Role of cereblon in angiogenesis and in mediating the antiangiogenic activity of immunomodulatory drugs
Beedie, Shaunna L, Huang, Phoebe A, Harris, Emily M, Strope, Jonathan D, Mahony, Christopher, Chau, Cindy H, Vargesson, Neil, Figg, William D
Published in The FASEB journal (01.09.2020)
Published in The FASEB journal (01.09.2020)
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Journal Article
Antiangiogenic Activity and in Silico Cereblon Binding Analysis of Novel Thalidomide Analogs
Peach, Megan L, Beedie, Shaunna L, Chau, Cindy H, Collins, Matthew K, Markolovic, Suzana, Luo, Weiming, Tweedie, David, Steinebach, Christian, Greig, Nigel H, Gütschow, Michael, Vargesson, Neil, Nicklaus, Marc C, Figg, William D
Published in Molecules (Basel, Switzerland) (02.12.2020)
Published in Molecules (Basel, Switzerland) (02.12.2020)
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Journal Article
Preclinical Evaluation of Discorhabdins in Antiangiogenic and Antitumor Models
Harris, Emily M, Strope, Jonathan D, Beedie, Shaunna L, Huang, Phoebe A, Goey, Andrew K L, Cook, Kristina M, Schofield, Christopher J, Chau, Cindy H, Cadelis, Melissa M, Copp, Brent R, Gustafson, Kirk R, Figg, William D
Published in Marine drugs (19.07.2018)
Published in Marine drugs (19.07.2018)
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Journal Article
CPS49‐induced neurotoxicity does not cause limb patterning anomalies in developing chicken embryos
Mahony, Chris, McMenemy, Scott, Rafipay, Alexandra J., Beedie, Shaunna‐Leigh, Fraga, Lucas Rosa, Gütschow, Michael, Figg, William D., Erskine, Lynda, Vargesson, Neil
Published in Journal of anatomy (01.04.2018)
Published in Journal of anatomy (01.04.2018)
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Journal Article
Design, synthesis and biological assessment of N-adamantyl, substituted adamantyl and noradamantyl phthalimidines for nitrite, TNF-α and angiogenesis inhibitory activities
Luo, Weiming, Tweedie, David, Beedie, Shaunna L., Vargesson, Neil, Figg, William D., Greig, Nigel H., Scerba, Michael T.
Published in Bioorganic & medicinal chemistry (01.05.2018)
Published in Bioorganic & medicinal chemistry (01.05.2018)
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Journal Article
In vivo screening and discovery of novel candidate thalidomide analogs in the zebrafish embryo and chicken embryo model systems
Beedie, Shaunna L, Rore, Holly M, Barnett, Shelby, Chau, Cindy H, Luo, Weiming, Greig, Nigel H, Figg, William D, Vargesson, Neil
Published in Oncotarget (31.05.2016)
Published in Oncotarget (31.05.2016)
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Journal Article
Differential Expression of OATP1B3 Mediates Unconjugated Testosterone Influx
Sissung, Tristan M, Ley, Ariel M, Strope, Jonathan D, McCrea, Edel M, Beedie, Shaunna, Peer, Cody J, Shukla, Suneet, van Velkinburgh, Jennifer, Reece, Kelie, Troutman, Sarah, Campbell, Tessa, Fernandez, Elena, Huang, Phoebe, Smith, Jordan, Thakkar, Nilay, Venzon, David J, Brenner, Stefan, Lee, Wooin, Merino, Maria, Luo, Ji, Jager, Walter, Price, Douglas K, Chau, Cindy H, Figg, William D
Published in Molecular cancer research (01.08.2017)
Published in Molecular cancer research (01.08.2017)
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Journal Article
Cereblon gene variants and clinical outcome in multiple myeloma patients treated with lenalidomide
Huang, Phoebe A., Beedie, Shaunna L., Chau, Cindy H., Venzon, David J., Gere, Sheryl, Kazandjian, Dickran, Korde, Neha, Mailankody, Sham, Landgren, Ola, Figg, William D.
Published in Scientific reports (16.10.2019)
Published in Scientific reports (16.10.2019)
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Journal Article
Anticancer Properties of a Novel Class of Tetrafluorinated Thalidomide Analogues
Beedie, Shaunna L, Peer, Cody J, Pisle, Steven, Gardner, Erin R, Mahony, Chris, Barnett, Shelby, Ambrozak, Agnieszka, Gütschow, Michael, Chau, Cindy H, Vargesson, Neil, Figg, William D
Published in Molecular cancer therapeutics (01.10.2015)
Published in Molecular cancer therapeutics (01.10.2015)
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Journal Article
Synthesis, Structural Characterization, and Antiangiogenic Activity of Polyfluorinated Benzamides
Steinebach, Christian, Ambrożak, Agnieszka, Dosa, Stefan, Beedie, Shaunna L., Strope, Jonathan D., Schnakenburg, Gregor, Figg, William D., Gütschow, Michael
Published in ChemMedChem (08.10.2018)
Published in ChemMedChem (08.10.2018)
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Journal Article
Phase II trial of docetaxel, bevacizumab, lenalidomide and prednisone in patients with metastatic castration‐resistant prostate cancer
Madan, Ravi A., Karzai, Fatima H., Ning, Yang‐Min, Adesunloye, Bamidele A., Huang, Xuan, Harold, Nancy, Couvillon, Anna, Chun, Guinevere, Cordes, Lisa, Sissung, Tristan, Beedie, Shaunna L., Dawson, Nancy A., Theoret, Marc R., McLeod, David G., Rosner, Inger, Trepel, Jane B., Lee, Min‐Jung, Tomita, Yusuke, Lee, Sunmin, Chen, Clara, Steinberg, Seth M., Arlen, Philip M., Gulley, James L., Figg, William D., Dahut, William L.
