Genomic landscape of metastatic breast cancer identifies preferentially dysregulated pathways and targets
Paul, Matt R, Pan, Tien-Chi, Pant, Dhruv K, Shih, Natalie Nc, Chen, Yan, Harvey, Kyra L, Solomon, Aaron, Lieberman, David, Morrissette, Jennifer Jd, Soucier-Ernst, Danielle, Goodman, Noah G, Stavropoulos, S William, Maxwell, Kara N, Clark, Candace, Belka, George K, Feldman, Michael, DeMichele, Angela, Chodosh, Lewis A
Published in The Journal of clinical investigation (01.08.2020)
Published in The Journal of clinical investigation (01.08.2020)
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Notch promotes recurrence of dormant tumor cells following HER2/neu-targeted therapy
Abravanel, Daniel L, Belka, George K, Pan, Tien-chi, Pant, Dhruv K, Collins, Meredith A, Sterner, Christopher J, Chodosh, Lewis A
Published in The Journal of clinical investigation (01.06.2015)
Published in The Journal of clinical investigation (01.06.2015)
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Impact of obesity on breast cancer recurrence and minimal residual disease
Ecker, Brett L, Lee, Jun Y, Sterner, Christopher J, Solomon, Aaron C, Pant, Dhruv K, Shen, Fei, Peraza, Javier, Vaught, Lauren, Mahendra, Samyukta, Belka, George K, Pan, Tien-Chi, Schmitz, Kathryn H, Chodosh, Lewis A
Published in Breast cancer research : BCR (13.03.2019)
Published in Breast cancer research : BCR (13.03.2019)
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PAQR8 promotes breast cancer recurrence and confers resistance to multiple therapies
Chen, Saisai, Paul, Matt R, Sterner, Christopher J, Belka, George K, Wang, Dezhen, Xu, Peining, Sreekumar, Amulya, Pan, Tien-Chi, Pant, Dhruv K, Makhlin, Igor, DeMichele, Angela, Mesaros, Clementina, Chodosh, Lewis A
Published in Breast cancer research : BCR (03.01.2023)
Published in Breast cancer research : BCR (03.01.2023)
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Oncogene pathway activation in mammary tumors dictates FDG-PET uptake
Alvarez, James V, Belka, George K, Pan, Tien-Chi, Chen, Chien-Chung, Blankemeyer, Eric, Alavi, Abass, Karp, Joel S, Chodosh, Lewis A
Published in Cancer research (Chicago, Ill.) (15.12.2014)
Published in Cancer research (Chicago, Ill.) (15.12.2014)
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Cellular dormancy in minimal residual disease following targeted therapy
Ruth, Jason R, Pant, Dhruv K, Pan, Tien-Chi, Seidel, Hans E, Baksh, Sanjeethan C, Keister, Blaine A, Singh, Rita, Sterner, Christopher J, Bakewell, Suzanne J, Moody, Susan E, Belka, George K, Chodosh, Lewis A
Published in Breast cancer research : BCR (04.06.2021)
Published in Breast cancer research : BCR (04.06.2021)
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Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways
Chen, Chien-Chung, Stairs, Douglas B, Boxer, Robert B, Belka, George K, Horseman, Nelson D, Alvarez, James V, Chodosh, Lewis A
Published in Genes & development (01.10.2012)
Published in Genes & development (01.10.2012)
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Rare subclonal sequencing of breast cancers indicates putative metastatic driver mutations are predominately acquired after dissemination
Lawrence-Paul, Matthew R, Pan, Tien-Chi, Pant, Dhruv K, Shih, Natalie N C, Chen, Yan, Belka, George K, Feldman, Michael, DeMichele, Angela, Chodosh, Lewis A
Published in Genome medicine (06.02.2024)
Published in Genome medicine (06.02.2024)
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Hunk negatively regulates c-myc to promote Akt-mediated cell survival and mammary tumorigenesis induced by loss of Pten
Yeh, Elizabeth S., Belka, George K., Vernon, Ann E., Chen, Chien-Chung, Jung, Jason J., Chodosh, Lewis A.
