Search Results - "Bartz, Ulrike" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes

Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes

by Benýšek, Jakub, Buša, Michal, Rubešová, Petra, Fanfrlík, Jindřich, Lepšík, Martin, Brynda, Jiří, Matoušková, Zuzana, Bartz, Ulrike, Horn, Martin, Gütschow, Michael, Mareš, Michael
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)

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Development of an active-site titrant for SARS-CoV-2 main protease as an indispensable tool for evaluating enzyme kinetics

Development of an active-site titrant for SARS-CoV-2 main protease as an indispensable tool for evaluating enzyme kinetics

by Voget, Rabea, Breidenbach, Julian, Claff, Tobias, Hingst, Alexandra, Sylvester, Katharina, Steinebach, Christian, Vu, Lan Phuong, Weiße, Renato H, Bartz, Ulrike, Sträter, Norbert, Müller, Christa E, Gütschow, Michael
Published in Acta pharmaceutica Sinica. B (01.05.2024)

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Chromenones as Multineurotargeting Inhibitors of Human Enzymes

Chromenones as Multineurotargeting Inhibitors of Human Enzymes

by Lemke, Carina, Christmann, Joscha, Yin, Jiafei, Alonso, José M, Serrano, Estefanía, Chioua, Mourad, Ismaili, Lhassane, Martínez-Grau, María Angeles, Beadle, Christopher D, Vetman, Tatiana, Dato, Florian M, Bartz, Ulrike, Elsinghorst, Paul W, Pietsch, Markus, Müller, Christa E, Iriepa, Isabel, Wille, Timo, Marco-Contelles, José, Gütschow, Michael
Published in ACS omega (24.12.2019)

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Coumarin as a structural component of substrates and probes for serine and cysteine proteases

Coumarin as a structural component of substrates and probes for serine and cysteine proteases

by Breidenbach, Julian, Bartz, Ulrike, Gütschow, Michael
Published in Biochimica et biophysica acta. Proteins and proteomics (01.09.2020)

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Cathepsin B: Active site mapping with peptidic substrates and inhibitors

Cathepsin B: Active site mapping with peptidic substrates and inhibitors

by Schmitz, Janina, Gilberg, Erik, Löser, Reik, Bajorath, Jürgen, Bartz, Ulrike, Gütschow, Michael
Published in Bioorganic & medicinal chemistry (01.01.2019)

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Coumarin as a structural component of substrates and probes for serine and cysteine proteases

Coumarin as a structural component of substrates and probes for serine and cysteine proteases

by Breidenbach, Julian, Bartz, Ulrike, Gütschow, Michael
Published in Biochimica et biophysica acta. Proteins and proteomics (13.05.2020)

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An Activity-Based Probe for Cathepsin K Imaging with Excellent Potency and Selectivity

An Activity-Based Probe for Cathepsin K Imaging with Excellent Potency and Selectivity

by Lemke, Carina, Benýšek, Jakub, Brajtenbach, Dominik, Breuer, Christian, Jílková, Adéla, Horn, Martin, Buša, Michal, Ulrychová, Lenka, Illies, Annika, Kubatzky, Katharina F, Bartz, Ulrike, Mareš, Michael, Gütschow, Michael
Published in Journal of medicinal chemistry (23.09.2021)

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Carbachol dimers with primary carbamate groups as homobivalent modulators of muscarinic receptors

Carbachol dimers with primary carbamate groups as homobivalent modulators of muscarinic receptors

by Matucci, Rosanna, Bellucci, Cristina, Martino, Maria Vittoria, Nesi, Marta, Manetti, Dina, Welzel, Jessica, Bartz, Ulrike, Holze, Janine, Tränkle, Christian, Mohr, Klaus, Mazzolari, Angelica, Vistoli, Giulio, Dei, Silvia, Teodori, Elisabetta, Romanelli, Maria Novella
Published in European journal of pharmacology (15.09.2020)

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N-Sulfonyl dipeptide nitriles as inhibitors of human cathepsin S: In silico design, synthesis and biochemical characterization

N-Sulfonyl dipeptide nitriles as inhibitors of human cathepsin S: In silico design, synthesis and biochemical characterization

by Lemke, Carina, Cianni, Lorenzo, Feldmann, Christian, Gilberg, Erik, Yin, Jiafei, dos Reis Rocho, Fernanda, de Vita, Daniela, Bartz, Ulrike, Bajorath, Jürgen, Montanari, Carlos A., Gütschow, Michael
Published in Bioorganic & medicinal chemistry letters (15.09.2020)

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Cathepsin B Inhibitors: Combining Dipeptide Nitriles with an Occluding Loop Recognition Element by Click Chemistry

Cathepsin B Inhibitors: Combining Dipeptide Nitriles with an Occluding Loop Recognition Element by Click Chemistry

by Schmitz, Janina, Li, Tianwei, Bartz, Ulrike, Gütschow, Michael
Published in ACS medicinal chemistry letters (10.03.2016)

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Synthesis and kinetic evaluation of ethyl acrylate and vinyl sulfone derived inhibitors for human cysteine cathepsins

Synthesis and kinetic evaluation of ethyl acrylate and vinyl sulfone derived inhibitors for human cysteine cathepsins

by Breuer, Christian, Lemke, Carina, Schmitz, Janina, Bartz, Ulrike, Gütschow, Michael
Published in Bioorganic & medicinal chemistry letters (15.06.2018)

