Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting
Bear, Adham S., Blanchard, Tatiana, Cesare, Joseph, Ford, Michael J., Richman, Lee P., Xu, Chong, Baroja, Miren L., McCuaig, Sarah, Costeas, Christina, Gabunia, Khatuna, Scholler, John, Posey, Avery D., O’Hara, Mark H., Smole, Anze, Powell, Daniel J., Garcia, Benjamin A., Vonderheide, Robert H., Linette, Gerald P., Carreno, Beatriz M.
Published in Nature communications (16.07.2021)
Published in Nature communications (16.07.2021)
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Journal Article
Elimination of metastatic melanoma using gold nanoshell-enabled photothermal therapy and adoptive T cell transfer
Bear, Adham S, Kennedy, Laura C, Young, Joseph K, Perna, Serena K, Mattos Almeida, Joao Paulo, Lin, Adam Y, Eckels, Phillip C, Drezek, Rebekah A, Foster, Aaron E
Published in PloS one (23.07.2013)
Published in PloS one (23.07.2013)
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Journal Article
Facts and Hopes in Immunotherapy Strategies Targeting Antigens Derived from KRAS Mutations
Linette, Gerald P, Bear, Adham S, Carreno, Beatriz M
Published in Clinical cancer research (15.05.2024)
Published in Clinical cancer research (15.05.2024)
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Journal Article
Expression of inducible factors reprograms CAR-T cells for enhanced function and safety
Smole, Anže, Benton, Alexander, Poussin, Mathilde A., Eiva, Monika A., Mezzanotte, Claudia, Camisa, Barbara, Greco, Beatrice, Sharma, Prannda, Minutolo, Nicholas G., Gray, Falon, Bear, Adham S., Baroja, Miren L., Cummins, Casey, Xu, Chong, Sanvito, Francesca, Goldgewicht, Andrea Lang, Blanchard, Tatiana, Rodriguez-Garcia, Alba, Klichinsky, Michael, Bonini, Chiara, June, Carl H., Posey, Avery D., Linette, Gerald P., Carreno, Beatriz M., Casucci, Monica, Powell, Daniel J.
Published in Cancer cell (12.12.2022)
Published in Cancer cell (12.12.2022)
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Journal Article
T cells enhance gold nanoparticle delivery to tumors in vivo
Kennedy, Laura C, Bear, Adham S, Young, Joseph K, Lewinski, Nastassja A, Kim, Jean, Foster, Aaron E, Drezek, Rebekah A
Published in Nanoscale research letters (04.04.2011)
Published in Nanoscale research letters (04.04.2011)
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Journal Article
Replication-Competent Retroviruses in Gene-Modified T Cells Used in Clinical Trials: Is It Time to Revise the Testing Requirements?
Bear, Adham S, Morgan, Richard A, Cornetta, Kenneth, June, Carl H, Binder-Scholl, Gwendolyn, Dudley, Mark E, Feldman, Steven A, Rosenberg, Steven A, Shurtleff, Sheila A, Rooney, Cliona M, Heslop, Helen E, Dotti, Gianpietro
Published in Molecular therapy (01.02.2012)
Published in Molecular therapy (01.02.2012)
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Journal Article
Adoptive Cellular Therapy for Solid Tumors
Bear, Adham S, Fraietta, Joseph A, Narayan, Vivek K, O'Hara, Mark, Haas, Naomi B
Published in American Society of Clinical Oncology educational book (01.03.2021)
Published in American Society of Clinical Oncology educational book (01.03.2021)
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Journal Article
T Cells as Vehicles for Cancer Vaccination
Bear, Adham S., Cruz, Conrad R., Foster, Aaron E.
Published in BioMed research international (01.01.2011)
Published in BioMed research international (01.01.2011)
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Journal Article
Low rate of infusional toxicity after expanded cord blood transplantation
Bear, Adham S, Hanley, Patrick J, Bosque, Doyle M, Cruz, Conrad R, Kaur, Indresh, Liu, Hao, Kebriaei, Partow, Hosing, Chitra, Rezvani, Katayoun, Oran, Betul, De Lima, Marcos J, Bollard, Catherine M, Shpall, Elizabeth J
Published in Cytotherapy (Oxford, England) (01.08.2014)
Published in Cytotherapy (Oxford, England) (01.08.2014)
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Journal Article
Abstract 1899: Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting
Bear, Adham S., Blanchard, Tatiana, O'Hara, Mark H., Scholler, John, Vonderheide, Robert H., Linette, Gerald P., Carreno, Beatriz M.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract B04: Identification of T-cell receptors targeting mutant KRAS in pancreatic cancer
Bear, Adham S., Rech, Andrew J., Richman, Lee P., O'Hara, Mark H., Linette, Gerald P., Carreno, Beatriz M., Vonderheide, Robert H.
Published in Cancer research (Chicago, Ill.) (15.12.2019)
Published in Cancer research (Chicago, Ill.) (15.12.2019)
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Journal Article
Abstract PR08: TCR1020 specific for KRAS G12V restricted to HLA-A11:01 exhibits potent and precise antigen specificity for clinical development
Bear, Adham S., Nadler, Rebecca B., Scholler, John, Vonderheide, Robert H., Linette, Gerald P., Carreno, Beatriz M.
Published in Molecular cancer research (01.05.2023)
Published in Molecular cancer research (01.05.2023)
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Journal Article
Abstract PR019: Mutant KRAS-specific T cell receptors directed against prevalent G12D and G12V variants exhibit potent cytotoxic activity and CD8 co-receptor independence
Bear, Adham S., Nadler, Rebecca B., Scholler, John, Vonderheide, Robert H., Linette, Gerald P., Carreno, Beatriz M.
Published in Cancer research (Chicago, Ill.) (15.11.2022)
Published in Cancer research (Chicago, Ill.) (15.11.2022)
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Journal Article
Natural TCRs targeting KRASG12V display fine specificity and sensitivity to human solid tumors
Bear, Adham S, Nadler, Rebecca B, O'Hara, Mark H, Stanton, Kelsey L, Xu, Chong, Saporito, Robert J, Rech, Andrew J, Baroja, Miren L, Blanchard, Tatiana, Elliott, Maxwell H, d, Michael J, Jones, Richard C, Patel, Shivang, Brennan, Andrea L, O'Neil, Zachary, Powell, Daniel J, Vonderheide, Robert H, Linette, Gerald P, Carreno, Beatriz M
Published in The Journal of clinical investigation (17.09.2024)
Published in The Journal of clinical investigation (17.09.2024)
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Journal Article
Abstract A016: Phase 1 study of hypofractionated radiation in combination with tremelimumab and durvalumab in refractory metastatic pancreatic adenocarcinoma
O'Hara, Mark H., Bear, Adham S., Wattenberg, Max M., Teitelbaum, Ursina R., Reiss, Kim A., Karasic, Thomas B., Schneider, Charles J., O'Dwyer, Peter J., Ben-Josef, Edgar H., Wojcieszynski, Andrzej P., Maity, Amit H., Mick, Rosemarie H., Vonderheide, Robert H.
Published in Cancer research (Chicago, Ill.) (15.11.2022)
Published in Cancer research (Chicago, Ill.) (15.11.2022)
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Journal Article
Vaccination with ΔCD40L or Flagellin Gene-Modified T Cells Activates Dendritic Cells In Vivo and Induces a Potent Anti-Tumor Immune Response
Bear, Adham S, Turnis, Meghan M, Song, Xiao-Tong, Cruz, Russell, Lu, An, Gottschalk, Stephen, Rooney, Cliona M, Foster, Aaron E
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Journal Article