Exploiting a natural conformational switch to engineer an interleukin-2 ‘superkine’
Levin, Aron M., Bates, Darren L., Ring, Aaron M., Krieg, Carsten, Lin, Jack T., Su, Leon, Moraga, Ignacio, Raeber, Miro E., Bowman, Gregory R., Novick, Paul, Pande, Vijay S., Fathman, C. Garrison, Boyman, Onur, Garcia, K. Christopher
Published in Nature (London) (26.04.2012)
Published in Nature (London) (26.04.2012)
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Journal Article
DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation
Chen, Yongheng, Bates, Darren L., Dey, Raja, Chen, Po-Han, Machado, Ana Carolina Dantas, Laird-Offringa, Ite A., Rohs, Remo, Chen, Lin
Published in Cell reports (Cambridge) (29.11.2012)
Published in Cell reports (Cambridge) (29.11.2012)
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Journal Article
Structure of the Forkhead Domain of FOXP2 Bound to DNA
Stroud, James C., Wu, Yongqing, Bates, Darren L., Han, Aidong, Nowick, Katja, Paabo, Svante, Tong, Harry, Chen, Lin
Published in Structure (London) (2006)
Published in Structure (London) (2006)
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Journal Article
Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains
Guo, Liang, Han, Aidong, Bates, Darren L, Cao, Jue, Chen, Lin
Published in Proceedings of the National Academy of Sciences - PNAS (13.03.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (13.03.2007)
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Journal Article
Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor
Min, Xiaoshan, Yie, Junming, Wang, Jinghong, Chung, Ben C, Huang, Ching-Shin, Xu, Haoda, Yang, Jie, Deng, Liying, Lin, Joanne, Chen, Qing, Abbott, Christina M, Gundel, Caroline, Thibault, Stephen A, Meng, Tina, Bates, Darren L, Lloyd, David J, Véniant, Murielle M, Wang, Zhulun
Published in mAbs (01.01.2020)
Published in mAbs (01.01.2020)
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Journal Article
FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT
Wu, Yongqing, Borde, Madhuri, Heissmeyer, Vigo, Feuerer, Markus, Lapan, Ariya D., Stroud, James C., Bates, Darren L., Guo, Liang, Han, Aidong, Ziegler, Steven F., Mathis, Diane, Benoist, Christophe, Chen, Lin, Rao, Anjana
Published in Cell (28.07.2006)
Published in Cell (28.07.2006)
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Journal Article
Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines
Junttila, Ilkka S, Creusot, Remi J, Moraga, Ignacio, Bates, Darren L, Wong, Michael T, Alonso, Michael N, Suhoski, Megan M, Lupardus, Patrick, Meier-Schellersheim, Martin, Engleman, Edgar G, Utz, Paul J, Fathman, C Garrison, Paul, William E, Garcia, K Christopher
Published in Nature chemical biology (01.12.2012)
Published in Nature chemical biology (01.12.2012)
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Journal Article
Structure of NFAT1 bound as a dimer to the HIV-1 LTR κB element
Chen, Lin, Giffin, Michael J, Stroud, James C, Bates, Darren L, von Koenig, Konstanze D, Hardin, John
Published in Nature structural biology (01.10.2003)
Published in Nature structural biology (01.10.2003)
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Journal Article
항-CCR8 항체 및 이의 용도
RAUM TOBIAS, KIELCZEWSKA AGNIESZKA, BATES DARREN L, HONER JONAS KARL JOSEF, PIERCE NATHAN WILLIAM, WINKEL LISA, NOLAN STEVAUX OLIVIER, BLUEMEL CLAUDIA, DAHLHOFF CHRISTOPH, CHEN WENTAO
Year of Publication 08.02.2024
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Year of Publication 08.02.2024
Patent
T 세포 관여자 분자 및 이의 용도
RAUM TOBIAS, KIELCZEWSKA AGNIESZKA, BROZY JOHANNES, PENDZIALEK JOCHEN S, BATES DARREN L, HONER JONAS KARL JOSEF, WINKEL LISA, PIERCE NATHAN WILLIAM, BLUEMEL CLAUDIA, DAHLHOFF CHRISTOPH, MUENZ MARKUS, CHEN WENTAO
Year of Publication 14.02.2024
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Year of Publication 14.02.2024
Patent
Crystal structure of NFAT bound to the HIV-1 LTR tandem kappaB enhancer element
Bates, Darren L, Barthel, Kristen K B, Wu, Yongqing, Kalhor, Reza, Stroud, James C, Giffin, Michael J, Chen, Lin
Published in Structure (London) (01.05.2008)
Published in Structure (London) (01.05.2008)
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Journal Article
GLP-1 작용제와 조합하여 위 저해 펩타이드 수용체(GIPR)에 대한 결합 단백질을 이용하여 대사 장애를 치료하거나 또는 개선시키는 방법
LLOYD DAVID J, UMEDA AIKO, MIN XIAOSHAN, BATES DARREN L, WANG ZHULUN, SHI DONGHUI, MICHAELS MARK L, HAGER TODD, CHEN IRWIN, BONDARENKO PAVEL
Year of Publication 21.02.2020
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Year of Publication 21.02.2020
Patent
위 억제 펩티드 수용체 (GIPR)에 대한 결합 단백질을 GLP-1 효능제와 조합하여 사용하여 대사 장애를 치료하거나 개선시키는 방법
LLOYD DAVID J, YIE JUNMING, MIN XIAOSHAN, VENIANT ELLISON MURIELLE M, HO SHU YIN, SHI DONGHUI, KOMOROWSKI RENEE, MURAWSKY CHRISTOPHER, CLAVETTE BRANDON C. P, BATES DARREN L, FOLTZ IAN N, WANG ZHULUN, AGRAWAL NEERAJ, SIVITS JR. GLENN N, WANG JINGHONG
Year of Publication 04.10.2018
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Year of Publication 04.10.2018
Patent
Structural Basis of HIV-1 Activation by NF-κB—A Higher-Order Complex of p50:RelA Bound to the HIV-1 LTR
Stroud, James C., Oltman, Amy, Han, Aidong, Bates, Darren L., Chen, Lin
Published in Journal of molecular biology (16.10.2009)
Published in Journal of molecular biology (16.10.2009)
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Journal Article
Crystal Structure of NFAT Bound to the HIV-1 LTR Tandem κB Enhancer Element
Bates, Darren L., Barthel, Kristen K.B., Wu, Yongqing, Kalhor, Reza, Stroud, James C., Giffin, Michael J., Chen, Lin
Published in Structure (London) (07.05.2008)
Published in Structure (London) (07.05.2008)
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Journal Article