The Immune Microenvironment in Pancreatic Cancer
Huber, Magdalena, Brehm, Corinna U, Gress, Thomas M, Buchholz, Malte, Alashkar Alhamwe, Bilal, von Strandmann, Elke Pogge, Slater, Emily P, Bartsch, Jörg W, Bauer, Christian, Lauth, Matthias
Published in International journal of molecular sciences (01.10.2020)
Published in International journal of molecular sciences (01.10.2020)
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ADAM8 in invasive cancers: links to tumor progression, metastasis, and chemoresistance
Conrad, Catharina, Benzel, Julia, Dorzweiler, Kristina, Cook, Lena, Schlomann, Uwe, Zarbock, Alexander, Slater, Emily P, Nimsky, Christopher, Bartsch, Jörg W
Published in Clinical science (1979) (15.01.2019)
Published in Clinical science (1979) (15.01.2019)
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ADAM12 induces EMT and promotes cell migration, invasion and proliferation in pituitary adenomas via EGFR/ERK signaling pathway
Wang, Junwen, Zhang, Zhuo, Li, Ran, Mao, Feng, Sun, Wei, Chen, Juan, Zhang, Huaqiu, Bartsch, Jörg-W., Shu, Kai, Lei, Ting
Published in Biomedicine & pharmacotherapy (01.01.2018)
Published in Biomedicine & pharmacotherapy (01.01.2018)
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Molecular profiling of the tumor microenvironment in glioblastoma patients: correlation of microglia/macrophage polarization state with metalloprotease expression profiles and survival
Gjorgjevski, Marko, Hannen, Ricarda, Carl, Barbara, Li, Yu, Landmann, Emilie, Buchholz, Malte, Bartsch, Jörg W, Nimsky, Christopher
Published in Bioscience reports (28.06.2019)
Published in Bioscience reports (28.06.2019)
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Metalloprotease inhibitor profiles of human ADAM8 in vitro and in cell-based assays
Schlomann, Uwe, Dorzweiler, Kristina, Nuti, Elisa, Tuccinardi, Tiziano, Rossello, Armando, Bartsch, Jörg W.
Published in Biological chemistry (27.05.2019)
Published in Biological chemistry (27.05.2019)
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Journal Article
Metalloproteinases ADAM12 and MMP‐14 are associated with cavernous sinus invasion in pituitary adenomas
Wang, Junwen, Voellger, Benjamin, Benzel, Julia, Schlomann, Uwe, Nimsky, Christopher, Bartsch, Jörg W., Carl, Barbara
Published in International journal of cancer (15.09.2016)
Published in International journal of cancer (15.09.2016)
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Journal Article
ADAM8 as a drug target in pancreatic cancer
Schlomann, Uwe, Koller, Garrit, Conrad, Catharina, Ferdous, Taheera, Golfi, Panagiota, Garcia, Adolfo Molejon, Höfling, Sabrina, Parsons, Maddy, Costa, Patricia, Soper, Robin, Bossard, Maud, Hagemann, Thorsten, Roshani, Rozita, Sewald, Norbert, Ketchem, Randal R, Moss, Marcia L, Rasmussen, Fred H, Miller, Miles A, Lauffenburger, Douglas A, Tuveson, David A, Nimsky, Christopher, Bartsch, Jörg W
Published in Nature communications (28.01.2015)
Published in Nature communications (28.01.2015)
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Correlation of MR-Based Metabolomics and Molecular Profiling in the Tumor Microenvironment of Temozolomide-Treated Orthotopic GL261 Glioblastoma in Mice
Zhao, Kai, Calero-Pérez, Pilar, Bopp, Miriam H A, Möschl, Vincent, Pagenstecher, Axel, Mulero-Acevedo, Marta, Vázquez, Mario, Barcia, Carlos, Arús, Carles, Nimsky, Christopher, Rusch, Tillmann, Bartsch, Jörg W, Candiota, Ana Paula
Published in International journal of molecular sciences (18.12.2023)
Published in International journal of molecular sciences (18.12.2023)
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Journal Article
Elevated expression of the metalloproteinase ADAM8 associates with vascular diseases in mice and humans
Schick, Daniel, Babendreyer, Aaron, Wozniak, Justyna, Awan, Tanzeela, Noels, Heidi, Liehn, Elisa, Bartsch, Jörg-W., Vlacil, Ann-Kathrin, Grote, Karsten, Zayat, Rashad, Goetzenich, Andreas, Ludwig, Andreas, Dreymueller, Daniela
Published in Atherosclerosis (01.07.2019)
Published in Atherosclerosis (01.07.2019)
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The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells
Dong, Fangyong, Eibach, Michael, Bartsch, Jörg W, Dolga, Amalia M, Schlomann, Uwe, Conrad, Catharina, Schieber, Susanne, Schilling, Oliver, Biniossek, Martin L, Culmsee, Carsten, Strik, Herwig, Koller, Garrit, Carl, Barbara, Nimsky, Christopher
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2015)
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2015)
