Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimer’s disease and other tauopathies
Xia, Yuxing, Prokop, Stefan, Gorion, Kimberly-Marie M, Kim, Justin D, Sorrentino, Zachary A, Bell, Brach M, Manaois, Alyssa N, Chakrabarty, Paramita, Davies, Peter, Giasson, Benoit I
Published in Acta neuropathologica communications (22.06.2020)
Published in Acta neuropathologica communications (22.06.2020)
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Novel Conformation-Dependent Tau Antibodies Are Modulated by Adjacent Phosphorylation Sites
Paterno, Giavanna, Torrellas, Jose, Bell, Brach M, Gorion, Kimberly-Marie M, Quintin, Stephan S, Hery, Gabriela P, Prokop, Stefan, Giasson, Benoit I
Published in International journal of molecular sciences (01.09.2023)
Published in International journal of molecular sciences (01.09.2023)
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A multiverse of α-synuclein: investigation of prion strain properties with carboxyl-terminal truncation specific antibodies in animal models
Lloyd, Grace M, Quintin, Stephan, Sorrentino, Zachary A, Gorion, Kimberly-Marie M, Bell, Brach M, Long, Brooke, Paterno, Giavanna, Giasson, Benoit I
Published in Acta neuropathologica communications (10.06.2024)
Published in Acta neuropathologica communications (10.06.2024)
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Carboxyl truncation of α-synuclein occurs early and is influenced by human APOE genotype in transgenic mouse models of α-synuclein pathogenesis
Lloyd, Grace M, Long, Brooke, Quintin, Stephan, Sorrentino, Zachary A, Gorion, Kimberly-Marie M, Bell, Brach M, Carrillo, Denise, Sullivan, Patrick, Borchelt, David, Giasson, Benoit I
Published in Acta neuropathologica communications (23.07.2023)
Published in Acta neuropathologica communications (23.07.2023)
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Novel Monoclonal Antibody Specific toward Amyloid-β Binds to a Unique Epitope within the N-Terminal Region
Paterno, Giavanna, Moore, Brenda D, Bell, Brach M, Gorion, Kimberly-Marie M, Ran, Yong, Prokop, Stefan, Golde, Todd E, Giasson, Benoit I
Published in Antibodies (Basel) (09.08.2024)
Published in Antibodies (Basel) (09.08.2024)
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Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice
Xia, Yuxing, Prokop, Stefan, Bell, Brach M., Gorion, Kimberly-Marie M., Croft, Cara L., Nasif, Lith, Xu, Guilian, Riffe, Cara J., Manaois, Alyssa N., Strang, Kevin H., Quintin, Stephan S., Paterno, Giavanna, Tansey, Malú Gámez, Borchelt, David R., Golde, Todd E., Giasson, Benoit I.
Published in Communications biology (12.05.2022)
Published in Communications biology (12.05.2022)
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Cellular processing of α-synuclein fibrils results in distinct physiological C-terminal truncations with a major cleavage site at residue Glu 114
Quintin, Stephan, Lloyd, Grace M., Paterno, Giavanna, Xia, Yuxing, Sorrentino, Zachary, Bell, Brach M., Gorion, Kimberly-Marie, Lee, Edward B., Prokop, Stefan, Giasson, Benoit I.
Published in The Journal of biological chemistry (01.07.2023)
Published in The Journal of biological chemistry (01.07.2023)
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Unique seeding profiles and prion-like propagation of synucleinopathies are highly dependent on the host in human α-synuclein transgenic mice
Lloyd, Grace M., Sorrentino, Zachary A., Quintin, Stephan, Gorion, Kimberly-Marie M., Bell, Brach M., Paterno, Giavanna, Long, Brooke, Prokop, Stefan, Giasson, Benoit I.
Published in Acta neuropathologica (01.06.2022)
Published in Acta neuropathologica (01.06.2022)
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Unique seeding profiles and prion-like propagation of synucleinopathies are highly dependent on the host in human [alpha]-synuclein transgenic mice
Lloyd, Grace M, Sorrentino, Zachary A, Quintin, Stephan, Gorion, Kimberly-Marie M, Bell, Brach M, Paterno, Giavanna, Long, Brooke
Published in Acta neuropathologica (01.06.2022)
Published in Acta neuropathologica (01.06.2022)
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Journal Article
A multiverse of [alpha]-synuclein: investigation of prion strain properties with carboxyl-terminal truncation specific antibodies in animal models
Lloyd, Grace M, Quintin, Stephan, Sorrentino, Zachary A, Gorion, Kimberly-Marie M, Bell, Brach M, Long, Brooke, Paterno, Giavanna, Giasson, Benoit I
Published in Acta neuropathologica communications (10.06.2024)
Published in Acta neuropathologica communications (10.06.2024)
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Journal Article
Carboxyl truncation of [alpha]-synuclein occurs early and is influenced by human APOE genotype in transgenic mouse models of [alpha]-synuclein pathogenesis
Lloyd, Grace M, Long, Brooke, Quintin, Stephan, Sorrentino, Zachary A, Gorion, Kimberly-Marie M, Bell, Brach M, Carrillo, Denise, Sullivan, Patrick, Borchelt, David, Giasson, Benoit I
Published in Acta neuropathologica communications (23.07.2023)
Published in Acta neuropathologica communications (23.07.2023)
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