Overt Thyroid Dysfunction and Anti-Thyroid Antibodies Predict Response to Anti-PD-1 Immunotherapy in Cancer Patients
Basak, Edwin A, van der Meer, Jan W M, Hurkmans, Daan P, Schreurs, Marco W J, Oomen-de Hoop, Esther, van der Veldt, Astrid A M, Bins, Sander, Joosse, Arjen, Koolen, Stijn L W, Debets, Reno, Peeters, Robin P, Aerts, Joachim G J V, Mathijssen, Ron H J, Medici, Marco
Published in Thyroid (New York, N.Y.) (01.07.2020)
Published in Thyroid (New York, N.Y.) (01.07.2020)
Get more information
Journal Article
Correlation between nivolumab exposure and treatment outcomes in non–small-cell lung cancer
Basak, Edwin A., Koolen, Stijn L.W., Hurkmans, Daan P., Schreurs, Marco W.J., Bins, Sander, Oomen – de Hoop, Esther, Wijkhuijs, Annemarie J.M., Besten, Ilse den, Sleijfer, Stefan, Debets, Reno, van der Veldt, Astrid A.M., Aerts, Joachim G.J.V., Mathijssen, Ron H.J.
Published in European journal of cancer (1990) (01.03.2019)
Published in European journal of cancer (1990) (01.03.2019)
Get full text
Journal Article
Association between single-nucleotide polymorphisms and adverse events in nivolumab-treated non-small cell lung cancer patients
Bins, Sander, Basak, Edwin A., el Bouazzaoui, Samira, Koolen, Stijn L. W., Oomen – de Hoop, E., van der Leest, Cor H., van der Veldt, Astrid A. M., Sleijfer, Stefan, Debets, Reno, van Schaik, Ron H. N., Aerts, Joachim G. J. V., Mathijssen, Ron H. J.
Published in British journal of cancer (01.05.2018)
Published in British journal of cancer (01.05.2018)
Get full text
Journal Article
Granzyme B is correlated with clinical outcome after PD-1 blockade in patients with stage IV non-small-cell lung cancer
Hurkmans, Daan P., Basak, Edwin A., Schepers, Nina, Oomen-De Hoop, Esther, Van der Leest, Cor H., El Bouazzaoui, Samira, Bins, Sander, Koolen, Stijn L. W., Sleijfer, Stefan, Van der Veldt, Astrid A. M., Debets, Reno, Van Schaik, Ron H. N., Aerts, Joachim G. J. V., Mathijssen, Ron H. J.
Published in Journal for immunotherapy of cancer (01.05.2020)
Published in Journal for immunotherapy of cancer (01.05.2020)
Get full text
Journal Article
A prospective cohort study on the pharmacokinetics of nivolumab in metastatic non-small cell lung cancer, melanoma, and renal cell cancer patients
Hurkmans, Daan P, Basak, Edwin A, van Dijk, Tanja, Mercieca, Darlene, Schreurs, Marco W J, Wijkhuijs, Annemarie J M, Bins, Sander, Hoop, Esther Oomen-de, Debets, Reno, Joerger, Markus, Odink, Arlette, van der Veldt, Astrid A M, van der Leest, Cor H, Aerts, Joachim G J V, Mathijssen, Ron H J, Koolen, Stijn L W
Published in Journal for immunotherapy of cancer (19.07.2019)
Published in Journal for immunotherapy of cancer (19.07.2019)
Get full text
Journal Article
The course of C-peptide levels in patients developing diabetes during anti-PD-1 therapy
Basak, Edwin A., de Joode, Karlijn, Uyl, Tom J.J., van der Wal, Ronald, Schreurs, Marco W.J., van den Berg, Sjoerd A.A., Oomen-de Hoop, Esther, van der Leest, Cor H., Chaker, Layal, Feelders, Richard A., van der Veldt, Astrid A.M., Joosse, Arjen, Koolen, Stijn L.W., Aerts, Joachim G.J.V., Mathijssen, Ron H.J., Bins, Sander
Published in Biomedicine & pharmacotherapy (01.12.2022)
Published in Biomedicine & pharmacotherapy (01.12.2022)
Get full text
Journal Article
CD45RA + CCR7 - CD8 T cells lacking co-stimulatory receptors demonstrate enhanced frequency in peripheral blood of NSCLC patients responding to nivolumab
Kunert, Andre, Basak, Edwin A, Hurkmans, Daan P, Balcioglu, Hayri E, Klaver, Yarne, van Brakel, Mandy, Oostvogels, Astrid A M, Lamers, Cor H J, Bins, Sander, Koolen, Stijn L W, van der Veldt, Astrid A M, Sleijfer, Stefan, Mathijssen, Ron H J, Aerts, Joachim G J V, Debets, Reno
Published in Journal for immunotherapy of cancer (08.06.2019)
Published in Journal for immunotherapy of cancer (08.06.2019)
Get full text
Journal Article
Prospective real-world study on the pharmacokinetics of pembrolizumab in patients with solid tumors
Hurkmans, Daan P., Sassen, Sebastiaan D.T., de Joode, Karlijn, Putter, Lisanne, Basak, Edwin A., Wijkhuijs, Annemarie J.M., Joerger, Markus, Debets, Reno, Koch, Birgit C.P., Van der Leest, Cor H., Schreurs, Marco W.J., van der Veldt, Astrid A.M., Aerts, Joachim G.J.V., Mathijssen, Ron H.J., Koolen, Stijn L.W.
