Tropomyosin Structure, Function, and Interactions: A Dynamic Regulator
Hitchcock-DeGregori, Sarah E., Barua, Bipasha
Published in Fibrous Proteins: Structures and Mechanisms (01.01.2017)
Published in Fibrous Proteins: Structures and Mechanisms (01.01.2017)
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Book Chapter
Journal Article
Positive cardiac inotrope omecamtiv mecarbil activates muscle despite suppressing the myosin working stroke
Woody, Michael S., Greenberg, Michael J., Barua, Bipasha, Winkelmann, Donald A., Goldman, Yale E., Ostap, E. Michael
Published in Nature communications (21.09.2018)
Published in Nature communications (21.09.2018)
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Journal Article
Myosin with hypertrophic cardiac mutation R712L has a decreased working stroke which is rescued by omecamtiv mecarbil
Snoberger, Aaron, Barua, Bipasha, Atherton, Jennifer L, Shuman, Henry, Forgacs, Eva, Goldman, Yale E, Winkelmann, Donald A, Ostap, E Michael
Published in eLife (19.02.2021)
Published in eLife (19.02.2021)
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Journal Article
Folding Dynamics and Pathways of the Trp-Cage Miniproteins
Byrne, Aimee, Williams, D. Victoria, Barua, Bipasha, Hagen, Stephen J, Kier, Brandon L, Andersen, Niels H
Published in Biochemistry (Easton) (30.09.2014)
Published in Biochemistry (Easton) (30.09.2014)
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Journal Article
A Periodic Pattern of Evolutionarily Conserved Basic and Acidic Residues Constitutes the Binding Interface of Actin-Tropomyosin
Barua, Bipasha, Fagnant, Patricia M., Winkelmann, Donald A., Trybus, Kathleen M., Hitchcock-DeGregori, Sarah E.
Published in The Journal of biological chemistry (05.04.2013)
Published in The Journal of biological chemistry (05.04.2013)
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Journal Article
A molecular evolution approach to study the roles of tropomyosin in fission yeast
Cranz-Mileva, Susanne, Pamula, Melissa C, Barua, Bipasha, Desai, Brinda, Hong, Yaejee Hannah, Russell, Jacquelyn, Trent, Richard, Wang, Jianqiu, Walworth, Nancy C, Hitchcock-DeGregori, Sarah E
Published in PloS one (22.10.2013)
Published in PloS one (22.10.2013)
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Journal Article
Myosin with hypertrophic cardiomyopathy mutation M493I demonstrates altered crossbridge kinetics and force sensitivity despite normal working stroke
Cail, Robert C., Barua, Bipasha, Winkelmann, Donald A., Goldman, Yale E., Ostap, E. Michael
Published in Biophysical journal (08.02.2024)
Published in Biophysical journal (08.02.2024)
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Journal Article
Investigating the effects of tropomyosin mutations on its flexibility and interactions with filamentous actin using molecular dynamics simulation
Zheng, Wenjun, Hitchcock-DeGregori, Sarah E., Barua, Bipasha
Published in Journal of muscle research and cell motility (01.10.2016)
Published in Journal of muscle research and cell motility (01.10.2016)
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Journal Article
Regulation of Nonmuscle Myosin II by Tropomyosin
Barua, Bipasha, Nagy, Attila, Sellers, James R, Hitchcock-DeGregori, Sarah E
Published in Biochemistry (Easton) (24.06.2014)
Published in Biochemistry (Easton) (24.06.2014)
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Journal Article
Beta-Cardiac Myosin with an HCM Mutation (R712L) has an Inhibited Working Stroke that is Rescued by the Drug Omecamtiv Mecarbil
Snoberger, Aaron, Barua, Bipasha, Atherton, Jennifer L., Forgacs, Eva, Goldman, Yale E., Winkelmann, Donald A., Ostap, E. Michael
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
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Journal Article
Biochemical and Mechanical Properties of the S532P and R712L Cardiomyopathy Myosin Mutants
Xiong, Ailian, Liu, Yingying, Barua, Bipasha, Belknap, Betty, White, Howard, Winklemann, Donald, Forgacs, Eva
Published in Biophysical journal (03.02.2017)
Published in Biophysical journal (03.02.2017)
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Journal Article