Loss of hepatic PPARα in mice causes hypertension and cardiovascular disease
Badmus, Olufunto O, Kipp, Zachary A, Bates, Evelyn A, da Silva, Alexandre A, Taylor, Lucy C, Martinez, Genesee J, Lee, Wang-Hsin, Creeden, Justin F, Hinds, Jr, Terry D, Stec, David E
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.07.2023)
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.07.2023)
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Journal Article
FOXS1 is increased in liver fibrosis and regulates TGFβ responsiveness and proliferation pathways in human hepatic stellate cells
Bates, Evelyn A., Kipp, Zachary A., Lee, Wang-Hsin, Martinez, Genesee J., Weaver, Lauren, Becker, Kathryn N., Pauss, Sally N., Creeden, Justin F., Anspach, Garrett B., Helsley, Robert N., Xu, Mei, Bruno, Maria E.C., Starr, Marlene E., Hinds, Terry D.
Published in The Journal of biological chemistry (01.03.2024)
Published in The Journal of biological chemistry (01.03.2024)
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Journal Article
Glucocorticoid resistance remodels liver lipids and prompts lipogenesis, eicosanoid, and inflammatory pathways
Martinez, Genesee J., Kipp, Zachary A., Lee, Wang-Hsin, Bates, Evelyn A., Morris, Andrew J., Marino, Joseph S., Hinds, Terry D.
Published in Prostaglandins & other lipid mediators (01.08.2024)
Published in Prostaglandins & other lipid mediators (01.08.2024)
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Journal Article
Bilirubin Levels Are Negatively Correlated with Adiposity in Obese Men and Women, and Its Catabolized Product, Urobilin, Is Positively Associated with Insulin Resistance
Kipp, Zachary A, Xu, Mei, Bates, Evelyn A, Lee, Wang-Hsin, Kern, Philip A, Hinds, Jr, Terry D
Published in Antioxidants (11.01.2023)
Published in Antioxidants (11.01.2023)
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Journal Article
Suppressing Hepatic UGT1A1 Increases Plasma Bilirubin, Lowers Plasma Urobilin, Reorganizes Kinase Signaling Pathways and Lipid Species and Improves Fatty Liver Disease
Bates, Evelyn A, Kipp, Zachary A, Martinez, Genesee J, Badmus, Olufunto O, Soundarapandian, Mangala M, Foster, Donald, Xu, Mei, Creeden, Justin F, Greer, Jennifer R, Morris, Andrew J, Stec, David E, Hinds, Jr, Terry D
Published in Biomolecules (Basel, Switzerland) (29.01.2023)
Published in Biomolecules (Basel, Switzerland) (29.01.2023)
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Journal Article
Loss of Carnitine Palmitoyltransferase 1a Reduces Docosahexaenoic Acid-Containing Phospholipids and Drives Sexually Dimorphic Liver Disease in Mice
Zelows, Mikala M., Cady, Corissa, Dharanipragada, Nikitha, Mead, Anna E., Kipp, Zachary A., Bates, Evelyn A., Varadharajan, Venkateshwari, Banerjee, Rakhee, Park, Se-Hyung, Shelman, Nathan R., Clarke, Harrison A., Hawkinson, Tara R., Medina, Terrymar, Sun, Ramon C., Lydic, Todd A., Hinds, Terry D., Brown, J. Mark, Softic, Samir, Graf, Gregory A., Helsley, Robert N.
