Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420
Blondiaux, Nicolas, Moune, Martin, Desroses, Matthieu, Frita, Rosangela, Flipo, Marion, Mathys, Vanessa, Soetaert, Karine, Kiass, Mehdi, Delorme, Vincent, Djaout, Kamel, Trebosc, Vincent, Kemmer, Christian, Wintjens, René, Wohlkönig, Alexandre, Antoine, Rudy, Huot, Ludovic, Hot, David, Coscolla, Mireia, Feldmann, Julia, Gagneux, Sebastien, Locht, Camille, Brodin, Priscille, Gitzinger, Marc, Déprez, Benoit, Willand, Nicolas, Baulard, Alain R.
Published in Science (American Association for the Advancement of Science) (17.03.2017)
Published in Science (American Association for the Advancement of Science) (17.03.2017)
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Direct Measurement of Hydrophobic Forces on Cell Surfaces Using AFM
Alsteens, David, Dague, Etienne, Rouxhet, Paul G, Baulard, Alain R, Dufrêne, Yves F
Published in Langmuir (20.11.2007)
Published in Langmuir (20.11.2007)
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Exploring the Antitubercular Activity of Anthranilic Acid Derivatives: From MabA (FabG1) Inhibition to Intrabacterial Acidification
Faïon, Léo, Djaout, Kamel, Pintiala, Catalin, Piveteau, Catherine, Leroux, Florence, Biela, Alexandre, Slupek, Stéphanie, Antoine, Rudy, Záhorszká, Monika, Cantrelle, Francois-Xavier, Hanoulle, Xavier, Korduláková, Jana, Deprez, Benoit, Willand, Nicolas, Baulard, Alain R, Flipo, Marion
Published in Pharmaceuticals (Basel, Switzerland) (22.02.2023)
Published in Pharmaceuticals (Basel, Switzerland) (22.02.2023)
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Organization of the mycobacterial cell wall: a nanoscale view
Alsteens, David, Verbelen, Claire, Dague, Etienne, Raze, Dominique, Baulard, Alain R., Dufrêne, Yves F.
Published in Pflügers Archiv (01.04.2008)
Published in Pflügers Archiv (01.04.2008)
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EthR, a repressor of the TetR/CamR family implicated in ethionamide resistance in mycobacteria, octamerizes cooperatively on its operator
Engohang‐Ndong, Jean, Baillat, David, Aumercier, Marc, Bellefontaine, Flore, Besra, Gurdyal S., Locht, Camille, Baulard, Alain R.
Published in Molecular microbiology (01.01.2004)
Published in Molecular microbiology (01.01.2004)
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Unique Mechanism of Action of the Thiourea Drug Isoxyl on Mycobacterium tuberculosis
Phetsuksiri, Benjawan, Jackson, Mary, Scherman, Hataichanok, McNeil, Michael, Besra, Gurdyal S., Baulard, Alain R., Slayden, Richard A., DeBarber, Andrea E., Barry, Clifton E., Baird, Mark S., Crick, Dean C., Brennan, Patrick J.
Published in The Journal of biological chemistry (26.12.2003)
Published in The Journal of biological chemistry (26.12.2003)
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Activation of the Pro-drug Ethionamide Is Regulated in Mycobacteria
Baulard, A R, Betts, J C, Engohang-Ndong, J, Quan, S, McAdam, R A, Brennan, P J, Locht, C, Besra, G S
Published in The Journal of biological chemistry (08.09.2000)
Published in The Journal of biological chemistry (08.09.2000)
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Structural analysis of the interaction between spiroisoxazoline SMARt-420 and the Mycobacterium tuberculosis repressor EthR2
Wohlkönig, Alexandre, Remaut, Han, Moune, Martin, Tanina, Abdalkarim, Meyer, Franck, Desroses, Matthieu, Steyaert, Jan, Willand, Nicolas, Baulard, Alain R., Wintjens, René
Published in Biochemical and biophysical research communications (27.05.2017)
Published in Biochemical and biophysical research communications (27.05.2017)
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Antimycobacterial Activities of Isoxyl and New Derivatives through the Inhibition of Mycolic Acid Synthesis
PHETSUKSIRI, B, BAULARD, A. R, COOPER, A. M, MINNIKIN, D. E, DOUGLAS, J. D, BESRA, G. S, BRENNAN, P. J
Published in Antimicrobial Agents and Chemotherapy (01.05.1999)
Published in Antimicrobial Agents and Chemotherapy (01.05.1999)
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Ppm1, a novel polyprenol monophosphomannose synthase from Mycobacterium tuberculosis
Gurcha, Sudagar S, Baulard, Alain R, Kremer, Laurent, Locht, Camille, Moody, D Branch, Muhlecker, Walter, Costello, Catherine E, Crick, Dean C, Brennan, Patrick J, Besra, Gurdyal S
