Exploring genomic alteration in pediatric cancer using ProteinPaint
Zhou, Xin, Edmonson, Michael N, Wilkinson, Mark R, Patel, Aman, Wu, Gang, Liu, Yu, Li, Yongjin, Zhang, Zhaojie, Rusch, Michael C, Parker, Matthew, Becksfort, Jared, Downing, James R, Zhang, Jinghui
Published in Nature genetics (01.01.2016)
Published in Nature genetics (01.01.2016)
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Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome
Rusch, Michael, Nakitandwe, Joy, Shurtleff, Sheila, Newman, Scott, Zhang, Zhaojie, Edmonson, Michael N., Parker, Matthew, Jiao, Yuannian, Ma, Xiaotu, Liu, Yanling, Gu, Jiali, Walsh, Michael F., Becksfort, Jared, Thrasher, Andrew, Li, Yongjin, McMurry, James, Hedlund, Erin, Patel, Aman, Easton, John, Yergeau, Donald, Vadodaria, Bhavin, Tatevossian, Ruth G., Raimondi, Susana, Hedges, Dale, Chen, Xiang, Hagiwara, Kohei, McGee, Rose, Robinson, Giles W., Klco, Jeffery M., Gruber, Tanja A., Ellison, David W., Downing, James R, Zhang, Jinghui
Published in Nature communications (27.09.2018)
Published in Nature communications (27.09.2018)
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A hybrid method of correcting CBCT for proton range estimation with deep learning and deformable image registration
Uh, Jinsoo, Wang, Chuang, Jordan, Jacob A, Pirlepesov, Fakhriddin, Becksfort, Jared B, Ates, Ozgur, Krasin, Matthew J, Hua, Chia-Ho
Published in Physics in medicine & biology (31.07.2023)
Published in Physics in medicine & biology (31.07.2023)
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Pediatric Cancer Variant Pathogenicity Information Exchange (PeCanPIE): a cloud-based platform for curating and classifying germline variants
Edmonson, Michael N, Patel, Aman N, Hedges, Dale J, Wang, Zhaoming, Rampersaud, Evadnie, Kesserwan, Chimene A, Zhou, Xin, Liu, Yanling, Newman, Scott, Rusch, Michael C, McLeod, Clay L, Wilkinson, Mark R, Rice, Stephen V, Soussi, Thierry, Taylor, J Paul, Benatar, Michael, Becksfort, Jared B, Nichols, Kim E, Robison, Leslie L, Downing, James R, Zhang, Jinghui
Published in Genome research (01.09.2019)
Published in Genome research (01.09.2019)
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Pre- and Posttherapy Risk Factors for Vasculopathy in Pediatric Patients With Craniopharyngioma Treated With Surgery and Proton Radiation Therapy
Lucas, John T., Faught, Austin M., Hsu, Chih Yang, Wilson, Lydia J., Guo, Yian, Li, Yimei, Khan, Raja, Becksfort, Jared B., LeVine, David A., Ismael, Yousef, Darrow, Kaleb, Moskvin, Vadim P., Pirlepesov, Fakhriddin, Klimo, Paul, Elijovich, Lucas, Indelicato, Daniel J., Boop, Fredrick A., Merchant, Thomas E.
