AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity
Blair, Jessica M. A., Bavro, Vassiliy N., Ricci, Vito, Modi, Niraj, Cacciotto, Pierpaolo, Kleinekathӧfer, Ulrich, Ruggerone, Paolo, Vargiu, Attilio V., Baylay, Alison J., Smith, Helen E., Brandon, Yvonne, Galloway, David, Piddock, Laura J. V.
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2015)
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Identification of binding residues between periplasmic adapter protein (PAP) and RND efflux pumps explains PAP-pump promiscuity and roles in antimicrobial resistance
McNeil, Helen E, Alav, Ilyas, Torres, Ricardo Corona, Rossiter, Amanda E, Laycock, Eve, Legood, Simon, Kaur, Inderpreet, Davies, Matthew, Wand, Matthew, Webber, Mark A, Bavro, Vassiliy N, Blair, Jessica M A
Published in PLoS pathogens (01.12.2019)
Published in PLoS pathogens (01.12.2019)
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Structural and Functional Analysis of the Escherichia coli Acid-Sensing Histidine Kinase EvgS
Sen, Hrishiraj, Aggarwal, Nikhil, Ishionwu, Chibueze, Hussain, Nosheen, Parmar, Chandni, Jamshad, Mohammed, Bavro, Vassiliy N, Lund, Peter A
Published in Journal of bacteriology (15.09.2017)
Published in Journal of bacteriology (15.09.2017)
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Journal Article
Structure of a KirBac potassium channel with an open bundle crossing indicates a mechanism of channel gating
Bavro, Vassiliy N, De Zorzi, Rita, Schmidt, Matthias R, Muniz, João R C, Zubcevic, Lejla, Sansom, Mark S P, Vénien-Bryan, Catherine, Tucker, Stephen J
Published in Nature structural & molecular biology (01.02.2012)
Published in Nature structural & molecular biology (01.02.2012)
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Journal Article
The role of ABC transporter DrrABC in the export of PDIM in Mycobacterium tuberculosis
Moolla, Nabiela, Weaver, Helen, Bailo, Rebeca, Singh, Albel, Bavro, Vassiliy N., Bhatt, Apoorva
Published in Cell surface (Amsterdam) (01.12.2024)
Published in Cell surface (Amsterdam) (01.12.2024)
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Journal Article
Mass spectrometry of membrane transporters reveals subunit stoichiometry and interactions
Bavro, Vassiliy N, Miguel, Ricardo Núñez, Schaedler, Theresia A, Robinson, Carol V, Zhou, Min, Barrera, Nelson P, van Veen, Hendrik W, Venter, Henrietta, Seeger, Markus A, Tate, Christopher G, Isaacson, Shoshanna C, Walmsley, Adrian R, Welch, Alex, Korkhov, Vladimir M
Published in Nature methods (01.08.2009)
Published in Nature methods (01.08.2009)
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Cefotaxime Exposure Selects Mutations within the CA-Domain of envZ Which Promote Antibiotic Resistance but Repress Biofilm Formation in Salmonella
Trampari, Eleftheria, Zhang, Chuanzhen, Gotts, Kathryn, Savva, George M, Bavro, Vassiliy N, Webber, Mark
Published in Microbiology spectrum (01.06.2022)
Published in Microbiology spectrum (01.06.2022)
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Journal Article
ATP-Binding Cassette Transporter VcaM from Vibrio cholerae is Dependent on the Outer Membrane Factor Family for Its Function
Lu, Wen-Jung, Lin, Hsuan-Ju, Janganan, Thamarai K, Li, Cheng-Yi, Chin, Wei-Chiang, Bavro, Vassiliy N, Lin, Hong-Ting Victor
Published in International journal of molecular sciences (27.03.2018)
Published in International journal of molecular sciences (27.03.2018)
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Journal Article
Structure-function analysis of MmpL7-mediated lipid transport in mycobacteria
Moolla, Nabiela, Bailo, Rebeca, Marshall, Robert, Bavro, Vassiliy N., Bhatt, Apoorva
Published in Cell surface (Amsterdam) (01.12.2021)
Published in Cell surface (Amsterdam) (01.12.2021)
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Journal Article
Quantitative real-time analysis of the efflux by the MacAB-TolC tripartite efflux pump clarifies the role of ATP hydrolysis within mechanotransmission mechanism
Souabni, Hager, Batista dos Santos, William, Cece, Quentin, Catoire, Laurent J., Puvanendran, Dhenesh, Bavro, Vassiliy N., Picard, Martin
Published in Communications biology (22.04.2021)
Published in Communications biology (22.04.2021)
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Journal Article
MacB ABC Transporter Is a Dimer Whose ATPase Activity and Macrolide-binding Capacity Are Regulated by the Membrane Fusion Protein MacA
Lin, Hong Ting, Bavro, Vassiliy N., Barrera, Nelson P., Frankish, Helen M., Velamakanni, Saroj, van Veen, Hendrik W., Robinson, Carol V., Borges-Walmsley, M. Inês, Walmsley, Adrian R.
Published in The Journal of biological chemistry (09.01.2009)
Published in The Journal of biological chemistry (09.01.2009)
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Mutational and topological analysis of the Escherichia coli BamA protein
Browning, Douglas F, Matthews, Sophie A, Rossiter, Amanda E, Sevastsyanovich, Yanina R, Jeeves, Mark, Mason, Jessica L, Wells, Timothy J, Wardius, Catherine A, Knowles, Timothy J, Cunningham, Adam F, Bavro, Vassiliy N, Overduin, Michael, Henderson, Ian R
Published in PloS one (23.12.2013)
Published in PloS one (23.12.2013)
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Editorial: Bacterial Mechanisms of Antibiotic Resistance: A Structural Perspective
Conn, Graeme L, Bavro, Vassiliy N, Davies, Christopher
Published in Frontiers in molecular biosciences (14.08.2019)
Published in Frontiers in molecular biosciences (14.08.2019)
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Journal Article
Cryo-EM Structure and Molecular Dynamics Analysis of the Fluoroquinolone Resistant Mutant of the AcrB Transporter from Salmonella
Johnson, Rachel M, Fais, Chiara, Parmar, Mayuriben, Cheruvara, Harish, Marshall, Robert L, Hesketh, Sophie J, Feasey, Matthew C, Ruggerone, Paolo, Vargiu, Attilio V, Postis, Vincent L G, Muench, Stephen P, Bavro, Vassiliy N
Published in Microorganisms (Basel) (23.06.2020)
Published in Microorganisms (Basel) (23.06.2020)
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Journal Article
Control of KirBac3.1 Potassium Channel Gating at the Interface between Cytoplasmic Domains
Zubcevic, Lejla, Bavro, Vassiliy N., Muniz, Joao R.C., Schmidt, Matthias R., Wang, Shizhen, De Zorzi, Rita, Venien-Bryan, Catherine, Sansom, Mark S.P., Nichols, Colin G., Tucker, Stephen J.
Published in The Journal of biological chemistry (03.01.2014)
Published in The Journal of biological chemistry (03.01.2014)
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