MLi-2, a Potent, Selective, and Centrally Active Compound for Exploring the Therapeutic Potential and Safety of LRRK2 Kinase Inhibition
Fell, Matthew J, Mirescu, Christian, Basu, Kallol, Cheewatrakoolpong, Boonlert, DeMong, Duane E, Ellis, J Michael, Hyde, Lynn A, Lin, Yinghui, Markgraf, Carrie G, Mei, Hong, Miller, Michael, Poulet, Frederique M, Scott, Jack D, Smith, Michelle D, Yin, Zhizhang, Zhou, Xiaoping, Parker, Eric M, Kennedy, Matthew E, Morrow, John A
Published in The Journal of pharmacology and experimental therapeutics (01.12.2015)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2015)
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Evolution of the Total Synthesis of (−)-Okilactomycin Exploiting a Tandem Oxy-Cope Rearrangement/Oxidation, a Petasis−Ferrier Union/Rearrangement, and Ring-Closing Metathesis
Smith, Amos B, Bosanac, Todd, Basu, Kallol
Published in Journal of the American Chemical Society (18.02.2009)
Published in Journal of the American Chemical Society (18.02.2009)
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Total Syntheses of the Assigned Structures of Lituarines B and C
Smith, Amos B, Duffey, Matthew O, Basu, Kallol, Walsh, Shawn P, Suennemann, Hans W, Frohn, Michael
Published in Journal of the American Chemical Society (16.01.2008)
Published in Journal of the American Chemical Society (16.01.2008)
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The Leader's Role in Managing Change: Five Cases of Technology-Enabled Business Transformation
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Discovery of a 3‑(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity
Scott, Jack D, DeMong, Duane E, Greshock, Thomas J, Basu, Kallol, Dai, Xing, Harris, Joel, Hruza, Alan, Li, Sarah W, Lin, Sue-Ing, Liu, Hong, Macala, Megan K, Hu, Zhiyong, Mei, Hong, Zhang, Honglu, Walsh, Paul, Poirier, Marc, Shi, Zhi-Cai, Xiao, Li, Agnihotri, Gautam, Baptista, Marco A. S, Columbus, John, Fell, Matthew J, Hyde, Lynn A, Kuvelkar, Reshma, Lin, Yinghui, Mirescu, Christian, Morrow, John A, Yin, Zhizhang, Zhang, Xiaoping, Zhou, Xiaoping, Chang, Ronald K, Embrey, Mark W, Sanders, John M, Tiscia, Heather E, Drolet, Robert E, Kern, Jonathan T, Sur, Sylvie M, Renger, John J, Bilodeau, Mark T, Kennedy, Matthew E, Parker, Eric M, Stamford, Andrew W, Nargund, Ravi, McCauley, John A, Miller, Michael W
Published in Journal of medicinal chemistry (13.04.2017)
Published in Journal of medicinal chemistry (13.04.2017)
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Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 4: Formylation–Cyclization as a Flow–Batch Process Leads to Significant Improvements in Process Mass Intensity (PMI) and CO Generated versus the Batch–Batch Process
Otte, Douglas A. L, Basu, Kallol, Jellett, Lisa, Whittington, Michael, Spencer, Glenn, Burris, Matthew, Corcoran, Emily B, Stone, Kevin, Nappi, Jarod, Arvary, Rebecca A, Donoghue, David, Ren, Hong, Maloney, Kevin M, Naber, John R
Published in Organic process research & development (20.11.2020)
Published in Organic process research & development (20.11.2020)
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Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 1: Introduction and Process Overview
Ren, Hong, Maloney, Kevin M, Basu, Kallol, Di Maso, Michael J, Humphrey, Guy R, Peng, Feng, Desmond, Richard, Otte, Douglas A. L, Alwedi, Embarek, Liu, Wenjun, Zhang, Si-Wei, Song, Siqing, Arvary, Rebecca A, Zompa, Michael A, Lehnherr, Dan, Martin, Gary E, Chang, Hsieh Yao D, Mohan, Anne E, Guzman, Francisco J, Jellett, Lisa, Lee, Alfred Y, Spencer, Glenn, Fisher, Elizabeth S, Naber, John R, Gao, Hong, Lohani, Sachin, Ruck, Rebecca T, Campeau, Louis-Charles
