Protein-Based Adjuvants for Vaccines as Immunomodulators of the Innate and Adaptive Immune Response: Current Knowledge, Challenges, and Future Opportunities
Díaz-Dinamarca, Diego A, Salazar, Michelle L, Castillo, Byron N, Manubens, Augusto, Vasquez, Abel E, Salazar, Fabián, Becker, María Inés
Published in Pharmaceutics (11.08.2022)
Published in Pharmaceutics (11.08.2022)
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Journal Article
Immunotherapeutic Potential of Mollusk Hemocyanins in Combination with Human Vaccine Adjuvants in Murine Models of Oral Cancer
Lladser, Alvaro, Manubens, Augusto, Becker, María Inés, Ferreira, Jorge, Jara, Lilian, Venuti, Aldo, Curzio, Gianfranca, Paolini, Francesca, Villar, Javiera, Del Campo, Miguel, Mora Román, Juan José, Murgas, Paola
Published in Journal of immunology research (01.01.2019)
Published in Journal of immunology research (01.01.2019)
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Journal Article
Surface immunogenic protein from Streptococcus agalactiae and Fissurella latimarginata hemocyanin are TLR4 ligands and activate MyD88- and TRIF dependent signaling pathways
Díaz-Dinamarca, Diego A., Salazar, Michelle L., Escobar, Daniel F., Castillo, Byron N., Valdebenito, Bastián, Díaz, Pablo, Manubens, Augusto, Salazar, Fabián, Troncoso, Mayarling F., Lavandero, Sergio, Díaz, Janepsy, Becker, María Inés, Vásquez, Abel E.
Published in Frontiers in immunology (18.09.2023)
Published in Frontiers in immunology (18.09.2023)
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Journal Article
A novel immunomodulatory hemocyanin from the limpet Fissurella latimarginata promotes potent anti-tumor activity in melanoma
Arancibia, Sergio, Espinoza, Cecilia, Salazar, Fabián, Del Campo, Miguel, Tampe, Ricardo, Zhong, Ta-Ying, De Ioannes, Pablo, Moltedo, Bruno, Ferreira, Jorge, Lavelle, Ed C, Manubens, Augusto, De Ioannes, Alfredo E, Becker, María Inés
Published in PloS one (23.01.2014)
Published in PloS one (23.01.2014)
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Journal Article
Enhanced structural stability of Concholepas hemocyanin increases its immunogenicity and maintains its non‐specific immunostimulatory effects
Arancibia, Sergio, Campo, Miguel Del, Nova, Esteban, Salazar, Fabián, Becker, María Inés
Published in European journal of immunology (01.03.2012)
Published in European journal of immunology (01.03.2012)
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Journal Article
A heat-shocked melanoma cell lysate vaccine enhances tumor infiltration by prototypic effector T cells inhibiting tumor growth
Gleisner, María Alejandra, Pereda, Cristián, Tittarelli, Andrés, Navarrete, Mariela, Fuentes, Camila, Ávalos, Ignacio, Tempio, Fabian, Araya, Juan Pablo, Becker, María Inés, González, Fermín Eduardo, López, Mercedes Natalia, Salazar-Onfray, Flavio
Published in Journal for immunotherapy of cancer (01.07.2020)
Published in Journal for immunotherapy of cancer (01.07.2020)
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Journal Article
TLR4, but Neither Dectin-1 nor Dectin-2, Participates in the Mollusk Hemocyanin-Induced Proinflammatory Effects in Antigen-Presenting Cells From Mammals
Jiménez, José M, Salazar, Michelle L, Arancibia, Sergio, Villar, Javiera, Salazar, Fabián, Brown, Gordon D, Lavelle, Ed C, Martínez-Pomares, Luisa, Ortiz-Quintero, Jafet, Lavandero, Sergio, Manubens, Augusto, Becker, María Inés
Published in Frontiers in immunology (31.05.2019)
Published in Frontiers in immunology (31.05.2019)
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Journal Article
Immunotherapeutic effect of Concholepas hemocyanin in the murine bladder cancer model: evidence for conserved antitumor properties among hemocyanins
Moltedo, Bruno, Faunes, Fernando, Haussmann, Denise, De Ioannes, Pablo, De Ioannes, Alfredo E, Puente, Javier, Becker, María Inés
Published in The Journal of urology (01.12.2006)
Published in The Journal of urology (01.12.2006)
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Journal Article
Allergens of the urushiol family promote mitochondrial dysfunction by inhibiting the electron transport at the level of cytochromes b and chemically modify cytochrome c1
Pacheco, Rodrigo, Quezada, Sergio A, Kalergis, Alexis M, Becker, María Inés, Ferreira, Jorge, De Ioannes, Alfredo E
Published in Biological research (28.10.2021)
Published in Biological research (28.10.2021)