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Active Site Mapping of Human Cathepsin F with Dipeptide Nitrile Inhibitors

Active Site Mapping of Human Cathepsin F with Dipeptide Nitrile Inhibitors

by Schmitz, Janina, Furtmann, Norbert, Ponert, Moritz, Frizler, Maxim, Löser, Reik, Bartz, Ulrike, Bajorath, Jürgen, Gütschow, Michael
Published in ChemMedChem (01.08.2015)

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The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents

The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents

by Keuler, Tim, Lemke, Carina, Elsinghorst, Paul W., Iriepa, Isabel, Chioua, Mourad, Martínez-Grau, María Angeles, Beadle, Christopher D., Vetman, Tatiana, López-Muñoz, Francisco, Wille, Timo, Bartz, Ulrike, Deuther-Conrad, Winnie, Marco-Contelles, José, Gütschow, Michael
Published in ACS pharmacology & translational science (11.11.2022)

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Design, characterization and cellular uptake studies of fluorescence-labeled prototypic cathepsin inhibitorsElectronic supplementary information (ESI) available: Inhibition assays for cathepsins L, S, K, and B, molecular docking, UV and fluorescence spectra, experimental HPLC procedure for log D7.4 estimation, as well as 13C NMR and 1H NMR spectra. See DOI: 10.1039/c5ob01613d

Design, characterization and cellular uptake studies of fluorescence-labeled prototypic cathepsin inhibitorsElectronic supplementary information (ESI) available: Inhibition assays for cathepsins L, S, K, and B, molecular docking, UV and fluorescence spectra, experimental HPLC procedure for log D7.4 estimation, as well as 13C NMR and 1H NMR spectra. See DOI: 10.1039/c5ob01613d

by Kohl, Franziska, Schmitz, Janina, Furtmann, Norbert, Schulz-Fincke, Anna-Christina, Mertens, Matthias D, Küppers, Jim, Benkhoff, Marcel, Tobiasch, Edda, Bartz, Ulrike, Bajorath, Jürgen, Stirnberg, Marit, Gütschow, Michael
Year of Publication 14.10.2015

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Design, characterization and cellular uptake studies of fluorescence-labeled prototypic cathepsin inhibitors

Design, characterization and cellular uptake studies of fluorescence-labeled prototypic cathepsin inhibitors

by Kohl, Franziska, Schmitz, Janina, Furtmann, Norbert, Schulz-Fincke, Anna-Christina, Mertens, Matthias D., Kueppers, Jim, Benkhoff, Marcel, Tobiasch, Edda, Bartz, Ulrike, Bajorath, Jurgen, Stirnberg, Marit, Guetschow, Michael
Published in Organic & biomolecular chemistry (01.01.2015)

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Active Site Mapping of Human CathepsinF with Dipeptide Nitrile Inhibitors

Active Site Mapping of Human CathepsinF with Dipeptide Nitrile Inhibitors

by Schmitz, Janina, Furtmann, Norbert, Ponert, Moritz, Frizler, Maxim, Loeser, Reik, Bartz, Ulrike, Bajorath, Juergen, Guetschow, Michael
Published in ChemMedChem (01.08.2015)

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3‑Cyano-3-aza-β-amino Acid Derivatives as Inhibitors of Human Cysteine Cathepsins

3‑Cyano-3-aza-β-amino Acid Derivatives as Inhibitors of Human Cysteine Cathepsins

by Schmitz, Janina, Beckmann, Anna-Madeleine, Dudic, Adela, Li, Tianwei, Sellier, Robert, Bartz, Ulrike, Gütschow, Michael
Published in ACS medicinal chemistry letters (09.10.2014)

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Steroidal isomers with uniform mass spectra of their per-TMS derivatives: Synthesis of 17-hydroxyandrostan-3-ones, androst-1-, and -4-ene-3,17-diols

Steroidal isomers with uniform mass spectra of their per-TMS derivatives: Synthesis of 17-hydroxyandrostan-3-ones, androst-1-, and -4-ene-3,17-diols

by Parr, Maria K., Zapp, Josef, Becker, Michael, Opfermann, Georg, Bartz, Ulrike, Schänzer, Wilhelm
Published in Steroids (01.06.2007)

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Steroidal isomers with uniform mass spectra of their per-TMS derivatives: Synthesis of 17-hydroxyandrostan3-ones, androst-1-, and -4-ene-3,17-diols

Steroidal isomers with uniform mass spectra of their per-TMS derivatives: Synthesis of 17-hydroxyandrostan3-ones, androst-1-, and -4-ene-3,17-diols

by PARR, Maria K, ZAPP, Josef, BECKER, Michael, OPFERMANN, Georg, BARTZ, Ulrike, SCHÄNZER, Wilhelm
Published in Steroids (2007)

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Pyridyl-Substituted Tetrahydrocyclopropa[a]naphthalenes: Highly Active and Selective Inhibitors of P450 arom

Pyridyl-Substituted Tetrahydrocyclopropa[a]naphthalenes: Highly Active and Selective Inhibitors of P450 arom

by Hartmann, Rolf W, Bayer, Herbert, Gruen, Gertrud, Sergejew, Tom, Bartz, Ulrike, Mitrenga, Markus
Published in Journal of medicinal chemistry (01.06.1995)

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