Published in Biochemical journal (15.07.2002)
Published in Biochemical journal (15.07.2002)
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Crystal structure of the Mycobacterium tuberculosis VirS regulator reveals its interaction with the lead compound SMARt751
Grosse, Camille, Sigoillot, Maud, Megalizzi, Véronique, Tanina, Abdalkarim, Willand, Nicolas, Baulard, Alain R., Wintjens, René
Published in Journal of structural biology (01.06.2024)
Published in Journal of structural biology (01.06.2024)
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Tuberculosis: The drug development pipeline at a glance
Villemagne, Baptiste, Crauste, Céline, Flipo, Marion, Baulard, Alain R., Déprez, Benoit, Willand, Nicolas
Published in European journal of medicinal chemistry (01.05.2012)
Published in European journal of medicinal chemistry (01.05.2012)
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Molecular Mapping of Lipoarabinomannans on Mycobacteria
Verbelen, Claire, Christiaens, Nicolas, Alsteens, David, Dupres, Vincent, Baulard, Alain R, Dufrêne, Yves F
Published in Langmuir (21.04.2009)
Published in Langmuir (21.04.2009)
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Thiolactomycin and related analogues as novel anti-mycobacterial agents targeting KasA and KasB condensing enzymes in Mycobacterium tuberculosis
Kremer, L, Douglas, J D, Baulard, A R, Morehouse, C, Guy, M R, Alland, D, Dover, L G, Lakey, J H, Jacobs, Jr, W R, Brennan, P J, Minnikin, D E, Besra, G S
Published in The Journal of biological chemistry (02.06.2000)
Published in The Journal of biological chemistry (02.06.2000)
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Cyclodextrin-based nanocarriers containing a synergic drug combination: A potential formulation for pulmonary administration of antitubercular drugs
Salzano, Giuseppina, Wankar, Jitendra, Ottani, Stefano, Villemagne, Baptiste, Baulard, Alain R., Willand, Nicolas, Brodin, Priscille, Manet, Ilse, Gref, Ruxandra
Published in International journal of pharmaceutics (15.10.2017)
Published in International journal of pharmaceutics (15.10.2017)
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In Vivo Interaction between the Polyprenol Phosphate Mannose Synthase Ppm1 and the Integral Membrane Protein Ppm2 from Mycobacterium smegmatis Revealed by a Bacterial Two-hybrid System
Baulard, A R, Gurcha, S S, Engohang-Ndong, J, Gouffi, K, Locht, C, Besra, G S
Published in The Journal of biological chemistry (24.01.2003)
Published in The Journal of biological chemistry (24.01.2003)
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Intrinsic Antibacterial Activity of Nanoparticles Made of β‑Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis
Machelart, Arnaud, Salzano, Giuseppina, Li, Xue, Demars, Aurore, Debrie, Anne-Sophie, Menendez-Miranda, Mario, Pancani, Elisabetta, Jouny, Samuel, Hoffmann, Eik, Deboosere, Nathalie, Belhaouane, Imène, Rouanet, Carine, Simar, Sophie, Talahari, Smaïl, Giannini, Valerie, Villemagne, Baptiste, Flipo, Marion, Brosch, Roland, Nesslany, Fabrice, Deprez, Benoit, Muraille, Eric, Locht, Camille, Baulard, Alain R, Willand, Nicolas, Majlessi, Laleh, Gref, Ruxandra, Brodin, Priscille
Published in ACS nano (23.04.2019)
Published in ACS nano (23.04.2019)
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Loss-of-function mutations in ndh do not confer delamanid, ethionamide, isoniazid, or pretomanid resistance in Mycobacterium tuberculosis
Pandey, Sushil, Vilchèze, Catherine, Werngren, Jim, Bainomugisa, Arnold, Mansjö, Mikael, Groenheit, Ramona, Miotto, Paolo, Cirillo, Daniela M, Coulter, Christopher, Baulard, Alain R, Schön, Thomas, Jacobs, Jr, William R, Djaout, Kamel, Köser, Claudio U
Published in Antimicrobial agents and chemotherapy (10.01.2024)
Published in Antimicrobial agents and chemotherapy (10.01.2024)
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Efficient analoging around ethionamide to explore thioamides bioactivation pathways triggered by boosters in Mycobacterium tuberculosis
Prieri, Marion, Frita, Rosangela, Probst, Nicolas, Sournia-Saquet, Alix, Bourotte, Marilyne, Déprez, Benoit, Baulard, Alain R., Willand, Nicolas
Published in European journal of medicinal chemistry (05.11.2018)
Published in European journal of medicinal chemistry (05.11.2018)
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