Published in Molecular metabolism (Germany) (01.12.2023)
Published in Molecular metabolism (Germany) (01.12.2023)
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Journal Article
Bilirubin Nanoparticle Treatment in Obese Mice Inhibits Hepatic Ceramide Production and Remodels Liver Fat Content
Kipp, Zachary A, Martinez, Genesee J, Bates, Evelyn A, Maharramov, Agil B, Flight, Robert M, Moseley, Hunter N B, Morris, Andrew J, Stec, David E, Hinds, Jr, Terry D
Published in Metabolites (01.02.2023)
Published in Metabolites (01.02.2023)
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Journal Article
Knockdown of Ketohexokinase Versus Inhibition of Its Kinase Activity Exert Divergent Effects on Fructose Metabolism
Park, Se-Hyung, Fadhul, Taghreed, Conroy, Lindsey R, Clarke, Harrison A, Sun, Ramon C, Wallenius, Kristina, Boucher, Jeremie, O'Mahony, Gavin, Boianelli, Alessandro, Persson, Marie, Jung, Sunhee, Jang, Cholsoon, Loria, Analia S, Martinez, Genesee J, Kipp, Zachary A, Bates, Evelyn A, Hinds, Jr, Terry D, Divanovic, Senad, Softic, Samir
Published in JCI insight (17.10.2024)
Published in JCI insight (17.10.2024)
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Journal Article
Abstract 1514 FK506-Binding Protein 51 (FKBP51), a New Regulator of Insulin Receptor Alternative Splicing and PPARα Activation That May Control Metabolic Disorder Developments
Lee, Wang-Hsin, Bates, Evelyn, Maharramov, Agil, Martinez, Genesee, Kipp, Zachary, Xu, Mei, Hinds, Terry
Published in The Journal of biological chemistry (01.03.2024)
Published in The Journal of biological chemistry (01.03.2024)
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Journal Article
Abstract 1506 The Glucocorticoid Receptor β (GRβ) induces glucocorticoid resistance and PPARγ activation to increase eicosanoid and monoacylglyceride synthesis which leads to hepatic lipid accumulation
Martinez, Genesee, Kipp, Zachary, Lee, Wang-Hsin, Bates, Evelyn, Stec, David, Hinds, Terry
Published in The Journal of biological chemistry (01.03.2024)
Published in The Journal of biological chemistry (01.03.2024)
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Journal Article
Abstract 1520 PamGene Nuclear Hormone Receptor Analysis Reveals Dietary Influences of the PPARgamma Coregulator Interactome and Differential Signaling Mechanisms
Bates, Evelyn, Kipp, Zachary, Pauss, Sally, Lee, Wang-Hsin, Martinez, Genesee, Xu, Mei, Hinds, Terry
Published in The Journal of biological chemistry (01.03.2024)
Published in The Journal of biological chemistry (01.03.2024)
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Journal Article
Advanced PamGene Coregulator Interactome Analysis of PPARgamma Reveals that Diet Influences Regulatory Protein Interactions and Signaling Mechanisms
Bates, Evelyn, Kipp, Zachary, Pauss, Sally, Lee, Wang-Hsin, Martinez, Genesee, Xu, Mei, Hinds, Terry
Published in Physiology (Bethesda, Md.) (01.05.2024)
Published in Physiology (Bethesda, Md.) (01.05.2024)
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Journal Article
FK506-Binding Protein 51 (FKBP51) Suppresses PPARα Activity and Shifts the Insulin Receptor Alternative Splicing Driving Hepatic Insulin Resistance
Lee, Wang-Hsin, Bates, Evelyn, Maharramov, Agil, Martinez, Genesee, Kipp, Zachary, Xu, Mei, Hinds, Terry
Published in Physiology (Bethesda, Md.) (01.05.2024)
Published in Physiology (Bethesda, Md.) (01.05.2024)
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Journal Article
An Innovative Liver-Specific GalNAc-RNAi Suppression of UGT1A1 in Obese Mice Improves Metabolic-Associated Fatty Liver Disease (MAFLD)
Bates, Evelyn, Kipp, Zachary, Badmus, Olufunto, Xu, Mei, Mitchell, Zachary, Stec, David, Hinds, Jr, Terry
Published in Physiology (Bethesda, Md.) (01.05.2023)
Published in Physiology (Bethesda, Md.) (01.05.2023)
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Journal Article
The loss of hepatic PPARα prompts fatty liver disease-induced hypertension and cardiovascular disease
Badmus, Olufunto, Kipp, Zachary Kipp, Bates, Evelyn, da Silva, Alexandre, Taylor, Lucy, Martinez, Genesee, Hinds, Terry, Stec, David
Published in Physiology (Bethesda, Md.) (01.05.2023)
Published in Physiology (Bethesda, Md.) (01.05.2023)
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Journal Article