New approaches for the treatment of Alzheimer’s disease
Fish, Paul V., Steadman, David, Bayle, Elliott D., Whiting, Paul
Published in Bioorganic & medicinal chemistry letters (15.01.2019)
Published in Bioorganic & medicinal chemistry letters (15.01.2019)
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Journal Article
Systematic Investigation of the Permeability of Androgen Receptor PROTACs
Scott, Duncan E, Rooney, Timothy P. C, Bayle, Elliott D, Mirza, Tashfina, Willems, Henriette M. G, Clarke, Jonathan H, Andrews, Stephen P, Skidmore, John
Published in ACS medicinal chemistry letters (13.08.2020)
Published in ACS medicinal chemistry letters (13.08.2020)
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Journal Article
Design of a Chemical Probe for the Bromodomain and Plant Homeodomain Finger-Containing (BRPF) Family of Proteins
Igoe, Niall, Bayle, Elliott D, Tallant, Cynthia, Fedorov, Oleg, Meier, Julia C, Savitsky, Pavel, Rogers, Catherine, Morias, Yannick, Scholze, Sarah, Boyd, Helen, Cunoosamy, Danen, Andrews, David M, Cheasty, Anne, Brennan, Paul E, Müller, Susanne, Knapp, Stefan, Fish, Paul V
Published in Journal of medicinal chemistry (24.08.2017)
Published in Journal of medicinal chemistry (24.08.2017)
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Journal Article
An improved, scalable synthesis of Notum inhibitor LP-922056 using 1-chloro-1,2-benziodoxol-3-one as a superior electrophilic chlorinating agent
Willis, Nicky J, Bayle, Elliott D, Papageorgiou, George, Steadman, David, Atkinson, Benjamin N, Mahy, William, Fish, Paul V
Published in Beilstein journal of organic chemistry (19.11.2019)
Published in Beilstein journal of organic chemistry (19.11.2019)
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Journal Article
Cortical dynamics of externally and self-directed attention: a MEG study of a card sorting task
Fonlupt, P., Henaff, M.A., Bayle, D., Krolak-Salmon, P.
Published in NeuroImage (Orlando, Fla.) (01.07.2009)
Published in NeuroImage (Orlando, Fla.) (01.07.2009)
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Journal Article
Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling
Bayle, Elliott D, Svensson, Fredrik, Atkinson, Benjamin N, Steadman, David, Willis, Nicky J, Woodward, Hannah L, Whiting, Paul, Vincent, Jean-Paul, Fish, Paul V
Published in Journal of medicinal chemistry (22.04.2021)
Published in Journal of medicinal chemistry (22.04.2021)
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Journal Article
New small molecule inhibitors of histone methyl transferase DOT1L with a nitrile as a non-traditional replacement for heavy halogen atoms
Spurr, Sophie S., Bayle, Elliott D., Yu, Wenyu, Li, Fengling, Tempel, Wolfram, Vedadi, Masoud, Schapira, Matthieu, Fish, Paul V.
Published in Bioorganic & medicinal chemistry letters (15.09.2016)
Published in Bioorganic & medicinal chemistry letters (15.09.2016)
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Journal Article
Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit
Willis, Nicky J., Mahy, William, Sipthorp, James, Zhao, Yuguang, Woodward, Hannah L., Atkinson, Benjamin N., Bayle, Elliott D., Svensson, Fredrik, Frew, Sarah, Jeganathan, Fiona, Monaghan, Amy, Benvegnù, Stefano, Jolly, Sarah, Vecchia, Luca, Ruza, Reinis R., Kjær, Svend, Howell, Steven, Snijders, Ambrosius P., Bictash, Magda, Salinas, Patricia C., Vincent, Jean-Paul, Jones, E. Yvonne, Whiting, Paul, Fish, Paul V.
Published in Journal of medicinal chemistry (26.05.2022)
Published in Journal of medicinal chemistry (26.05.2022)
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Journal Article
Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitors
Atkinson, Benjamin N., Steadman, David, Mahy, William, Zhao, Yuguang, Sipthorp, James, Bayle, Elliott D., Svensson, Fredrik, Papageorgiou, George, Jeganathan, Fiona, Frew, Sarah, Monaghan, Amy, Bictash, Magda, Jones, E. Yvonne, Fish, Paul V.
