Structural characterisation of Tpx from Yersinia pseudotuberculosis reveals insights into the binding of salicylidene acylhydrazide compounds
Gabrielsen, Mads, Beckham, Katherine S H, Feher, Victoria A, Zetterström, Caroline E, Wang, Dai, Müller, Sylke, Elofsson, Mikael, Amaro, Rommie E, Byron, Olwyn, Roe, Andrew J
Published in PloS one (27.02.2012)
Published in PloS one (27.02.2012)
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Journal Article
Structure of the mycobacterial ESX-5 type VII secretion system pore complex
Beckham, Katherine S H, Ritter, Christina, Chojnowski, Grzegorz, Ziemianowicz, Daniel S, Mullapudi, Edukondalu, Rettel, Mandy, Savitski, Mikhail M, Mortensen, Simon A, Kosinski, Jan, Wilmanns, Matthias
Published in Science advances (01.06.2021)
Published in Science advances (01.06.2021)
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Journal Article
Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis
Beckham, Katherine S. H., Ciccarelli, Luciano, Bunduc, Catalin M., Mertens, Haydyn D. T., Ummels, Roy, Lugmayr, Wolfgang, Mayr, Julia, Rettel, Mandy, Savitski, Mikhail M., Svergun, Dmitri I., Bitter, Wilbert, Wilmanns, Matthias, Marlovits, Thomas C., Parret, Annabel H. A., Houben, Edith N. G.
Published in Nature microbiology (10.04.2017)
Published in Nature microbiology (10.04.2017)
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Journal Article
Express your LOV: an engineered flavoprotein as a reporter for protein expression and purification
Gawthorne, Jayde A, Reddick, L Evan, Akpunarlieva, Snezhana N, Beckham, Katherine S H, Christie, John M, Alto, Neal M, Gabrielsen, Mads, Roe, Andrew J
Published in PloS one (27.12.2012)
Published in PloS one (27.12.2012)
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Journal Article
Signal regulatory protein alpha (SIRPα) regulates the homeostasis of CD103+CD11b+ DCs in the intestinal lamina propria
Scott, Charlotte L., Zangerle Murray, Tamsin F. P., Beckham, Katherine S. H., Douce, Gillian, Mowat, Allan McI
Published in European journal of immunology (01.12.2014)
Published in European journal of immunology (01.12.2014)
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Journal Article
The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7
Beckham, Katherine S. H., Connolly, James P. R., Ritchie, Jennifer M., Wang, Dai, Gawthorne, Jayde A., Tahoun, Amin, Gally, David L., Burgess, Karl, Burchmore, Richard J., Smith, Brian O., Beatson, Scott A., Byron, Olwyn, Wolfe, Alan J., Douce, Gillian R., Roe, Andrew J.
Published in Molecular microbiology (01.07.2014)
Published in Molecular microbiology (01.07.2014)
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Journal Article
The structure of an orthorhombic crystal form of a `forced reduced' thiol peroxidase reveals lattice formation aided by the presence of the affinity tag
Beckham, Katherine S. H., Byron, Olwyn, Roe, Andrew J., Gabrielsen, Mads
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.05.2012)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.05.2012)
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Journal Article
FolX from Pseudomonas aeruginosa is octameric in both crystal and solution
Gabrielsen, Mads, Beckham, Katherine S.H., Cogdell, Richard J., Byron, Olwyn, Roe, Andrew J.
