PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene–disease associations
Denny, Joshua C., Ritchie, Marylyn D., Basford, Melissa A., Pulley, Jill M., Bastarache, Lisa, Brown-Gentry, Kristin, Wang, Deede, Masys, Dan R., Roden, Dan M., Crawford, Dana C.
Published in Bioinformatics (01.05.2010)
Published in Bioinformatics (01.05.2010)
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Robust Replication of Genotype-Phenotype Associations across Multiple Diseases in an Electronic Medical Record
Ritchie, Marylyn D., Denny, Joshua C., Crawford, Dana C., Ramirez, Andrea H., Weiner, Justin B., Pulley, Jill M., Basford, Melissa A., Brown-Gentry, Kristin, Balser, Jeffrey R., Masys, Daniel R., Haines, Jonathan L., Roden, Dan M.
Published in American journal of human genetics (09.04.2010)
Published in American journal of human genetics (09.04.2010)
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Journal Article
Demonstrating paths for unlocking the value of cloud genomics through cross cohort analysis
Deflaux, Nicole, Selvaraj, Margaret Sunitha, Condon, Henry Robert, Mayo, Kelsey, Haidermota, Sara, Basford, Melissa A., Lunt, Chris, Philippakis, Anthony A., Roden, Dan M., Denny, Joshua C., Musick, Anjene, Collins, Rory, Allen, Naomi, Effingham, Mark, Glazer, David, Natarajan, Pradeep, Bick, Alexander G.
Published in Nature communications (05.09.2023)
Published in Nature communications (05.09.2023)
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Predicting warfarin dosage in European-Americans and African-Americans using DNA samples linked to an electronic health record
Ramirez, Andrea H, Shi, Yaping, Schildcrout, Jonathan S, Delaney, Jessica T, Xu, Hua, Oetjens, Matthew T, Zuvich, Rebecca L, Basford, Melissa A, Bowton, Erica, Jiang, Min, Speltz, Peter, Zink, Raquel, Cowan, James, Pulley, Jill M, Ritchie, Marylyn D, Masys, Daniel R, Roden, Dan M, Crawford, Dana C, Denny, Joshua C
Published in Pharmacogenomics (01.03.2012)
Published in Pharmacogenomics (01.03.2012)
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Journal Article
Modulators of normal electrocardiographic intervals identified in a large electronic medical record
Ramirez, Andrea H., MD, Schildcrout, Jonathan S., PhD, Blakemore, Dana L., MS, Masys, Dan R., MD, Pulley, Jill M., MBA, Basford, Melissa A., MBA, Roden, Dan M., MD, FHRS, Denny, Joshua C., MD, MS
Published in Heart rhythm (01.02.2011)
Published in Heart rhythm (01.02.2011)
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Journal Article
Admixture mapping and subsequent fine-mapping suggests a biologically relevant and novel association on chromosome 11 for type 2 diabetes in African Americans
Jeff, Janina M, Armstrong, Loren L, Ritchie, Marylyn D, Denny, Joshua C, Kho, Abel N, Basford, Melissa A, Wolf, Wendy A, Pacheco, Jennifer A, Li, Rongling, Chisholm, Rex L, Roden, Dan M, Hayes, M Geoffrey, Crawford, Dana C
Published in PloS one (03.03.2014)
Published in PloS one (03.03.2014)
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The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future
Gottesman, Omri, Kuivaniemi, Helena, Tromp, Gerard, Faucett, W. Andrew, Li, Rongling, Manolio, Teri A., Sanderson, Saskia C., Kannry, Joseph, Zinberg, Randi, Basford, Melissa A., Brilliant, Murray, Carey, David J., Chisholm, Rex L., Chute, Christopher G., Connolly, John J., Crosslin, David, Denny, Joshua C., Gallego, Carlos J., Haines, Jonathan L., Hakonarson, Hakon, Harley, John, Jarvik, Gail P., Kohane, Isaac, Kullo, Iftikhar J., Larson, Eric B., McCarty, Catherine, Ritchie, Marylyn D., Roden, Dan M., Smith, Maureen E., Böttinger, Erwin P., Williams, Marc S.