Published in International journal of radiation oncology, biology, physics (01.05.2022)
Published in International journal of radiation oncology, biology, physics (01.05.2022)
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Revised clinical and molecular risk strata define the incidence and pattern of failure in medulloblastoma following risk-adapted radiotherapy and dose-intensive chemotherapy: results from a phase III multi-institutional study
Lucas, John T, Tinkle, Christopher L, Huang, Jie, Onar-Thomas, Arzu, Srinivasan, Sudharsan, Tumlin, Parker, Becksfort, Jared B, Klimo, Paul, Boop, Frederick A, Robinson, Giles W, Orr, Brent A, Harreld, Julie H, Krasin, Matthew J, Northcott, Paul A, Ellison, David W, Gajjar, Amar, Merchant, Thomas E
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2022)
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2022)
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Germline Mutations in Predisposition Genes in Pediatric Cancer
Zhang, Jinghui, Walsh, Michael F, Wu, Gang, Edmonson, Michael N, Gruber, Tanja A, Easton, John, Hedges, Dale, Ma, Xiaotu, Zhou, Xin, Yergeau, Donald A, Wilkinson, Mark R, Vadodaria, Bhavin, Chen, Xiang, McGee, Rose B, Hines-Dowell, Stacy, Nuccio, Regina, Quinn, Emily, Shurtleff, Sheila A, Rusch, Michael, Patel, Aman, Becksfort, Jared B, Wang, Shuoguo, Weaver, Meaghann S, Ding, Li, Mardis, Elaine R, Wilson, Richard K, Gajjar, Amar, Ellison, David W, Pappo, Alberto S, Pui, Ching-Hon, Nichols, Kim E, Downing, James R
Published in The New England journal of medicine (10.12.2015)
Published in The New England journal of medicine (10.12.2015)
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RB1 gene inactivation by chromothripsis in human retinoblastoma
McEvoy, Justina, Nagahawatte, Panduka, Finkelstein, David, Richards-Yutz, Jennifer, Valentine, Marcus, Ma, Jing, Mullighan, Charles, Song, Guangchun, Chen, Xiang, Wilson, Matthew, Brennan, Rachel, Pounds, Stanley, Becksfort, Jared, Huether, Robert, Lu, Charles, Fulton, Robert S, Fulton, Lucinda L, Hong, Xin, Dooling, David J, Ochoa, Kerri, Mardis, Elaine R, Wilson, Richard K, Easton, John, Zhang, Jinghui, Downing, James R, Ganguly, Arupa, Dyer, Michael A
Published in Oncotarget (30.01.2014)
Published in Oncotarget (30.01.2014)
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Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia
Ntziachristos, Panagiotis, Tsirigos, Aristotelis, Welstead, G. Grant, Trimarchi, Thomas, Bakogianni, Sofia, Xu, Luyao, Loizou, Evangelia, Holmfeldt, Linda, Strikoudis, Alexandros, King, Bryan, Mullenders, Jasper, Becksfort, Jared, Nedjic, Jelena, Paietta, Elisabeth, Tallman, Martin S., Rowe, Jacob M., Tonon, Giovanni, Satoh, Takashi, Kruidenier, Laurens, Prinjha, Rab, Akira, Shizuo, Van Vlierberghe, Pieter, Ferrando, Adolfo A., Jaenisch, Rudolf, Mullighan, Charles G., Aifantis, Iannis
Published in Nature (London) (23.10.2014)
Published in Nature (London) (23.10.2014)
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Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
GANG WU, BRONISCER, Alberto, JUNYUAN ZHANG, GAJJAR, Amar, DYER, Michael A, MULLIGHAN, Charles G, GILBERTSON, Richard J, MARDIS, Elaine R, WILSON, Richard K, DOWNING, James R, ELLISON, David W, JINGHUI ZHANG, MCEACHRON, Troy A, BAKER, Suzanne J, LU, Charles, PAUGH, Barbara S, BECKSFORT, Jared, CHUNXU QU, LI DING, HUETHER, Robert, PARKER, Matthew
