A scalable and operationally simple radical trifluoromethylation
Beatty, Joel W., Douglas, James J., Cole, Kevin P., Stephenson, Corey R. J.
Published in Nature communications (10.08.2015)
Published in Nature communications (10.08.2015)
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Journal Article
Visible Light-Mediated Decarboxylative Alkylation of Pharmaceutically Relevant Heterocycles
Sun, Alexandra C, McClain, Edward J, Beatty, Joel W, Stephenson, Corey R. J
Published in Organic letters (15.06.2018)
Published in Organic letters (15.06.2018)
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Journal Article
Radical Chlorodifluoromethylation: Providing a Motif for (Hetero)arene Diversification
McAtee, Rory C, Beatty, Joel W, McAtee, Christopher C, Stephenson, Corey R. J
Published in Organic letters (15.06.2018)
Published in Organic letters (15.06.2018)
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Journal Article
Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73
Beatty, Joel W, Lindsey, Erick A, Thomas-Tran, Rhiannon, Debien, Laurent, Mandal, Debashis, Jeffrey, Jenna L, Tran, Anh T, Fournier, Jeremy, Jacob, Steven D, Yan, Xuelei, Drew, Samuel L, Ginn, Elaine, Chen, Ada, Pham, Amber T, Zhao, Sharon, Jin, Lixia, Young, Stephen W, Walker, Nigel P, Leleti, Manmohan Reddy, Moschütz, Susanne, Sträter, Norbert, Powers, Jay P, Lawson, Kenneth V
Published in Journal of medicinal chemistry (23.04.2020)
Published in Journal of medicinal chemistry (23.04.2020)
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Journal Article
Discovery of Potent and Selective PI3Kγ Inhibitors
Drew, Samuel L, Thomas-Tran, Rhiannon, Beatty, Joel W, Fournier, Jeremy, Lawson, Kenneth V, Miles, Dillon H, Mata, Guillaume, Sharif, Ehesan U, Yan, Xuelei, Mailyan, Artur K, Ginn, Elaine, Chen, Jie, Wong, Kent, Soni, Divyank, Dhanota, Puja, Chen, Pei-Yu, Shaqfeh, Stefan G, Meleza, Cesar, Pham, Amber T, Chen, Ada, Zhao, Xiaoning, Banuelos, Jesus, Jin, Lixia, Schindler, Ulrike, Walters, Matthew J, Young, Stephen W, Walker, Nigel P, Leleti, Manmohan Reddy, Powers, Jay P, Jeffrey, Jenna L
Published in Journal of medicinal chemistry (08.10.2020)
Published in Journal of medicinal chemistry (08.10.2020)
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Journal Article
Design, Synthesis, and Structure-Activity Relationship Optimization of Pyrazolopyrimidine Amide Inhibitors of Phosphoinositide 3-Kinase γ (PI3Kγ)
Mata, Guillaume, Miles, Dillon H, Drew, Samuel L, Fournier, Jeremy, Lawson, Kenneth V, Mailyan, Artur K, Sharif, Ehesan U, Yan, Xuelei, Beatty, Joel W, Banuelos, Jesus, Chen, Jie, Ginn, Elaine, Chen, Ada, Gerrick, Kimberline Y, Pham, Amber T, Wong, Kent, Soni, Divyank, Dhanota, Puja, Shaqfeh, Stefan G, Meleza, Cesar, Narasappa, Nell, Singh, Hema, Zhao, Xiaoning, Jin, Lixia, Schindler, Ulrike, Walters, Matthew J, Young, Stephen W, Walker, Nigel P, Leleti, Manmohan Reddy, Powers, Jay P, Jeffrey, Jenna L
Published in Journal of medicinal chemistry (27.01.2022)
Published in Journal of medicinal chemistry (27.01.2022)
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Abstract 1206: Discovery and characterization of AB521, a novel, potent, and selective hypoxia-inducible factor (HIF)-2α inhibitor
Lawson, Kenneth V., Gauthier, Kelsey E. Sivick, Mailyan, Artur K., Fournier, Jeremy T., Beatty, Joel W., Drew, Samuel L., Kalisiak, Jarek, Gal, Balint, Mata, Guillaume, Wang, Zhang, Yan, Xuelei, Jin, Lixia, Ginn, Elaine, Piovesan, Dana, Au, Jennifer, Meleza, Cesar A., Young, Stephen W., Walters, Matthew J., Leleti, Manmohan, Powers, Jay P.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract P206: AB521 potently and selectively inhibits pro-tumorigenic gene transcription by Hypoxia-Inducible Factor (HIF)-2α in vitro and in vivo
Gauthier, Kelsey E. Sivick, Piovesan, Dana, Cho, Soonweng, Lawson, Kenneth V., Schweickert, Patrick G., Lopez, Alejandra, Liu, Suan, Park, Timothy, Mailyan, Artur, Fournier, Jeremy T. A., Beatty, Joel W., Drew, Samuel L., Kalisiak, Jarek, Gal, Balint, Mata, Guillaume, Wang, Zhang, Rosen, Brandon R., Hardman, Clayton, Epplin, Matthaw P., Yu, Kai, Haelsig, Karl T., Jin, Lixia, Ginn, Elaine, Au, Jennie, Meleza, Cesar A., Tencer, Joel, Pham, Amber, Kwon, Hyock J., Young, Stephen W., Leleti, Manmohan, Powers, Jay P., Walters, Matthew J.
Published in Molecular cancer therapeutics (01.12.2021)
Published in Molecular cancer therapeutics (01.12.2021)
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