Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer's disease
Barthélemy, Nicolas R, Horie, Kanta, Sato, Chihiro, Bateman, Randall J
Published in The Journal of experimental medicine (02.11.2020)
Published in The Journal of experimental medicine (02.11.2020)
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Journal Article
Cerebrospinal fluid phospho-tau T217 outperforms T181 as a biomarker for the differential diagnosis of Alzheimer's disease and PET amyloid-positive patient identification
Barthélemy, Nicolas R, Bateman, Randall J, Hirtz, Christophe, Marin, Philippe, Becher, François, Sato, Chihiro, Gabelle, Audrey, Lehmann, Sylvain
Published in Alzheimer's research & therapy (17.03.2020)
Published in Alzheimer's research & therapy (17.03.2020)
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Journal Article
Mitigating the Associations of Kidney Dysfunction With Blood Biomarkers of Alzheimer Disease by Using Phosphorylated Tau to Total Tau Ratios
Janelidze, Shorena, Barthélemy, Nicolas R, He, Yingxin, Bateman, Randall J, Hansson, Oskar
Published in Archives of neurology (Chicago) (01.05.2023)
Published in Archives of neurology (Chicago) (01.05.2023)
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Journal Article
Neurofilaments: neurobiological foundations for biomarker applications
Gafson, Arie R, Barthélemy, Nicolas R, Bomont, Pascale, Carare, Roxana O, Durham, Heather D, Julien, Jean-Pierre, Kuhle, Jens, Leppert, David, Nixon, Ralph A, Weller, Roy O, Zetterberg, Henrik, Matthews, Paul M
Published in Brain (London, England : 1878) (01.07.2020)
Published in Brain (London, England : 1878) (01.07.2020)
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Journal Article
Tau Protein Quantification in Human Cerebrospinal Fluid by Targeted Mass Spectrometry at High Sequence Coverage Provides Insights into Its Primary Structure Heterogeneity
Barthélemy, Nicolas R, Fenaille, François, Hirtz, Christophe, Sergeant, Nicolas, Schraen-Maschke, Susanna, Vialaret, Jérôme, Buée, Luc, Gabelle, Audrey, Junot, Christophe, Lehmann, Sylvain, Becher, François
Published in Journal of proteome research (05.02.2016)
Published in Journal of proteome research (05.02.2016)
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Journal Article
Differential Mass Spectrometry Profiles of Tau Protein in the Cerebrospinal Fluid of Patients with Alzheimer's Disease, Progressive Supranuclear Palsy, and Dementia with Lewy Bodies
Barthélemy, Nicolas R, Gabelle, Audrey, Hirtz, Christophe, Fenaille, François, Sergeant, Nicolas, Schraen-Maschke, Susanna, Vialaret, Jérôme, Buée, Luc, Junot, Christophe, Becher, François, Lehmann, Sylvain
Published in Journal of Alzheimer's disease (12.04.2016)
Published in Journal of Alzheimer's disease (12.04.2016)
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Journal Article
Tau Phosphorylation Rates Measured by Mass Spectrometry Differ in the Intracellular Brain vs. Extracellular Cerebrospinal Fluid Compartments and Are Differentially Affected by Alzheimer's Disease
Barthélemy, Nicolas R, Mallipeddi, Nipun, Moiseyev, Paul, Sato, Chihiro, Bateman, Randall J
Published in Frontiers in aging neuroscience (21.05.2019)
Published in Frontiers in aging neuroscience (21.05.2019)
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Journal Article
Sleep Deprivation Affects Tau Phosphorylation in Human Cerebrospinal Fluid
Barthélemy, Nicolas R., Liu, Haiyan, Lu, William, Kotzbauer, Paul T., Bateman, Randall J., Lucey, Brendan P.
Published in Annals of neurology (01.05.2020)
Published in Annals of neurology (01.05.2020)
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Journal Article
Tau Kinetics in Neurons and the Human Central Nervous System
Sato, Chihiro, Barthélemy, Nicolas R., Mawuenyega, Kwasi G., Patterson, Bruce W., Gordon, Brian A., Jockel-Balsarotti, Jennifer, Sullivan, Melissa, Crisp, Matthew J., Kasten, Tom, Kirmess, Kristopher M., Kanaan, Nicholas M., Yarasheski, Kevin E., Baker-Nigh, Alaina, Benzinger, Tammie L.S., Miller, Timothy M., Karch, Celeste M., Bateman, Randall J.
Published in Neuron (Cambridge, Mass.) (21.03.2018)
Published in Neuron (Cambridge, Mass.) (21.03.2018)
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Journal Article
CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer’s disease
Horie, Kanta, Salvadó, Gemma, Barthélemy, Nicolas R., Janelidze, Shorena, Li, Yan, He, Yingxin, Saef, Benjamin, Chen, Charles D., Jiang, Hong, Strandberg, Olof, Pichet Binette, Alexa, Palmqvist, Sebastian, Sato, Chihiro, Sachdev, Pallavi, Koyama, Akihiko, Gordon, Brian A., Benzinger, Tammie L. S., Holtzman, David M., Morris, John C., Mattsson-Carlgren, Niklas, Stomrud, Erik, Ossenkoppele, Rik, Schindler, Suzanne E., Hansson, Oskar, Bateman, Randall J.