Published in Nature genetics (01.03.2012)
Published in Nature genetics (01.03.2012)
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The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
Wu, Gang, Diaz, Alexander K, Paugh, Barbara S, Rankin, Sherri L, Ju, Bensheng, Li, Yongjin, Zhu, Xiaoyan, Qu, Chunxu, Chen, Xiang, Zhang, Junyuan, Easton, John, Edmonson, Michael, Ma, Xiaotu, Lu, Charles, Nagahawatte, Panduka, Hedlund, Erin, Rusch, Michael, Pounds, Stanley, Lin, Tong, Onar-Thomas, Arzu, Huether, Robert, Kriwacki, Richard, Parker, Matthew, Gupta, Pankaj, Becksfort, Jared, Wei, Lei, Mulder, Heather L, Boggs, Kristy, Vadodaria, Bhavin, Yergeau, Donald, Russell, Jake C, Ochoa, Kerri, Fulton, Robert S, Fulton, Lucinda L, Jones, Chris, Boop, Frederick A, Broniscer, Alberto, Wetmore, Cynthia, Gajjar, Amar, Ding, Li, Mardis, Elaine R, Wilson, Richard K, Taylor, Michael R, Downing, James R, Ellison, David W, Zhang, Jinghui, Baker, Suzanne J
Published in Nature genetics (01.05.2014)
Published in Nature genetics (01.05.2014)
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Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia
Roberts, Kathryn G, Li, Yongjin, Payne-Turner, Debbie, Harvey, Richard C, Yang, Yung-Li, Pei, Deqing, McCastlain, Kelly, Ding, Li, Lu, Charles, Song, Guangchun, Ma, Jing, Becksfort, Jared, Rusch, Michael, Chen, Shann-Ching, Easton, John, Cheng, Jinjun, Boggs, Kristy, Santiago-Morales, Natalia, Iacobucci, Ilaria, Fulton, Robert S, Wen, Ji, Valentine, Marcus, Cheng, Cheng, Paugh, Steven W, Devidas, Meenakshi, Chen, I-Ming, Reshmi, Shalini, Smith, Amy, Hedlund, Erin, Gupta, Pankaj, Nagahawatte, Panduka, Wu, Gang, Chen, Xiang, Yergeau, Donald, Vadodaria, Bhavin, Mulder, Heather, Winick, Naomi J, Larsen, Eric C, Carroll, William L, Heerema, Nyla A, Carroll, Andrew J, Grayson, Guy, Tasian, Sarah K, Moore, Andrew S, Keller, Frank, Frei-Jones, Melissa, Whitlock, James A, Raetz, Elizabeth A, White, Deborah L, Hughes, Timothy P, Guidry Auvil, Jaime M, Smith, Malcolm A, Marcucci, Guido, Bloomfield, Clara D, Mrózek, Krzysztof, Kohlschmidt, Jessica, Stock, Wendy, Kornblau, Steven M, Konopleva, Marina, Paietta, Elisabeth, Pui, Ching-Hon, Jeha, Sima, Relling, Mary V, Evans, William E, Gerhard, Daniela S, Gastier-Foster, Julie M, Mardis, Elaine, Wilson, Richard K, Loh, Mignon L, Downing, James R, Hunger, Stephen P, Willman, Cheryl L, Zhang, Jinghui, Mullighan, Charles G
Published in The New England journal of medicine (11.09.2014)
Published in The New England journal of medicine (11.09.2014)
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The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias
Andersson, Anna K, Ma, Jing, Wang, Jianmin, Chen, Xiang, Gedman, Amanda Larson, Dang, Jinjun, Nakitandwe, Joy, Holmfeldt, Linda, Parker, Matthew, Easton, John, Huether, Robert, Kriwacki, Richard, Rusch, Michael, Wu, Gang, Li, Yongjin, Mulder, Heather, Raimondi, Susana, Pounds, Stanley, Kang, Guolian, Shi, Lei, Becksfort, Jared, Gupta, Pankaj, Payne-Turner, Debbie, Vadodaria, Bhavin, Boggs, Kristy, Yergeau, Donald, Manne, Jayanthi, Song, Guangchun, Edmonson, Michael, Nagahawatte, Panduka, Wei, Lei, Cheng, Cheng, Pei, Deqing, Sutton, Rosemary, Venn, Nicola C, Chetcuti, Albert, Rush, Amanda, Catchpoole, Daniel, Heldrup, Jesper, Fioretos, Thoas, Lu, Charles, Ding, Li, Pui, Ching-Hon, Shurtleff, Sheila, Mullighan, Charles G, Mardis, Elaine R, Wilson, Richard K, Gruber, Tanja A, Zhang, Jinghui, Downing, James R
