Structure-affinity and structure-residence time relationships of macrocyclic Gαq protein inhibitors
Voss, Jan H., Crüsemann, Max, Bartling, Christian R.O., Kehraus, Stefan, Inoue, Asuka, König, Gabriele M., Strømgaard, Kristian, Müller, Christa E.
Published in iScience (21.04.2023)
Published in iScience (21.04.2023)
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Probing the Mint2 Protein–Protein Interaction Network Relevant to the Pathophysiology of Alzheimer's Disease
Jensen, Thomas M. T., Albertsen, Louise, Bartling, Christian R. O., Haugaard‐Kedström, Linda M., Strømgaard, Kristian
Published in Chembiochem : a European journal of chemical biology (04.06.2018)
Published in Chembiochem : a European journal of chemical biology (04.06.2018)
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Site-specific phosphorylation of PSD-95 dynamically regulates the postsynaptic density as observed by phase separation
Vistrup-Parry, Maria, Chen, Xudong, Johansen, Thea L., Bach, Sofie, Buch-Larsen, Sara C., Bartling, Christian R.O., Ma, Chenxue, Clemmensen, Louise S., Nielsen, Michael L., Zhang, Mingjie, Strømgaard, Kristian
Published in iScience (19.11.2021)
Published in iScience (19.11.2021)
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Aryl Fluorosulfate Based Inhibitors That Covalently Target the SIRT5 Lysine Deacylase
Bolding, Julie E., Martín‐Gago, Pablo, Rajabi, Nima, Gamon, Luke F., Hansen, Tobias N., Bartling, Christian R. O., Strømgaard, Kristian, Davies, Michael J., Olsen, Christian A.
Published in Angewandte Chemie International Edition (21.11.2022)
Published in Angewandte Chemie International Edition (21.11.2022)
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Large Libraries of Structurally Diverse Macrocycles Suitable for Membrane Permeation
Nielsen, Alexander L., Bognar, Zsolt, Mothukuri, Ganesh K., Zarda, Anne, Schüttel, Mischa, Merz, Manuel L., Ji, Xinjian, Will, Edward J., Chinellato, Monica, Bartling, Christian R. O., Strømgaard, Kristian, Cendron, Laura, Angelini, Alessandro, Heinis, Christian
Published in Angewandte Chemie International Edition (21.06.2024)
Published in Angewandte Chemie International Edition (21.06.2024)
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Investigation of Carboxylic Acid Isosteres and Prodrugs for Inhibition of the Human SIRT5 Lysine Deacylase Enzyme
Rajabi, Nima, Hansen, Tobias N., Nielsen, Alexander L., Nguyen, Huy T., Bæk, Michael, Bolding, Julie. E., Bahlke, Oskar Ø., Petersen, Sylvester E. G., Bartling, Christian R. O., Strømgaard, Kristian, Olsen, Christian A.
Published in Angewandte Chemie International Edition (23.05.2022)
Published in Angewandte Chemie International Edition (23.05.2022)
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Tight control of the APP-Mint1 interaction in regulating amyloid production
Henry, Shawna M., Kistler, Sabrina A., Lagani, Gavin D., Bartling, Christian R.O., Özcelik, Dennis, Sereikaite, Vita, Strømgaard, Kristian, Beffert, Uwe, Ho, Angela
Published in Brain research (15.10.2023)
Published in Brain research (15.10.2023)
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Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2
Bartling, Christian R. O., Alexopoulou, Flora, Kuschert, Sarah, Chin, Yanni K.-Y., Jia, Xinying, Sereikaite, Vita, Özcelik, Dennis, Jensen, Thomas M., Jain, Palash, Nygaard, Mads M., Harpsøe, Kasper, Gloriam, David E., Mobli, Mehdi, Strømgaard, Kristian
Published in Journal of medicinal chemistry (23.02.2023)
Published in Journal of medicinal chemistry (23.02.2023)
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Targeting the APP-Mint2 Protein–Protein Interaction with a Peptide-Based Inhibitor Reduces Amyloid‑β Formation
Bartling, Christian R. O, Jensen, Thomas M. T, Henry, Shawna M, Colliander, Anna L, Sereikaite, Vita, Wenzler, Marcella, Jain, Palash, Maric, Hans M, Harpsøe, Kasper, Pedersen, Søren W, Clemmensen, Louise S, Haugaard-Kedström, Linda M, Gloriam, David E, Ho, Angela, Strømgaard, Kristian
Published in Journal of the American Chemical Society (20.01.2021)
Published in Journal of the American Chemical Society (20.01.2021)
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Molecular Details of a Coupled Binding and Folding Reaction between the Amyloid Precursor Protein and a Folded Domain
Jensen, Thomas M. T, Bartling, Christian R. O, Karlsson, O. Andreas, Åberg, Emma, Haugaard-Kedström, Linda M, Strømgaard, Kristian, Jemth, Per
Published in ACS chemical biology (16.07.2021)
Published in ACS chemical biology (16.07.2021)
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A high‐affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain
Christensen, Nikolaj R, De Luca, Marta, Lever, Michael B, Richner, Mette, Hansen, Astrid B, Noes‐Holt, Gith, Jensen, Kathrine L, Rathje, Mette, Jensen, Dennis Bo, Erlendsson, Simon, Bartling, Christian RO, Ammendrup‐Johnsen, Ina, Pedersen, Sofie E, Schönauer, Michèle, Nissen, Klaus B, Midtgaard, Søren R, Teilum, Kaare, Arleth, Lise, Sørensen, Andreas T, Bach, Anders, Strømgaard, Kristian, Meehan, Claire F, Vægter, Christian B, Gether, Ulrik, Madsen, Kenneth L
Published in EMBO molecular medicine (08.06.2020)
Published in EMBO molecular medicine (08.06.2020)
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