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Journal Article
N-Glycosylation of mollusk hemocyanins contributes to their structural stability and immunomodulatory properties in mammals
Salazar, Michelle L., Jimènez, Josè M., Villar, Javiera, Rivera, Maira, Báez, Mauricio, Manubens, Augusto, Becker, María Inès
Published in The Journal of biological chemistry (20.12.2019)
Published in The Journal of biological chemistry (20.12.2019)
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Journal Article
Immunopurification of Golgi vesicles by magnetic sorting
Mura, Casilda V, Becker, Marı́a Inés, Orellana, Ariel, Wolff, Daniel
Published in Journal of immunological methods (01.02.2002)
Published in Journal of immunological methods (01.02.2002)
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Journal Article
Antiproliferative and Uncoupling Effects of Delocalized, Lipophilic, Cationic Gallic Acid Derivatives on Cancer Cell Lines. Validation in Vivo in Singenic Mice
Jara, José A, Castro-Castillo, Vicente, Saavedra-Olavarría, Jorge, Peredo, Liliana, Pavanni, Mario, Jaña, Fabián, Letelier, María Eugenia, Parra, Eduardo, Becker, María Inés, Morello, Antonio, Kemmerling, Ulrike, Maya, Juan Diego, Ferreira, Jorge
Published in Journal of medicinal chemistry (27.03.2014)
Published in Journal of medicinal chemistry (27.03.2014)
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Journal Article
Recombinant Surface Immunogenic Protein from S. agalactiae and hemocyanin from Fisurella latimarginata promote cross-presentation dependence on the TLR-4 signaling
Diaz-Dinamarca, Diego A, Salazar, Michelle, Manubens, Augusto, Salazar, Fabián, Troncoso, Mayarling F, Lavandero, Sergio, Diaz, Janepsy, Vasquez, Abel E, Becker, María Inés
Published in The Journal of immunology (1950) (01.05.2023)
Published in The Journal of immunology (1950) (01.05.2023)
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Journal Article
Oxidative Modifications in Crystallin Proteins and Lens Epithelial Cells Associated with Photosensitized Reactions Mediated by the Major Chromophore Arising from Glucose Degradation
Vargas, Francisco, Becker, María Inés, Friguet, Bertrand, Silva, Eduardo, Ávila, Felipe
Published in Journal of the Brazilian Chemical Society (01.02.2016)
Published in Journal of the Brazilian Chemical Society (01.02.2016)
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Immunocompetence of breeding females is sensitive to cortisol levels but not to communal rearing in the degu ( Octodon degus )
Ebensperger, Luis A, León, Cecilia, Ramírez-Estrada, Juan, Abades, Sebastian, Hayes, Loren D, Nova, Esteban, Salazar, Fabián, Bhattacharjee, Joydeep, Becker, María Inés
Published in Physiology & behavior (01.03.2015)
Published in Physiology & behavior (01.03.2015)
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Journal Article
Mechanisms underlying the mollusk hemocyanin processing and presentation through MHC-dependent pathways in antigen presenting cells of mammals
Becker, María Inés, Salazar, Michelle L, Díaz-Dinamarca, Diego, Vásquez, Abel E, Villar, Javiera, Alvarado, Alejandra, Castillo, Byron, Navarro, Daniel, Salazar, Fabián, Manubens, Augusto
Published in The Journal of immunology (1950) (01.05.2022)
Published in The Journal of immunology (1950) (01.05.2022)
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Journal Article
Concholepas hemocyanin biosynthesis takes place in the hepatopancreas, with hemocytes being involved in its metabolism
Manubens, Augusto, Salazar, Fabián, Haussmann, Denise, Figueroa, Jaime, Del Campo, Miguel, Pinto, Jonathan Martínez, Huaquín, Laura, Venegas, Alejandro, Becker, María Inés
Published in Cell and tissue research (01.12.2010)
Published in Cell and tissue research (01.12.2010)
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Journal Article
Immunodominant role of CCHA subunit of Concholepas hemocyanin is associated with unique biochemical properties
Becker, María Inés, Fuentes, Alejandra, Del Campo, Miguel, Manubens, Augusto, Nova, Esteban, Oliva, Harold, Faunes, Fernando, Valenzuela, María Antonieta, Campos-Vallette, Marcelo, Aliaga, Alvaro, Ferreira, Jorge, De Ioannes, Alfredo E., De Ioannes, Pablo, Moltedo, Bruno
Published in International immunopharmacology (01.03.2009)
Published in International immunopharmacology (01.03.2009)
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