Published in Nature genetics (01.04.2015)
Published in Nature genetics (01.04.2015)
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C11orf95–RELA fusions drive oncogenic NF-κB signalling in ependymoma
Parker, Matthew, Mohankumar, Kumarasamypet M., Punchihewa, Chandanamali, Weinlich, Ricardo, Dalton, James D., Li, Yongjin, Lee, Ryan, Tatevossian, Ruth G., Phoenix, Timothy N., Thiruvenkatam, Radhika, White, Elsie, Tang, Bo, Orisme, Wilda, Gupta, Kirti, Rusch, Michael, Chen, Xiang, Li, Yuxin, Nagahawhatte, Panduka, Hedlund, Erin, Finkelstein, David, Wu, Gang, Shurtleff, Sheila, Easton, John, Boggs, Kristy, Yergeau, Donald, Vadodaria, Bhavin, Mulder, Heather L., Becksfort, Jared, Gupta, Pankaj, Huether, Robert, Ma, Jing, Song, Guangchun, Gajjar, Amar, Merchant, Thomas, Boop, Frederick, Smith, Amy A., Ding, Li, Lu, Charles, Ochoa, Kerri, Zhao, David, Fulton, Robert S., Fulton, Lucinda L., Mardis, Elaine R., Wilson, Richard K., Downing, James R., Green, Douglas R., Zhang, Jinghui, Ellison, David W., Gilbertson, Richard J.
Published in Nature (London) (27.02.2014)
Published in Nature (London) (27.02.2014)
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Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology
Qaddoumi, Ibrahim, Orisme, Wilda, Wen, Ji, Santiago, Teresa, Gupta, Kirti, Dalton, James D., Tang, Bo, Haupfear, Kelly, Punchihewa, Chandanamali, Easton, John, Mulder, Heather, Boggs, Kristy, Shao, Ying, Rusch, Michael, Becksfort, Jared, Gupta, Pankaj, Wang, Shuoguo, Lee, Ryan P., Brat, Daniel, Peter Collins, V., Dahiya, Sonika, George, David, Konomos, William, Kurian, Kathreena M., McFadden, Kathryn, Serafini, Luciano Neder, Nickols, Hilary, Perry, Arie, Shurtleff, Sheila, Gajjar, Amar, Boop, Fredrick A., Klimo, Paul D., Mardis, Elaine R., Wilson, Richard K., Baker, Suzanne J., Zhang, Jinghui, Wu, Gang, Downing, James R., Tatevossian, Ruth G., Ellison, David W.
Published in Acta neuropathologica (01.06.2016)
Published in Acta neuropathologica (01.06.2016)
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Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas
Zhang, Jinghui, Wu, Gang, Miller, Claudia P, Tatevossian, Ruth G, Dalton, James D, Tang, Bo, Orisme, Wilda, Punchihewa, Chandanamali, Parker, Matthew, Qaddoumi, Ibrahim, Boop, Fredrick A, Lu, Charles, Kandoth, Cyriac, Ding, Li, Lee, Ryan, Huether, Robert, Chen, Xiang, Hedlund, Erin, Nagahawatte, Panduka, Rusch, Michael, Boggs, Kristy, Cheng, Jinjun, Becksfort, Jared, Ma, Jing, Song, Guangchun, Li, Yongjin, Wei, Lei, Wang, Jianmin, Shurtleff, Sheila, Easton, John, Zhao, David, Fulton, Robert S, Fulton, Lucinda L, Dooling, David J, Vadodaria, Bhavin, Mulder, Heather L, Tang, Chunlao, Ochoa, Kerri, Mullighan, Charles G, Gajjar, Amar, Kriwacki, Richard, Sheer, Denise, Gilbertson, Richard J, Mardis, Elaine R, Wilson, Richard K, Downing, James R, Baker, Suzanne J, Ellison, David W
Published in Nature genetics (01.06.2013)
Published in Nature genetics (01.06.2013)