Published in FEBS letters (24.04.2012)
Published in FEBS letters (24.04.2012)
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Journal Article
An NAD+ Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death
Freire, Diana Mendes, Gutierrez, Claude, Garza-Garcia, Acely, Grabowska, Anna D., Sala, Ambre J., Ariyachaokun, Kanchiyaphat, Panikova, Terezie, Beckham, Katherine S.H., Colom, André, Pogenberg, Vivian, Cianci, Michele, Tuukkanen, Anne, Boudehen, Yves-Marie, Peixoto, Antonio, Botella, Laure, Svergun, Dmitri I., Schnappinger, Dirk, Schneider, Thomas R., Genevaux, Pierre, de Carvalho, Luiz Pedro Sorio, Wilmanns, Matthias, Parret, Annabel H.A., Neyrolles, Olivier
Published in Molecular cell (21.03.2019)
Published in Molecular cell (21.03.2019)
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Journal Article
Identification of Bacterial Target Proteins for the Salicylidene Acylhydrazide Class of Virulence-blocking Compounds
Wang, Dai, Zetterström, Caroline E., Gabrielsen, Mads, Beckham, Katherine S.H., Tree, Jai J., Macdonald, Sarah E., Byron, Olwyn, Mitchell, Tim J., Gally, David L., Herzyk, Pawel, Mahajan, Arvind, Uvell, Hanna, Burchmore, Richard, Smith, Brian O., Elofsson, Mikael, Roe, Andrew J.
Published in The Journal of biological chemistry (26.08.2011)
Published in The Journal of biological chemistry (26.08.2011)
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Journal Article
C25-modified rifamycin derivatives with improved activity against Mycobacterium abscessus
Paulowski, Laura, Beckham, Katherine S H, Johansen, Matt D, Berneking, Laura, Van, Nhi, Degefu, Yonatan, Staack, Sonja, Sotomayor, Flor Vasquez, Asar, Lucia, Rohde, Holger, Aldridge, Bree B, Aepfelbacher, Martin, Parret, Annabel, Wilmanns, Matthias, Kremer, Laurent, Combrink, Keith, Maurer, Florian P
Published in PNAS nexus (01.09.2022)
Published in PNAS nexus (01.09.2022)
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Journal Article
Expression, purification, crystallization and initial X-ray diffraction analysis of thiol peroxidase from Yersinia pseudotuberculosis
Gabrielsen, Mads, Zetterström, Caroline E., Wang, Dai, Beckham, Katherine S. H., Elofsson, Mikael, Isaacs, Neil W., Roe, Andrew J.
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.12.2010)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.12.2010)
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Journal Article
Crystal structures of WrbA, a spurious target of the salicylidene acylhydrazide inhibitors of type III secretion in Gram-negative pathogens, and verification of improved specificity of next-generation compounds
Zambelloni, Riccardo, Beckham, Katherine S.H., Wu, Hong-Jin, Elofsson, Mikael, Marquez, Rudi, Gabrielsen, Mads, Roe, Andrew J.
Published in Microbiology (Society for General Microbiology) (2022)
Published in Microbiology (Society for General Microbiology) (2022)
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Journal Article
Signal regulatory protein alpha (SIRPα) regulates the homeostasis of CD103 + CD11b + DC s in the intestinal lamina propria
Scott, Charlotte L., Zangerle Murray, Tamsin F. P., Beckham, Katherine S. H., Douce, Gillian, Mowat, Allan McI
Published in European journal of immunology (01.12.2014)
Published in European journal of immunology (01.12.2014)
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Journal Article
The metabolic enzyme AdhE controls the virulence of E scherichia coli O 157: H 7
Beckham, Katherine S. H., Connolly, James P. R., Ritchie, Jennifer M., Wang, Dai, Gawthorne, Jayde A., Tahoun, Amin, Gally, David L., Burgess, Karl, Burchmore, Richard J., Smith, Brian O., Beatson, Scott A., Byron, Olwyn, Wolfe, Alan J., Douce, Gillian R., Roe, Andrew J.
Published in Molecular microbiology (01.07.2014)
Published in Molecular microbiology (01.07.2014)
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Journal Article
The metabolic enzyme AdhE controls the virulence of Escherichia coliO157:H7
Beckham, Katherine SH, Connolly, James PR, Ritchie, Jennifer M, Wang, Dai, Gawthorne, Jayde A, Tahoun, Amin, Gally, David L, Burgess, Karl, Burchmore, Richard J, Smith, Brian O, Beatson, Scott A, Byron, Olwyn, Wolfe, Alan J, Douce, Gillian R, Roe, Andrew J
Published in Molecular microbiology (2014)
Published in Molecular microbiology (2014)
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Journal Article