Differential translation elongation directs protein synthesis in response to acute glucose deprivation in yeast
Guzikowski, Anna R., Harvey, Alex T., Zhang, Jingxiao, Zhu, Shihui, Begovich, Kyle, Cohn, Molly H., Wilhelm, James E., Zid, Brian M.
Published in RNA biology (31.12.2022)
Published in RNA biology (31.12.2022)
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Journal Article
Conserved metabolite regulation of stress granule assembly via AdoMet
Begovich, Kyle, Vu, Anthony Q, Yeo, Gene, Wilhelm, James E
Published in The Journal of cell biology (03.08.2020)
Published in The Journal of cell biology (03.08.2020)
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Journal Article
Cereblon-based Bifunctional Degrader of SOS1, BTX-6654, Targets Multiple KRAS Mutations and Inhibits Tumor Growth
Begovich, Kyle, Schoolmeesters, Angela, Rajapakse, Navin, Martinez-Terroba, Elena, Kumar, Maneesh, Shakya, Arvind, Lai, Chon, Greene, Steven, Whitefield, Brandon, Okano, Akinori, Mali, Venkat, Huang, Shenlin, Chourasia, Aparajita H, Fung, Leah
Published in Molecular cancer therapeutics (02.04.2024)
Published in Molecular cancer therapeutics (02.04.2024)
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Journal Article
Development of bifunctional CRBN-SOS1 degraders for treatment of mutant KRAS cancers
Begovich, Kyle, Schoolmeesters, Angela, Rajapakse, Navin, Kumar, Maneesh, Martinez-Terroba, Elena, Shakya, Arvind, Whitefield, Brandon, Mali, Venkat, Pagadala, Nataraj, Okano, Akinori, Huang, Shenlin, Chourasia, Aparajita Hoskote, Fung, Leah M.
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Abstract 6056: Identification of first-in-class, orally bioavailable SOS1 bifunctional degraders for the treatment of KRAS- and RTK-driven cancers
Begovich, Kyle, Schoolmeesters, Angela, Rajapakse, Navin, Martinez, Elena, Liu, Qiao, Shakya, Arvind, Okano, Akinori, Mali, Venkat, Huang, Shenlin, Chourasia, Aparajita, Fung, Leah
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Abstract B002: Development of bifunctional CRBN-SOS1 degraders for treatment of mutant KRAS cancers
Begovich, Kyle, Schoolmeesters, Angela, Rajapakse, Navin, Kumar, Maneesh, Martinez-Terroba, Elena, Shakya, Arvind, Whitefield, Brandon, Pagadala, Nataraj, Chourasia, Aparajita, Fung, Leah
Published in Molecular cancer research (01.05.2023)
Published in Molecular cancer research (01.05.2023)
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Abstract 1578: Novel Cereblon mediated bifunctional degraders of SOS1 for treatment of pan-KRAS mutant tumors
Begovich, Kyle, Schoolmeesters, Angela, Rajapakse, Navin, Kumar, Maneesh, Shakya, Arvind, Whitefield, Brandon, Martinez-Terroba, Elena, Pagadala, Nataraj, Huang, Shenlin, Chourasia, Aparajita H., Fung, Leah
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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