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Outcomes of children with BCR-ABL1–like acute lymphoblastic leukemia treated with risk-directed therapy based on the levels of minimal residual disease
Roberts, Kathryn G, Pei, Deqing, Campana, Dario, Payne-Turner, Debbie, Li, Yongjin, Cheng, Cheng, Sandlund, John T, Jeha, Sima, Easton, John, Becksfort, Jared, Zhang, Jinghui, Coustan-Smith, Elaine, Raimondi, Susana C, Leung, Wing H, Relling, Mary V, Evans, William E, Downing, James R, Mullighan, Charles G, Pui, Ching-Hon
Published in Journal of clinical oncology (20.09.2014)
Published in Journal of clinical oncology (20.09.2014)
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Journal Article
The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes
Huether, Robert, Dong, Li, Chen, Xiang, Wu, Gang, Parker, Matthew, Wei, Lei, Ma, Jing, Edmonson, Michael N., Hedlund, Erin K., Rusch, Michael C., Shurtleff, Sheila A., Mulder, Heather L., Boggs, Kristy, Vadordaria, Bhavin, Cheng, Jinjun, Yergeau, Donald, Song, Guangchun, Becksfort, Jared, Lemmon, Gordon, Weber, Catherine, Cai, Zhongling, Dang, Jinjun, Walsh, Michael, Gedman, Amanda L., Faber, Zachary, Easton, John, Gruber, Tanja, Kriwacki, Richard W., Partridge, Janet F., Ding, Li, Wilson, Richard K., Mardis, Elaine R., Mullighan, Charles G., Gilbertson, Richard J., Baker, Suzanne J., Zambetti, Gerard, Ellison, David W., Zhang, Jinghui, Downing, James R.
Published in Nature communications (08.04.2014)
Published in Nature communications (08.04.2014)
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Association of Age at Diagnosis and Genetic Mutations in Patients With Neuroblastoma
Cheung, Nai-Kong V, Zhang, Jinghui, Lu, Charles, Parker, Matthew, Bahrami, Armita, Tickoo, Satish K, Heguy, Adriana, Pappo, Alberto S, Federico, Sara, Dalton, James, Cheung, Irene Y, Ding, Li, Fulton, Robert, Wang, Jianmin, Chen, Xiang, Becksfort, Jared, Wu, Jianrong, Billups, Catherine A, Ellison, David, Mardis, Elaine R, Wilson, Richard K, Downing, James R, Dyer, Michael A, St Jude Children's Research Hospital–Washington University Pediatric Cancer Genome Project, for the
Published in JAMA : the journal of the American Medical Association (14.03.2012)
Published in JAMA : the journal of the American Medical Association (14.03.2012)
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Journal Article
Novel mutations target distinct subgroups of medulloblastoma
Robinson, Giles, Parker, Matthew, Kranenburg, Tanya A., Lu, Charles, Chen, Xiang, Ding, Li, Phoenix, Timothy N., Hedlund, Erin, Wei, Lei, Zhu, Xiaoyan, Chalhoub, Nader, Baker, Suzanne J., Huether, Robert, Kriwacki, Richard, Curley, Natasha, Thiruvenkatam, Radhika, Wang, Jianmin, Wu, Gang, Rusch, Michael, Hong, Xin, Becksfort, Jared, Gupta, Pankaj, Ma, Jing, Easton, John, Vadodaria, Bhavin, Onar-Thomas, Arzu, Lin, Tong, Li, Shaoyi, Pounds, Stanley, Paugh, Steven, Zhao, David, Kawauchi, Daisuke, Roussel, Martine F., Finkelstein, David, Ellison, David W., Lau, Ching C., Bouffet, Eric, Hassall, Tim, Gururangan, Sridharan, Cohn, Richard, Fulton, Robert S., Fulton, Lucinda L., Dooling, David J., Ochoa, Kerri, Gajjar, Amar, Mardis, Elaine R., Wilson, Richard K., Downing, James R., Zhang, Jinghui, Gilbertson, Richard J.
Published in Nature (London) (02.08.2012)
Published in Nature (London) (02.08.2012)
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