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2013)
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Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis
Gunther, Edward J, Moody, Susan E, Belka, George K, Hahn, Kristina T, Innocent, Nathalie, Dugan, Katherine D, Cardiff, Robert D, Chodosh, Lewis A
Published in Genes & development (15.02.2003)
Published in Genes & development (15.02.2003)
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c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations
Chodosh, Lewis A, D'Cruz, Celina M, Gunther, Edward J, Boxer, Robert B, Hartman, Jennifer L, Sintasath, Louis, Moody, Susan E, Cox, James D, Ha, Seung I, Belka, George K, Golant, Alexander, Cardiff, Robert D
Published in Nature medicine (01.02.2001)
Published in Nature medicine (01.02.2001)
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B3GALT6 promotes dormant breast cancer cell survival and recurrence by enabling heparan sulfate-mediated FGF signaling
Sreekumar, Amulya, Lu, Michelle, Choudhury, Biswa, Pan, Tien-chi, Pant, Dhruv K., Lawrence-Paul, Matthew R., Sterner, Christopher J., Belka, George K., Toriumi, Takashi, Benz, Brian A., Escobar-Aguirre, Matias, Marino, Francesco E., Esko, Jeffrey D., Chodosh, Lewis A.
Published in Cancer cell (08.01.2024)
Published in Cancer cell (08.01.2024)
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WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis
Sreekumar, Amulya, Toneff, Michael J., Toh, Eajer, Roarty, Kevin, Creighton, Chad J., Belka, George K., Lee, Dong-Kee, Xu, Jianming, Chodosh, Lewis A., Richards, JoAnne S., Rosen, Jeffrey M.
Published in Developmental cell (20.11.2017)
Published in Developmental cell (20.11.2017)
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Hormone-induced protection against mammary tumorigenesis is conserved in multiple rat strains and identifies a core gene expression signature induced by pregnancy
BLAKELY, Collin M, STODDARD, Alexander J, BELKA, George K, DUGAN, Katherine D, NOTARFRANCESCO, Kathleen L, MOODY, Susan E, D'CRUZ, Celina M, CHODOSH, Lewis A
Published in Cancer research (Chicago, Ill.) (15.06.2006)
Published in Cancer research (Chicago, Ill.) (15.06.2006)
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Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation
Boxer, Robert B., Stairs, Douglas B., Dugan, Katherine D., Notarfrancesco, Kathleen L., Portocarrero, Carla P., Keister, Blaine A., Belka, George K., Cho, Han, Rathmell, Jeffrey C., Thompson, Craig B., Birnbaum, Morris J., Chodosh, Lewis A.
Published in Cell metabolism (01.12.2006)
Published in Cell metabolism (01.12.2006)
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Functional Microarray Analysis of Mammary Organogenesis Reveals a Developmental Role in Adaptive Thermogenesis
Master, Stephen R, Hartman, Jennifer L, D’Cruz, Celina M, Moody, Susan E, Keiper, Elizabeth A, Ha, Seung I, Cox, James D, Belka, George K, Chodosh, Lewis A
Published in Molecular endocrinology (Baltimore, Md.) (01.06.2002)
Published in Molecular endocrinology (Baltimore, Md.) (01.06.2002)
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A novel approach for next‐generation sequencing of circulating tumor cells
Yee, Stephanie S., Lieberman, David B., Blanchard, Tatiana, Rader, JulieAnn, Zhao, Jianhua, Troxel, Andrea B., DeSloover, Daniel, Fox, Alan J., Daber, Robert D., Kakrecha, Bijal, Sukhadia, Shrey, Belka, George K., DeMichele, Angela M., Chodosh, Lewis A., Morrissette, Jennifer J. D., Carpenter, Erica L.
Published in Molecular genetics & genomic medicine (01.07.2016)
Published in Molecular genetics & genomic medicine (01.07.2016)
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Journal Article
Functional microarray analysis of mammary organogenesis reveals a developmental role in adaptive thermogenesis
Master, Stephen R, Hartman, Jennifer L, D'Cruz, Celina M, Moody, Susan E, Keiper, Elizabeth A, Ha, Seung I, Cox, James D, Belka, George K, Chodosh, Lewis A
Published in Molecular endocrinology (Baltimore, Md.) (01.06.2002)
Published in Molecular endocrinology (Baltimore, Md.) (01.06.2002)
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