Published in Genetics in medicine (01.10.2013)
Published in Genetics in medicine (01.10.2013)
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Journal Article
Genome- and Phenome-Wide Analyses of Cardiac Conduction Identifies Markers of Arrhythmia Risk
RITCHIE, Marylyn D, DENNY, Joshua C, BRADFORD, Yuki, RASMUSSEN, Luke V, PATHAK, Jyotishman, CHUTE, Christopher G, KULLO, Iftikhar J, MCCARTY, Catherine A, CHISHOLM, Rex L, KHO, Abel N, CARLSON, Christopher S, LARSON, Eric B, ZUVICH, Rebecca L, JARVIK, Gail P, SOTOODEHNIA, Nona, MANOLIO, Teri A, RONGLING LI, MASYS, Daniel R, HAINES, Jonathan L, RODEN, Dan M, CRAWFORD, Dana C, SCHILDCROUT, Jonathan S, BASTARACHE, Lisa, RAMIREZ, Andrea H, MOSLEY, Jonathan D, PULLEY, Jill M, BASFORD, Melissa A
Published in Circulation (New York, N.Y.) (02.04.2013)
Published in Circulation (New York, N.Y.) (02.04.2013)
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Journal Article
Variants Near FOXE1 Are Associated with Hypothyroidism and Other Thyroid Conditions: Using Electronic Medical Records for Genome- and Phenome-wide Studies
Denny, Joshua C., Crawford, Dana C., Ritchie, Marylyn D., Bielinski, Suzette J., Basford, Melissa A., Bradford, Yuki, Chai, High Seng, Bastarache, Lisa, Zuvich, Rebecca, Peissig, Peggy, Carrell, David, Ramirez, Andrea H., Pathak, Jyotishman, Wilke, Russell A., Rasmussen, Luke, Wang, Xiaoming, Pacheco, Jennifer A., Kho, Abel N., Hayes, M. Geoffrey, Weston, Noah, Matsumoto, Martha, Kopp, Peter A., Newton, Katherine M., Jarvik, Gail P., Li, Rongling, Manolio, Teri A., Kullo, Iftikhar J., Chute, Christopher G., Chisholm, Rex L., Larson, Eric B., McCarty, Catherine A., Masys, Daniel R., Roden, Dan M., de Andrade, Mariza
Published in American journal of human genetics (07.10.2011)
Published in American journal of human genetics (07.10.2011)
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Journal Article
Identification of Genomic Predictors of Atrioventricular Conduction: Using Electronic Medical Records as a Tool for Genome Science
DENNY, Joshua C, RITCHIE, Marylyn D, CRAWFORD, Dana C, SCHILDCROUT, Jonathan S, RAMIREZ, Andrea H, PULLEY, Jill M, BASFORD, Melissa A, MASYS, Daniel R, HAINES, Jonathan L, RODEN, Dan M
Published in Circulation (New York, N.Y.) (16.11.2010)
Published in Circulation (New York, N.Y.) (16.11.2010)
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A prognostic model based on readily available clinical data enriched a pre-emptive pharmacogenetic testing program
Schildcrout, Jonathan S, Shi, Yaping, Danciu, Ioana, Bowton, Erica, Field, Julie R, Pulley, Jill M, Basford, Melissa A, Gregg, William, Cowan, James D, Harrell, Frank E, Roden, Dan M, Peterson, Josh F, Denny, Joshua C
Published in Journal of clinical epidemiology (01.04.2016)
Published in Journal of clinical epidemiology (01.04.2016)
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The All of Us Data and Research Center: Creating a Secure, Scalable, and Sustainable Ecosystem for Biomedical Research
Mayo, Kelsey R, Basford, Melissa A, Carroll, Robert J, Dillon, Moira, Fullen, Heather, Leung, Jesse, Master, Hiral, Rura, Shimon, Sulieman, Lina, Kennedy, Nan, Banks, Eric, Bernick, David, Gauchan, Asmita, Lichtenstein, Lee, Mapes, Brandy M, Marginean, Kayla, Nyemba, Steve L, Ramirez, Andrea, Rotundo, Charissa, Wolfe, Keri, Xia, Weiyi, Azuine, Romuladus E, Cronin, Robert M, Denny, Joshua C, Kho, Abel, Lunt, Christopher, Malin, Bradley, Natarajan, Karthik, Wilkins, Consuelo H, Xu, Hua, Hripcsak, George, Roden, Dan M, Philippakis, Anthony A, Glazer, David, Harris, Paul A
Published in Annual review of biomedical data science (10.08.2023)
Published in Annual review of biomedical data science (10.08.2023)
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Journal Article
Facilitating pharmacogenetic studies using electronic health records and natural-language processing: a case study of warfarin
Xu, Hua, Jiang, Min, Oetjens, Matt, Bowton, Erica A, Ramirez, Andrea H, Jeff, Janina M, Basford, Melissa A, Pulley, Jill M, Cowan, James D, Wang, Xiaoming, Ritchie, Marylyn D, Masys, Daniel R, Roden, Dan M, Crawford, Dana C, Denny, Joshua C
Published in Journal of the American Medical Informatics Association : JAMIA (01.07.2011)
Published in Journal of the American Medical Informatics Association : JAMIA (01.07.2011)
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Journal Article
Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network
Malinowski, Jennifer R, Denny, Joshua C, Bielinski, Suzette J, Basford, Melissa A, Bradford, Yuki, Peissig, Peggy L, Carrell, David, Crosslin, David R, Pathak, Jyotishman, Rasmussen, Luke, Pacheco, Jennifer, Kho, Abel, Newton, Katherine M, Li, Rongling, Kullo, Iftikhar J, Chute, Christopher G, Chisholm, Rex L, Jarvik, Gail P, Larson, Eric B, McCarty, Catherine A, Masys, Daniel R, Roden, Dan M, de Andrade, Mariza, Ritchie, Marylyn D, Crawford, Dana C
Published in PloS one (01.12.2014)
Published in PloS one (01.12.2014)
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Journal Article
Generalization of Variants Identified by Genome‐Wide Association Studies for Electrocardiographic Traits in African Americans
Jeff, Janina M., Ritchie, Marylyn D., Denny, Joshua C., Kho, Abel N., Ramirez, Andrea H., Crosslin, David, Armstrong, Loren, Basford, Melissa A., Wolf, Wendy A., Pacheco, Jennifer A., Chisholm, Rex L., Roden, Dan M., Hayes, M. Geoffrey, Crawford, Dana C.