Published in BJU international (01.10.2016)
Published in BJU international (01.10.2016)
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Journal Article
Synthesis and Antiangiogenic Properties of Tetrafluorophthalimido and Tetrafluorobenzamido Barbituric Acids
Ambrożak, Agnieszka, Steinebach, Christian, Gardner, Erin R., Beedie, Shaunna L., Schnakenburg, Gregor, Figg, William D., Gütschow, Michael
Published in ChemMedChem (06.12.2016)
Published in ChemMedChem (06.12.2016)
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Journal Article
Alcohol and Aldehyde Dehydrogenases Contribute to Sex-Related Differences in Clearance of Zolpidem in Rats
Peer, Cody J, Strope, Jonathan D, Beedie, Shaunna, Ley, Ariel M, Holly, Alesia, Calis, Karim, Farkas, Ronald, Parepally, Jagan, Men, Angela, Fadiran, Emmanuel O, Scott, Pamela, Jenkins, Marjorie, Theodore, William H, Sissung, Tristan M
Published in Frontiers in pharmacology (15.08.2016)
Published in Frontiers in pharmacology (15.08.2016)
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Journal Article
Hypoxia Induces Transcriptional and Translational Downregulation of the Type I IFN Pathway in Multiple Cancer Cell Types
Miar, Ana, Arnaiz, Esther, Bridges, Esther, Beedie, Shaunna, Cribbs, Adam P, Downes, Damien J, Beagrie, Robert A, Rehwinkel, Jan, Harris, Adrian L
Published in Cancer research (Chicago, Ill.) (01.12.2020)
Published in Cancer research (Chicago, Ill.) (01.12.2020)
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Journal Article
Hypoxia induces transcriptional and translational downregulation of the type I interferon (IFN) pathway in multiple cancer cell types
Miar, Ana, Arnaiz, Esther, Bridges, Esther, Beedie, Shaunna, Cribbs, Adam P., Downes, Damien J., Beagrie, Robert A., Rehwinkel, Jan, Harris, Adrian L.
Published in Cancer research (Chicago, Ill.) (28.10.2020)
Published in Cancer research (Chicago, Ill.) (28.10.2020)
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Journal Article
Target 2035 - update on the quest for a probe for every protein
Müller, Susanne, Ackloo, Suzanne, Al Chawaf, Arij, Al-Lazikani, Bissan, Antolin, Albert, Baell, Jonathan B, Beck, Hartmut, Beedie, Shaunna, Betz, Ulrich A K, Bezerra, Gustavo Arruda, Brennan, Paul E, Brown, David, Brown, Peter J, Bullock, Alex N, Carter, Adrian J, Chaikuad, Apirat, Chaineau, Mathilde, Ciulli, Alessio, Collins, Ian, Dreher, Jan, Drewry, David, Edfeldt, Kristina, Edwards, Aled M, Egner, Ursula, Frye, Stephen V, Fuchs, Stephen M, Hall, Matthew D, Hartung, Ingo V, Hillisch, Alexander, Hitchcock, Stephen H, Homan, Evert, Kannan, Natarajan, Kiefer, James R, Knapp, Stefan, Kostic, Milka, Kubicek, Stefan, Leach, Andrew R, Lindemann, Sven, Marsden, Brian D, Matsui, Hisanori, Meier, Jordan L, Merk, Daniel, Michel, Maurice, Morgan, Maxwell R, Mueller-Fahrnow, Anke, Owen, Dafydd R, Perry, Benjamin G, Rosenberg, Saul H, Saikatendu, Kumar Singh, Schapira, Matthieu, Scholten, Cora, Sharma, Sujata, Simeonov, Anton, Sundström, Michael, Superti-Furga, Giulio, Todd, Matthew H, Tredup, Claudia, Vedadi, Masoud, von Delft, Frank, Willson, Timothy M, Winter, Georg E, Workman, Paul, Arrowsmith, Cheryl H
Published in MedChemComm (27.01.2022)
Published in MedChemComm (27.01.2022)
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Journal Article
Abstract 14: Preclinical evaluation of novel HIF-1α/P300 binding inhibitors
Strope, Jonathan D., Harris, Emily M., Beedie, Shaunna L., Chau, Cindy H., Cook, Kristina M., Schofield, Christopher J., Gustafson, Kirk R., Figg, William D.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article