Published in Nature medicine (01.08.2023)
Published in Nature medicine (01.08.2023)
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Journal Article
Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer’s disease
Janelidze, Shorena, Bali, Divya, Ashton, Nicholas J, Barthélemy, Nicolas R, Vanbrabant, Jeroen, Stoops, Erik, Vanmechelen, Eugeen, He, Yingxin, Dolado, Anna Orduña, Triana-Baltzer, Gallen, Pontecorvo, Michael J, Zetterberg, Henrik, Kolb, Hartmuth, Vandijck, Manu, Blennow, Kaj, Bateman, Randall J, Hansson, Oskar
Published in Brain (London, England : 1878) (19.04.2023)
Published in Brain (London, England : 1878) (19.04.2023)
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Journal Article
Highly accurate blood test for Alzheimer’s disease is similar or superior to clinical cerebrospinal fluid tests
Barthélemy, Nicolas R., Salvadó, Gemma, Schindler, Suzanne E., He, Yingxin, Janelidze, Shorena, Collij, Lyduine E., Saef, Benjamin, Henson, Rachel L., Chen, Charles D., Gordon, Brian A., Li, Yan, La Joie, Renaud, Benzinger, Tammie L. S., Morris, John C., Mattsson-Carlgren, Niklas, Palmqvist, Sebastian, Ossenkoppele, Rik, Rabinovici, Gil D., Stomrud, Erik, Bateman, Randall J., Hansson, Oskar
Published in Nature medicine (01.04.2024)
Published in Nature medicine (01.04.2024)
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Journal Article
Acute sleep loss decreases CSF‐to‐blood clearance of Alzheimer's disease biomarkers
Liu, Haiyan, Barthélemy, Nicolas R., Ovod, Vitaliy, Bollinger, James G., He, Yingxin, Chahin, Samir L., Androff, Brendan, Bateman, Randall J., Lucey, Brendan P.
Published in Alzheimer's & dementia (01.07.2023)
Published in Alzheimer's & dementia (01.07.2023)
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Journal Article
CSF tau microtubule-binding region identifies pathological changes in primary tauopathies
Horie, Kanta, Barthélemy, Nicolas R., Spina, Salvatore, VandeVrede, Lawren, He, Yingxin, Paterson, Ross W., Wright, Brenton A., Day, Gregory S., Davis, Albert A., Karch, Celeste M., Seeley, William W., Perrin, Richard J., Koppisetti, Rama K., Shaikh, Faris, Lago, Argentina Lario, Heuer, Hilary W., Ghoshal, Nupur, Gabelle, Audrey, Miller, Bruce L., Boxer, Adam L., Bateman, Randall J., Sato, Chihiro
Published in Nature medicine (01.12.2022)
Published in Nature medicine (01.12.2022)
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Journal Article
Suvorexant Acutely Decreases Tau Phosphorylation and Aβ in the Human CNS
Lucey, Brendan P., Liu, Haiyan, Toedebusch, Cristina D., Freund, David, Redrick, Tiara, Chahin, Samir L., Mawuenyega, Kwasi G., Bollinger, James G., Ovod, Vitaliy, Barthélemy, Nicolas R., Bateman, Randall J.
Published in Annals of neurology (01.07.2023)
Published in Annals of neurology (01.07.2023)
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Journal Article
A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease
Barthélemy, Nicolas R., Li, Yan, Joseph-Mathurin, Nelly, Gordon, Brian A., Hassenstab, Jason, Benzinger, Tammie. L. S., Buckles, Virginia, Fagan, Anne M., Perrin, Richard J., Goate, Alison M., Morris, John C., Karch, Celeste M., Xiong, Chengjie, Allegri, Ricardo, Mendez, Patricio Chrem, Berman, Sarah B., Ikeuchi, Takeshi, Mori, Hiroshi, Shimada, Hiroyuki, Shoji, Mikio, Suzuki, Kazushi, Noble, James, Farlow, Martin, Chhatwal, Jasmeer, Graff-Radford, Neill R., Salloway, Stephen, Schofield, Peter R., Masters, Colin L., Martins, Ralph N., O’Connor, Antoinette, Fox, Nick C., Levin, Johannes, Jucker, Mathias, Gabelle, Audrey, Lehmann, Sylvain, Sato, Chihiro, Bateman, Randall J., McDade, Eric
Published in Nature Medicine (01.03.2020)
Published in Nature Medicine (01.03.2020)
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Magazine Article
Timing of Biomarker Changes in Sporadic Alzheimer's Disease in Estimated Years from Symptom Onset
Li, Yan, Yen, Daniel, Hendrix, Rachel D, Gordon, Brian A, Dlamini, Sibonginkhosi, Barthélemy, Nicolas R, Aschenbrenner, Andrew J, Henson, Rachel L, Herries, Elizabeth M, Volluz, Katherine, Kirmess, Kristopher, Eastwood, Stephanie, Meyer, Matthew, Heller, Maren, Jarrett, Lea, McDade, Eric, Holtzman, David M, Benzinger, Tammie L S, Morris, John C, Bateman, Randall J, Xiong, Chengjie, Schindler, Suzanne E
Published in Annals of neurology (01.05.2024)
Published in Annals of neurology (01.05.2024)
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Journal Article
Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons
Capano, Lucia S, Sato, Chihiro, Ficulle, Elena, Yu, Anan, Horie, Kanta, Kwon, Ji-Sun, Burbach, Kyle F, Barthélemy, Nicolas R, Fox, Susan G, Karch, Celeste M, Bateman, Randall J, Houlden, Henry, Morimoto, Richard I, Holtzman, David M, Duff, Karen E, Yoo, Andrew S
Published in Cell stem cell (02.06.2022)
Published in Cell stem cell (02.06.2022)
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