Published in Organic process research & development (20.11.2020)
Published in Organic process research & development (20.11.2020)
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Total Synthesis of (−)-Okilactomycin
Smith, Amos B, Basu, Kallol, Bosanac, Todd
Published in Journal of the American Chemical Society (05.12.2007)
Published in Journal of the American Chemical Society (05.12.2007)
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Journal Article
Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 3: Development of a One-Pot Formylation–Cyclization Sequence to the Diaminopyrimidine Core
Basu, Kallol, Lehnherr, Dan, Martin, Gary E, Desmond, Richard A, Lam, Yu-hong, Peng, Feng, Chung, John Y. L, Arvary, Rebecca A, Zompa, Michael A, Zhang, Si-Wei, Liu, Jinchu, Dance, Zachary E. X, Larpent, Patrick, Cohen, Ryan D, Guzman, Francisco J, Rogus, Nicholas J, Di Maso, Michael J, Ren, Hong, Maloney, Kevin M
Published in Organic process research & development (20.11.2020)
Published in Organic process research & development (20.11.2020)
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Can We Make Small Molecules Lean? Optimization of a Highly Lipophilic TarO Inhibitor
Mandal, Mihirbaran, Tan, Zheng, Madsen-Duggan, Christina, Buevich, Alexei V, Caldwell, John P, Dejesus, Reynalda, Flattery, Amy, Garlisi, Charles G, Gill, Charles, Ha, Sookhee Nicole, Ho, Ginny, Koseoglu, Sandra, Labroli, Marc, Basu, Kallol, Lee, Sang Ho, Liang, Lianzhu, Liu, Jenny, Mayhood, Todd, McGuinness, Debra, McLaren, David G, Wen, Xiujuan, Parmee, Emma, Rindgen, Diane, Roemer, Terry, Sheth, Payal, Tawa, Paul, Tata, James, Yang, Christine, Yang, Shu-Wei, Xiao, Li, Wang, Hao, Tan, Christopher, Tang, Haifeng, Walsh, Paul, Walsh, Erika, Wu, Jin, Su, Jing
Published in Journal of medicinal chemistry (11.05.2017)
Published in Journal of medicinal chemistry (11.05.2017)
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페녹시 디아미노피리미딘 화합물의 신규 합성 방법
DI MASO MICHAEL JAMES, LEE ALFRED Y, CHUNG JOHN Y.L, BASU KALLOL, MALONEY KEVIN M, DESMOND RICHARD, LEHNHERR DAN, REN HONG, WEISEL MARK, LARPENT PATRICK, PENG FENG, ZHANG SIWEI, HUMPHREY GUY R
Year of Publication 14.01.2021
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Year of Publication 14.01.2021
Patent
Evaluation of possible intramolecular [4+2] cycloaddition routes for assembling the central tetracyclic core of the potent marine antiinflammatory agent mangicol A
Pichlmair, Stefan, de Lera Ruiz, Manuel, Basu, Kallol, Paquette, Leo A.
Published in Tetrahedron (29.05.2006)
Published in Tetrahedron (29.05.2006)
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Journal Article
Evaluation of possible intramolecular [4+2] cycloaddition routes for assembling the central tetracyclic core of the potent marine antfinflammatory agent mangicol A
Pichlmair, Stefan, de Lera Ruiz, Manuel, Basu, Kallol, Paquette, Leo A.
Published in Tetrahedron (29.05.2006)
Published in Tetrahedron (29.05.2006)
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Pyrazoloquinolines as PDE10A inhibitors: Discovery of a tool compound
McElroy, William T., Tan, Zheng, Basu, Kallol, Yang, Shu-Wei, Smotryski, Jennifer, Ho, Ginny D., Tulshian, Deen, Greenlee, William J., Mullins, Deborra, Guzzi, Mario, Zhang, Xiaoping, Bleickardt, Carina, Hodgson, Robert
Published in Bioorganic & medicinal chemistry letters (01.02.2012)
Published in Bioorganic & medicinal chemistry letters (01.02.2012)
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