CDKN2A deletion remodels lipid metabolism to prime glioblastoma for ferroptosis
Minami, Jenna K., Morrow, Danielle, Bayley, Nicholas A., Fernandez, Elizabeth G., Salinas, Jennifer J., Tse, Christopher, Zhu, Henan, Su, Baolong, Plawat, Rhea, Jones, Anthony, Sammarco, Alessandro, Liau, Linda M., Graeber, Thomas G., Williams, Kevin J., Cloughesy, Timothy F., Dixon, Scott J., Bensinger, Steven J., Nathanson, David A.
Published in Cancer cell (12.06.2023)
Published in Cancer cell (12.06.2023)
Get full text
Journal Article
Temporal evolution reveals bifurcated lineages in aggressive neuroendocrine small cell prostate cancer trans-differentiation
Chen, Chia-Chun, Tran, Wendy, Song, Kai, Sugimoto, Tyler, Obusan, Matthew B, Wang, Liang, Sheu, Katherine M, Cheng, Donghui, Ta, Lisa, Varuzhanyan, Grigor, Huang, Arthur, Xu, Runzhe, Zeng, Yuanhong, Borujerdpur, Amirreza, Bayley, Nicholas A, Noguchi, Miyako, Mao, Zhiyuan, Morrissey, Colm, Corey, Eva, Nelson, Peter S, Zhao, Yue, Huang, Jiaoti, Park, Jung Wook, Witte, Owen N, Graeber, Thomas G
Published in Cancer cell (11.12.2023)
Published in Cancer cell (11.12.2023)
Get full text
Journal Article
Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma
Mai, Wilson X, Gosa, Laura, Daniels, Veerle W, Ta, Lisa, Tsang, Jonathan E, Higgins, Brian, Gilmore, W Blake, Bayley, Nicholas A, Harati, Mitra Dehghan, Lee, Jason T, Yong, William H, Kornblum, Harley I, Bensinger, Steven J, Mischel, Paul S, Rao, P Nagesh, Clark, Peter M, Cloughesy, Timothy F, Letai, Anthony, Nathanson, David A
Published in Nature medicine (01.11.2017)
Published in Nature medicine (01.11.2017)
Get full text
Journal Article
An HK2 Antisense Oligonucleotide Induces Synthetic Lethality in HK1 - HK2 + Multiple Myeloma
Xu, Shili, Zhou, Tianyuan, Doh, Hanna M, Trinh, K Ryan, Catapang, Art, Lee, Jason T, Braas, Daniel, Bayley, Nicholas A, Yamada, Reiko E, Vasuthasawat, Alex, Sasine, Joshua P, Timmerman, John M, Larson, Sarah M, Kim, Youngsoo, MacLeod, A Robert, Morrison, Sherie L, Herschman, Harvey R
Published in Cancer research (Chicago, Ill.) (15.05.2019)
Published in Cancer research (Chicago, Ill.) (15.05.2019)
Get full text
Journal Article
Hexokinase 2 is targetable for HK1 negative, HK2 positive tumors from a wide variety of tissues of origin
Xu, Shili, Catapang, Arthur, Doh, Hanna M, Bayley, Nicholas A, Lee, Jason T, Braas, Daniel, Graeber, Thomas G, Herschman, Harvey R
Published in The Journal of nuclear medicine (1978) (01.02.2019)
Published in The Journal of nuclear medicine (1978) (01.02.2019)
Get full text
Journal Article
Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma
Hu, Junhui, Tan, Ping, Ishihara, Moe, Bayley, Nicholas A., Schokrpur, Shiruyeh, Reynoso, Jeremy G., Zhang, Yangjun, Lim, Raymond J., Dumitras, Camelia, Yang, Lu, Dubinett, Steven M., Jat, Parmjit S., Van Snick, Jacques, Huang, Jiaoti, Chin, Arnold I., Prins, Robert M., Graeber, Thomas G., Xu, Hua, Wu, Lily
Published in Signal transduction and targeted therapy (17.04.2023)
Published in Signal transduction and targeted therapy (17.04.2023)
Get full text
Journal Article
Hexokinase 2 Is Targetable for HK1-Negative, HK2-Positive Tumors from a Wide Variety of Tissues of Origin
Xu, Shili, Catapang, Arthur, Doh, Hanna M., Bayley, Nicholas A., Lee, Jason T., Braas, Daniel, Graeber, Thomas G., Herschman, Harvey R.