Published in Annals of human genetics (01.07.2013)
Published in Annals of human genetics (01.07.2013)
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Assessment of a pharmacogenomic marker panel in a polypharmacy population identified from electronic medical records
Oetjens, Matthew T, Denny, Joshua C, Ritchie, Marylyn D, Gillani, Niloufar B, Richardson, Danielle M, Restrepo, Nicole A, Pulley, Jill M, Dilks, Holli H, Basford, Melissa A, Bowton, Erica, Masys, Dan R, Wilke, Russell A, Roden, Dan M, Crawford, Dana C
Published in Pharmacogenomics (01.05.2013)
Published in Pharmacogenomics (01.05.2013)
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An analytical approach to characterize morbidity profile dissimilarity between distinct cohorts using electronic medical records
Schildcrout, Jonathan S., Basford, Melissa A., Pulley, Jill M., Masys, Daniel R., Roden, Dan M., Wang, Deede, Chute, Christopher G., Kullo, Iftikhar J., Carrell, David, Peissig, Peggy, Kho, Abel, Denny, Joshua C.
Published in Journal of biomedical informatics (01.12.2010)
Published in Journal of biomedical informatics (01.12.2010)
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Enabling high-throughput genotype-phenotype associations in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project as part of the Population Architecture using Genomics and Epidemiology (PAGE) study
Bush, William S, Boston, Jonathan, Pendergrass, Sarah A, Dumitrescu, Logan, Goodloe, Robert, Brown-Gentry, Kristin, Wilson, Sarah, McClellan, Bob, Torstenson, Eric, Basford, Melissa A, Spencer, Kylee L, Ritchie, Marylyn D, Crawford, Dana C
Published in Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing (2013)
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Published in Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing (2013)
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Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data
Denny, Joshua C, Bastarache, Lisa, Ritchie, Marylyn D, Carroll, Robert J, Zink, Raquel, Mosley, Jonathan D, Field, Julie R, Pulley, Jill M, Ramirez, Andrea H, Bowton, Erica, Basford, Melissa A, Carrell, David S, Peissig, Peggy L, Kho, Abel N, Pacheco, Jennifer A, Rasmussen, Luke V, Crosslin, David R, Crane, Paul K, Pathak, Jyotishman, Bielinski, Suzette J, Pendergrass, Sarah A, Xu, Hua, Hindorff, Lucia A, Li, Rongling, Manolio, Teri A, Chute, Christopher G, Chisholm, Rex L, Larson, Eric B, Jarvik, Gail P, Brilliant, Murray H, McCarty, Catherine A, Kullo, Iftikhar J, Haines, Jonathan L, Crawford, Dana C, Masys, Daniel R, Roden, Dan M
Published in Nature biotechnology (01.12.2013)
Published in Nature biotechnology (01.12.2013)
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Optimizing drug outcomes through pharmacogenetics: a case for preemptive genotyping
Schildcrout, J S, Denny, J C, Bowton, E, Gregg, W, Pulley, J M, Basford, M A, Cowan, J D, Xu, H, Ramirez, A H, Crawford, D C, Ritchie, M D, Peterson, J F, Masys, D R, Wilke, R A, Roden, D M
Published in Clinical pharmacology and therapeutics (01.08.2012)
Published in Clinical pharmacology and therapeutics (01.08.2012)
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