopei, Bell, Noah, Adefolaju, Adebimpe, Thang, Morrent, Dasari, Rajaneekar, Kanchi, Krishna, Valdivia, Alain, Yang, Yang, Buckley, Andrew, Lettry, Vivien, Quinsey, Carolyn, Rauf, Yasmeen, Kram, David, Cassidy, Noah, Vaziri, Cyrus, Corcoran, David L, Rego, Stephen, Jiang, Yuchao, Graves, Lee M, Dunn, Denise, Floyd, Scott, Baldwin, Albert, Hingtgen, Shawn, Satterlee, Andrew B
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
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MODL-03. AN EX VIVO PLATFORM BASED ON ORGANOTYPIC BRAIN SLICE CULTURE FOR INFORMING PERSONALIZED BRAIN CANCER THERAPY
Zhang, Xiaopei, Mann, Breanna, Bell, Noah, Adefolaju, Adebimpe, Thang, Morrent, Dasari, Rajaneekar, Kanchi, Krishna, Valdivia, Alain, Yang, Yang, Buckley, Andrew, Lettry, Vivien, Quinsey, Carolyn, Rauf, Yasmeen, Kram, David, Cassidy, Noah, Vaziri, Cyrus, Corcoran, David L, Rego, Stephen, Jiang, Yuchao, Graves, Lee M, Dunn, Denise, Floyd, Scott, Baldwin, Albert, Hingtgen, Shawn, Satterlee, Andrew B
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
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Journal Article
MODL-28. LIVING EX VIVO ORGANOTYPIC BRAIN SLICE CULTURES AS A COMPREHENSIVE SUBSTRATE FOR TUMOR ENGRAFTMENT AND ANALYSIS
Adefolaju, Adebimpe, Mann, Breanna, Zhang, Xiaopei, Bell, Noah, Thang, Morrent, Dasari, Rajaneekar, Kanchi, Krishna, Valdivia, Alain, Yang, Yang, Buckley, Andrew, Lettry, Vivien, Quinsey, Carolyn, Rauf, Yasmeen, Kram, David, Cassidy, Noah, Vaziri, Cyrus, Corcoran, David L, Rego, Stephen, Jiang, Yuchao, Graves, Lee M, Dunn, Denise, Floyd, Scott, Baldwin, Albert, Hingtgen, Shawn, Satterlee, Andrew B
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
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MMAP-04 CYTOTOXIC, TUMOR-HOMING INDUCED NEURAL STEM CELLS AS AN ADJUVANT TO RADIATION IN THE TREATMENT OF NON-SMALL CELL LUNG CANCER LEPTOMENINGEAL METASTASES
Mercer-Smith, Alison, Jiang, Wulin, Valdivia, Alain, Bell, Noah, Woodell, Alex, Floyd, Scott, Hingtgen, Shawn
Published in Neuro-oncology advances (05.08.2022)
Published in Neuro-oncology advances (05.08.2022)
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Journal Article
Optimization of novel reversible Bruton’s tyrosine kinase inhibitors identified using Tethering-fragment-based screens
Hopkins, Brian T., Bame, Eris, Bell, Noah, Bohnert, Tonika, Bowden-Verhoek, Jon K., Bui, Minna, Cancilla, Mark T., Conlon, Patrick, Cullen, Patrick, Erlanson, Daniel A., Fan, Junfa, Fuchs-Knotts, Tarra, Hansen, Stig, Heumann, Stacey, Jenkins, Tracy J., Marcotte, Douglas, McDowell, Bob, Mertsching, Elisabeth, Negrou, Ella, Otipoby, Kevin L., Poreci, Urjana, Romanowski, Michael J., Scott, Daniel, Silvian, Laura, Yang, Wenjin, Zhong, Min
Published in Bioorganic & medicinal chemistry (01.07.2019)
Published in Bioorganic & medicinal chemistry (01.07.2019)
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Utilizing structure based drug design and metabolic soft spot identification to optimize the in vitro potency and in vivo pharmacokinetic properties leading to the discovery of novel reversible Bruton’s tyrosine kinase inhibitors
Hopkins, Brian T., Bame, Eris, Bell, Noah, Bohnert, Tonika, Bowden-Verhoek, Jon K., Bui, Minna, Cancilla, Mark T., Conlon, Patrick, Cullen, Patrick, Erlanson, Daniel A., Fan, Junfa, Fuchs-Knotts, Tarra, Hansen, Stig, Heumann, Stacey, Jenkins, Tracy J., Gua, Chuck, Liu, Ying, Liu, YuTing, Lulla, Mukush, Marcotte, Douglas, Marx, Isaac, McDowell, Bob, Mertsching, Elisabeth, Negrou, Ella, Romanowski, Michael J., Scott, Daniel, Silvian, Laura, Yang, Wenjin, Zhong, Min
Published in Bioorganic & medicinal chemistry (15.08.2021)
Published in Bioorganic & medicinal chemistry (15.08.2021)
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Discovery of Tenapanor: A First-in-Class Minimally Systemic Inhibitor of Intestinal Na+/H+ Exchanger Isoform 3
Jacobs, Jeffrey W., Leadbetter, Michael R., Bell, Noah, Koo-McCoy, Samantha, Carreras, Christopher W., He, Limin, Kohler, Jill, Kozuka, Kenji, Labonté, Eric D., Navre, Marc, Spencer, Andrew G., Charmot, Dominique
Published in ACS medicinal chemistry letters (14.07.2022)
Published in ACS medicinal chemistry letters (14.07.2022)
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COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS
CARRERAS CHRIS, JACOBS JEFFREY W, LEADBETTER MICHAEL ROBERT, BELL NOAH, CHARMOT DOMINIQUE, NAVRE MARC
Year of Publication 05.04.2022
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Year of Publication 05.04.2022
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