Published in Journal of Nuclear Medicine (01.02.2019)
Published in Journal of Nuclear Medicine (01.02.2019)
Get full text
Journal Article
Glioblastoma Neurovascular Progenitor Orchestrates Tumor Cell Type Diversity
Fazzari, Elisa, Azizad, Daria J, Yu, Kwanha, Ge, Weihong, Li, Matthew X, Nano, Patricia R, Kan, Ryan L, Tum, Hong A, Tse, Christopher, Bayley, Nicholas A, Haka, Vjola, Cadet, Dimitri, Perryman, Travis, Soto, Jose A, Wick, Brittney, Raleigh, David R, Crouch, Elizabeth E, Patel, Kunal S, Liau, Linda M, Deneen, Benjamin, Nathanson, David A, Bhaduri, Aparna
Published in bioRxiv (24.07.2024)
Published in bioRxiv (24.07.2024)
Get full text
Journal Article
IMMU-12. ABERRANT EGFR SIGNALING IS ASSOCIATED WITH DIMINISHED CYTOTOXIC T-CELL INFILTRATION IN GLIOBLASTOMA PATIENTS
Pioso, Marissa, Sun, Lu, Bayley, Nicholas, Anil, Amanda, Lee, Alexander, Nathanson, David, Prins, Robert
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Get full text
Journal Article
CSIG-15. PTN-PTPRZ1 SIGNALING MEDIATES TUMOR-NORMAL CROSSTALK IN GLIOBLASTOMA
Kan, Ryan, Ge, Weihong, Yilgor, Can, Bayley, Nicholas, Tse, Christopher, Tum, Andrew, Patel, Kunal, Nathanson, David, Bhaduri, Aparna
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Get full text
Journal Article
DIPG-55. DIRECT BRAIN-TO-BRAIN WORKFLOW ENABLES THE PRECLINICAL MODELING OF PEDIATRIC GLIOMAS
Tum, Hong, Tse, Christopher, Salinas, Jennifer, Bayley, Nicholas, Zhu, Henan, Cloughesy, Timothy, Liau, Linda, Graeber, Thomas, Nathanson, David
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Get full text
Journal Article
DIPG-56. PEDIATRIC GLIOMAS EXHIBIT A UNIQUE LIPID METABOLIC PHENOTYPE DISTINCT FROM ADULT GBMS
Salinas, Jennifer, Minami, Jenna, Bayley, Nicholas, Tse, Christopher, Zhu, Henan, Tum, Hong, Cloughesy, Timothy, Liau, Linda, Graber, Thomas, Nathanson, David
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Get full text
Journal Article
CBIO-27. INTEGRATED FUNCTIONAL AND MOLECULAR CHARACTERIZATION OF THE INTRINSIC APOPTOTIC MACHINERY IDENTIFIES THERAPEUTIC VULNERABILITIES IN GLIOBLASTOMA
Fernandez, Elizabeth, Mia, Wilson, Bayley, Nicholas, Zhu, Henan, Tse, Christopher, Liau, Linda, Cloughesy, Timothy, Nathanson, David
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Get full text
Journal Article
STEM-11. A GLIOBLASTOMA SINGLE-CELL META-ATLAS IDENTIFIES NOVEL NEUROVASCULAR PROGENITOR IN TUMORS
Fazzari, Elisa, Azizad, Daria, Li, Matthew, Ge, Weihong, Bayley, Nicholas, Tse, Christopher, Tum, Andrew, Raleigh, David, Patel, Kunal, Crouch, Elizabeth, Nathanson, David, Bhaduri, Aparna
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Get full text
Journal Article
CBIO-25. INTEGRATED MOLECULAR AND BH3 PROFILING OF THE INTRINSIC APOPTOTIC MACHINERY IDENTIFIES THERAPEUTIC VULNERABILITIES IN GLIOBLASTOMA
Fernandez, Elizabeth, Mai, Wilson, Bayley, Nicholas, Tse, Christopher, Liau, Linda, Cloughesy, Timothy, Letai, Anthony, Nathanson, David
Published in Neuro-oncology (Charlottesville, Va.) (09.11.2020)
Published in Neuro-oncology (Charlottesville, Va.) (09.11.2020)
Get full text
Journal Article
CBIO-05. LIPID METABOLIC REPROGRAMMING SENSITIZES A MOLECULARLY-DEFINED SUBSET OF GLIOBLASTOMAS TO FERROPTOSIS
Morrow, Danielle, Nathanson, David, Cloughesy, Timothy, Prins, Robert, Bayley, Nicholas, Liau, Linda, Bensinger, Steven, Williams, Kevin
Published in Neuro-oncology (Charlottesville, Va.) (09.11.2020)
Published in Neuro-oncology (Charlottesville, Va.) (09.11.2020)
Get full text
Journal Article
CBIO-03. A COMPREHENSIVE CHARACTERIZATION OF THE GBM LIPIDOME REVEALS A MOLECULARLY-DEFINED SUB-GROUP WITH HEIGHTENED SENSITIVITY TO FERROPTOSIS
Morrow, Danielle, Minami, Jenna, Bayley, Nicholas, Williams, Kevin, Prins, Robert, Liau, Linda, Cloughesy, Timothy, Bensinger, Steven, Nathanson, David
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Get full text
Journal Article
TAMI-26. INVESTIGATING TUMOR MICROENVIRONMENT METABOLIC DEPENDENCIES IN GLIOBLASTOMA
Minami, Jenna, Bayley, Nicholas, Tse, Christopher, Morrow, Danielle, Zhu, Henan, Yong, William, Liau, Linda, Cloughesy, Timothy, Graeber, Thomas, Nathanson, David
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Get full text
Journal Article