Published in Bioorganic & medicinal chemistry letters (01.02.2020)
Published in Bioorganic & medicinal chemistry letters (01.02.2020)
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Journal Article
Design of a Biased Potent Small Molecule Inhibitor of the Bromodomain and PHD Finger-Containing (BRPF) Proteins Suitable for Cellular and in Vivo Studies
Igoe, Niall, Bayle, Elliott D, Fedorov, Oleg, Tallant, Cynthia, Savitsky, Pavel, Rogers, Catherine, Owen, Dafydd R, Deb, Gauri, Somervaille, Tim C. P, Andrews, David M, Jones, Neil, Cheasty, Anne, Ryder, Hamish, Brennan, Paul E, Müller, Susanne, Knapp, Stefan, Fish, Paul V
Published in Journal of medicinal chemistry (26.01.2017)
Published in Journal of medicinal chemistry (26.01.2017)
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Journal Article
Physical exercise influences attentional orientation towards emotional stimuli
Mansouri, N., Coutté, A., Dru, V., Bayle, D.
Published in International journal of psychophysiology (01.06.2023)
Published in International journal of psychophysiology (01.06.2023)
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Journal Article
Structural Analysis and Development of Notum Fragment Screening Hits
Zhao, Yuguang, Mahy, William, Willis, Nicky J, Woodward, Hannah L, Steadman, David, Bayle, Elliott D, Atkinson, Benjamin N, Sipthorp, James, Vecchia, Luca, Ruza, Reinis R, Harlos, Karl, Jeganathan, Fiona, Constantinou, Stefan, Costa, Artur, Kjær, Svend, Bictash, Magda, Salinas, Patricia C, Whiting, Paul, Vincent, Jean-Paul, Fish, Paul V, Jones, E Yvonne
Published in ACS chemical neuroscience (06.07.2022)
Published in ACS chemical neuroscience (06.07.2022)
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Journal Article
Selective Targeting of Bromodomains of the Bromodomain-PHD Fingers Family Impairs Osteoclast Differentiation
Meier, Julia C, Tallant, Cynthia, Fedorov, Oleg, Witwicka, Hanna, Hwang, Sung-Yong, van Stiphout, Ruud G, Lambert, Jean-Philippe, Rogers, Catherine, Yapp, Clarence, Gerstenberger, Brian S, Fedele, Vita, Savitsky, Pavel, Heidenreich, David, Daniels, Danette L, Owen, Dafydd R, Fish, Paul V, Igoe, Niall M, Bayle, Elliott D, Haendler, Bernard, Oppermann, Udo C.T, Buffa, Francesca, Brennan, Paul E, Müller, Susanne, Gingras, Anne Claude, Odgren, Paul R, Birnbaum, Mark J, Knapp, Stefan
Published in ACS chemical biology (20.10.2017)
Published in ACS chemical biology (20.10.2017)
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Journal Article
Changes in gene expression in the lungs of Mg-deficient mice are related to an inflammatory process
NASULEWICZ, A, ZIMOWSKA, W, BAYLE, D, DZIMIRA, S, MADEJ, J, RAYSSIGUIER, Y, OPOLSKI, A, MAZUR, A
Published in Magnesium research (01.12.2004)
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Published in Magnesium research (01.12.2004)
Journal Article
Effects of ionizing radiation (neutrons/gamma rays) on plasma lipids and lipoproteins in rats
Feurgard, C, Bayle, D, Guézingar, F, Sérougne, C, Mazur, A, Lutton, C, Aigueperse, J, Gourmelon, P, Mathé, D
Published in Radiation research (01.07.1998)
Published in Radiation research (01.07.1998)
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Journal Article
Response of diamine oxidase and other plasma copper biomarkers to various dietary copper intakes in the rat and evaluation of copper absorption with a stable isotope
Feillet-Coudray, C., Coudray, C., Bayle, D., Rock, E., Rayssiguier, Y., Mazur, A.
Published in British journal of nutrition (01.05.2000)
Published in British journal of nutrition (01.05.2000)
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Journal Article