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Expression of the Metalloproteinase ADAM8 Is Upregulated in Liver Inflammation Models and Enhances Cytokine Release In Vitro
Awan, Tanzeela, Babendreyer, Aaron, Wozniak, Justyna, Alvi, Abid Mahmood, Sterzer, Viktor, Cook, Lena, Bartsch, Jörg W., Liedtke, Christian, Yildiz, Daniela, Ludwig, Andreas
Published in Mediators of inflammation (11.03.2021)
Published in Mediators of inflammation (11.03.2021)
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MicroRNA let-7b inhibits keratinocyte differentiation by targeting IL-6 mediated ERK signaling in psoriasis
Wu, Yan, Liu, Liu, Bian, Chunxiang, Diao, Qingchun, Nisar, Muhammad Farrukh, Jiang, Xuemei, Bartsch, Jörg W, Zhong, Maojiao, Hu, Xiangyu, Zhong, Julia Li
Published in Cell communication and signaling (15.09.2018)
Published in Cell communication and signaling (15.09.2018)
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The Metalloprotease-Disintegrin ADAM8 Alters the Tumor Suppressor miR-181a-5p Expression Profile in Glioblastoma Thereby Contributing to Its Aggressiveness
Schäfer, Agnes, Evers, Lara, Meier, Lara, Schlomann, Uwe, Bopp, Miriam H A, Dreizner, Gian-Luca, Lassmann, Olivia, Ben Bacha, Aaron, Benescu, Andreea-Cristina, Pojskic, Mirza, Preußer, Christian, von Strandmann, Elke Pogge, Carl, Barbara, Nimsky, Christopher, Bartsch, Jörg W
Published in Frontiers in oncology (15.03.2022)
Published in Frontiers in oncology (15.03.2022)
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The GBM Tumor Microenvironment as a Modulator of Therapy Response: ADAM8 Causes Tumor Infiltration of Tams through HB-EGF/EGFR-Mediated CCL2 Expression and Overcomes TMZ Chemosensitization in Glioblastoma
Liu, Xiaojin, Huang, Yimin, Qi, Yiwei, Wu, Shiqiang, Hu, Feng, Wang, Junwen, Shu, Kai, Zhang, Huaqiu, Bartsch, Jörg W, Nimsky, Christopher, Dong, Fangyong, Lei, Ting
Published in Cancers (01.10.2022)
Published in Cancers (01.10.2022)
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Discovery of Dimeric Arylsulfonamides as Potent ADAM8 Inhibitors
Cuffaro, Doretta, Camodeca, Caterina, Tuccinardi, Tiziano, Ciccone, Lidia, Bartsch, Jörg W, Kellermann, Tanja, Cook, Lena, Nuti, Elisa, Rossello, Armando
Published in ACS medicinal chemistry letters (11.11.2021)
Published in ACS medicinal chemistry letters (11.11.2021)
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Journal Article
ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9
Cook, Lena, Sengelmann, Marie, Winkler, Birte, Nagl, Constanze, Koch, Sarah, Schlomann, Uwe, Slater, Emily P, Miller, Miles A, von Strandmann, Elke Pogge, Dörsam, Bastian, Preußer, Christian, Bartsch, Jörg W
Published in International journal of molecular sciences (10.02.2022)
Published in International journal of molecular sciences (10.02.2022)
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A novel peptide ADAM8 inhibitor attenuates bronchial hyperresponsiveness and Th2 cytokine mediated inflammation of murine asthmatic models
Chen, Jun, Deng, Linhong, Dreymüller, Daniela, Jiang, Xuemei, Long, Jiaoyue, Duan, Yiyuan, Wang, Yue, Luo, Mingzhi, Lin, Feng, Mao, Lizhen, Müller, Bernd, Koller, Garrit, Bartsch, Jörg W
Published in Scientific reports (26.07.2016)
Published in Scientific reports (26.07.2016)
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Proteometabolomics of initial and recurrent glioblastoma highlights an increased immune cell signature with altered lipid metabolism
Cosenza-Contreras, Miguel, Schäfer, Agnes, Sing, Justin, Cook, Lena, Stillger, Maren N, Chen, Chia-Yi, Villacorta Hidalgo, Jose, Pinter, Niko, Meyer, Larissa, Werner, Tilman, Bug, Darleen, Haberl, Zeno, Kübeck, Oliver, Zhao, Kai, Stei, Susanne, Gafencu, Anca Violeta, Ionita, Radu, Brehar, Felix M, Ferrer-Lozano, Jaime, Ribas, Gloria, Cerdá-Alberich, Leo, Martí-Bonmatí, Luis, Nimsky, Christopher, Van Straaten, Alexis, Biniossek, Martin L, Föll, Melanie, Cabezas-Wallscheid, Nina, Büscher, Jörg, Röst, Hannes, Arnoux, Armelle, Bartsch, Jörg W, Schilling, Oliver
Published in Neuro-oncology (Charlottesville, Va.) (04.03.2024)
Published in Neuro-oncology (Charlottesville, Va.) (04.03.2024)
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Journal Article
ADAM9 contributes to vascular invasion in pancreatic ductal adenocarcinoma
Oria, Victor O., Lopatta, Paul, Schmitz, Tatjana, Preca, Bogdan‐Tiberius, Nyström, Alexander, Conrad, Catharina, Bartsch, Jörg W., Kulemann, Birte, Hoeppner, Jens, Maurer, Jochen, Bronsert, Peter, Schilling, Oliver
Published in Molecular oncology (01.02.2019)
Published in Molecular oncology (01.02.2019)
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