Published in Journal for immunotherapy of cancer (01.06.2021)
Published in Journal for immunotherapy of cancer (01.06.2021)
Get full text
Journal Article
Blood-based kinase activity profiling: a potential predictor of response to immune checkpoint inhibition in metastatic cancer
Hurkmans, Daan P, Verdegaal, Els M E, Hogan, Sabrina A, de Wijn, Rik, Hovestad, Lies, van den Heuvel, Dianne M A, Ruijtenbeek, Rob, Welters, Marij J P, van Brakel, Mandy, Basak, Edwin A, Pinedo, Herbert M, Lamers, Cor H J, van de Werken, Harmen J G, Groten, John P, Debets, Reno, Levesque, Mitchell P, Dummer, Reinhard, Kapiteijn, Ellen, Mathijssen, Ron H J, Aerts, Joachim G J V, van der Burg, Sjoerd H
Published in Journal for immunotherapy of cancer (01.12.2020)
Published in Journal for immunotherapy of cancer (01.12.2020)
Get full text
Journal Article
Review - The impact of pharmacogenetics on the outcome of immune checkpoint inhibitors
de Joode, Karlijn, Heersche, Niels, Basak, Edwin A, Bins, Sander, van der Veldt, Astrid A M, van Schaik, Ron H N, Mathijssen, Ron H J
Published in Cancer treatment reviews (01.01.2024)
Published in Cancer treatment reviews (01.01.2024)
Get full text
Journal Article
Associations between patient and disease characteristics and severe adverse events during immune checkpoint inhibitor treatment: An observational study
Basak, Edwin A., Vermeer, Niels S., de Joode, Karlijn, Hurkmans, Daan P., Velthuis, Dorian E.M., Oomen-de Hoop, Esther, Schreurs, Marco W.J., Bins, Sander, Koolen, Stijn L.W., Debets, Reno, van der Veldt, Astrid A.M., Aerts, Joachim G.J.V., Joosse, Arjen, Mathijssen, Ron H.J.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
Get full text
Journal Article
Development of an Enzyme-Linked Immune Sorbent Assay to Measure Nivolumab and Pembrolizumab Serum Concentrations
Basak, Edwin A, Wijkhuijs, Annemarie J M, Mathijssen, Ron H J, Koolen, Stijn L W, Schreurs, Marco W J
Published in Therapeutic drug monitoring (01.10.2018)
Published in Therapeutic drug monitoring (01.10.2018)
Get more information
Journal Article
Retrospective validation of a pretreatment serum protein profile in metastatic non-small cell lung cancer patients treated with a pembrolizumab containing regime as first line of treatment
Mellema, Wouter W., Basak, Edwin A., Roder, Heinrich, Roder, Joanna, Georgantas, Robert W., Smit, Egbert F., Aerts, Joachim
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
Get full text
Journal Article
Correlation between nivolumab exposure and treatment outcome in NSCLC
Koolen, Stijn L.W., Basak, Edwin A., Hurkmans, Daan, Schreurs, Marco W.J., Bins, Sander, De Hoop, Esther Oomen, Wijkhuis, Annemarie JM, Den Besten, Ilse, Sleijfer, Stefan, Debets, Reno, Van Der Veldt, Astrid, Aerts, Joachim, Mathijssen, Ron H.J.
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
Get full text
Journal Article
Identifying t cell profiles that associate with clinical response to anti-PD-1 treatment in non-small cell lung carcinoma (NSCLC) patients
Kunert, Andre, Basak, Edwin A., Hurkmans, Daan, Klaver, Yarne, van Brakel, Mandy, Oostvogels, Astrid, Lamers, Cor, Bins, Sander, Koolen, Stijn L.W., Van Der Veldt, Astrid, Sleijfer, Stefan, Mathijssen, Ron H.J., Aerts, Joachim G.J.V., Debets, Reno
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
Get full text
Journal Article
Blood-based multiplex kinase activity profiling as a predictive marker for clinical response to checkpoint blockade in advanced melanoma
Hurkmans, Daan, Verdegaal, Els M.E., Schindler, Sabrina A., Basak, Edwin A., van den Heuvel, Dianne M.A., de Wijn, Rik, Ruijtenbeek, Rob, Groten, John P., Dummer, Reinhard, Koolen, Stijn L.W., Welters, Marij J.P., Mathijssen, Ron H.J., Kapiteijn, Ellen, Aerts, Joachim G.J.V., Levesque, Mitchell P., van der Burg, Sjoerd H.
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
Get full text
Journal Article