Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer
Lee, Min-Sik, Dennis, Courtney, Naqvi, Insia, Dailey, Lucas, Lorzadeh, Alireza, Ye, George, Zaytouni, Tamara, Adler, Ashley, Hitchcock, Daniel S, Lin, Lin, Hoffman, Megan T, Bhuiyan, Aladdin M, Barth, Jaimie L, Machacek, Miranda E, Mino-Kenudson, Mari, Dougan, Stephanie K, Jadhav, Unmesh, Clish, Clary B, Kalaany, Nada Y
Published in Nature (London) (13.04.2023)
Published in Nature (London) (13.04.2023)
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Journal Article
Therapeutic avenues for cancer neuroscience: translational frontiers and clinical opportunities
Shi, Diana D, Guo, Jimmy A, Hoffman, Hannah I, Su, Jennifer, Mino-Kenudson, Mari, Barth, Jaimie L, Schenkel, Jason M, Loeffler, Jay S, Shih, Helen A, Hong, Theodore S, Wo, Jennifer Y, Aguirre, Andrew J, Jacks, Tyler, Zheng, Lei, Wen, Patrick Y, Wang, Timothy C, Hwang, William L
Published in The lancet oncology (01.02.2022)
Published in The lancet oncology (01.02.2022)
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Journal Article
Lymphocyte-activation gene 3 in non-small-cell lung carcinomas: correlations with clinicopathologic features and prognostic significance
Shepherd, Daniel J, Tabb, Elisabeth S, Kunitoki, Keiko, Zhang, M Lisa, Kem, Marina, Barth, Jaimie, Qualls, David A, Mooradian, Meghan J, Gainor, Justin F, Mino-Kenudson, Mari, Hung, Yin P
Published in Modern pathology (01.05.2022)
Published in Modern pathology (01.05.2022)
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Journal Article
Concordance of ASCL1, NEUROD1 and POU2F3 transcription factor‐based subtype assignment in paired tumour samples from small cell lung carcinoma
Denize, Thomas, Meador, Catherine B, Rider, Anna B, Ganci, Maria L, Barth, Jaimie L, Kem, Marina, Mino‐Kenudson, Mari, Hung, Yin P
Published in Histopathology (01.12.2023)
Published in Histopathology (01.12.2023)
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Journal Article
Human lung cancer harbors spatially organized stem-immunity hubs associated with response to immunotherapy
Chen, Jonathan H, Nieman, Linda T, Spurrell, Maxwell, Jorgji, Vjola, Elmelech, Liad, Richieri, Peter, Xu, Katherine H, Madhu, Roopa, Parikh, Milan, Zamora, Izabella, Mehta, Arnav, Nabel, Christopher S, Freeman, Samuel S, Pirl, Joshua D, Lu, Chenyue, Meador, Catherine B, Barth, Jaimie L, Sakhi, Mustafa, Tang, Alexander L, Sarkizova, Siranush, Price, Colles, Fernandez, Nicolas F, Emanuel, George, He, Jiang, Van Raay, Katrina, Reeves, Jason W, Yizhak, Keren, Hofree, Matan, Shih, Angela, Sade-Feldman, Moshe, Boland, Genevieve M, Pelka, Karin, Aryee, Martin J, Mino-Kenudson, Mari, Gainor, Justin F, Korsunsky, Ilya, Hacohen, Nir
Published in Nature immunology (01.04.2024)
Published in Nature immunology (01.04.2024)
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Journal Article
Vasculopathy and Increased Vascular Congestion in Fatal COVID-19 and Acute Respiratory Distress Syndrome
Villalba, Julian A, Hilburn, Caroline F, Garlin, Michelle A, Elliott, Grant A, Li, Yijia, Kunitoki, Keiko, Poli, Sergio, Alba, George A, Madrigal, Emilio, Taso, Manuel, Price, Melissa C, Aviles, Alexis J, Araujo-Medina, Milagros, Bonanno, Liana, Boyraz, Baris, Champion, Samantha N, Harris, Cynthia K, Helland, Timothy L, Hutchison, Bailey, Jobbagy, Soma, Marshall, Michael S, Shepherd, Daniel J, Barth, Jaimie L, Hung, Yin P, Ly, Amy, Hariri, Lida P, Turbett, Sarah E, Pierce, Virginia M, Branda, John A, Rosenberg, Eric S, Mendez-Pena, Javier, Chebib, Ivan, Rosales, Ivy A, Smith, Rex N, Miller, Miles A, Rosas, Ivan O, Hardin, Charles C, Baden, Lindsey R, Medoff, Benjamin D, Colvin, Robert B, Little, Brent P, Stone, James R, Mino-Kenudson, Mari, Shih, Angela R
Published in American journal of respiratory and critical care medicine (01.10.2022)
Published in American journal of respiratory and critical care medicine (01.10.2022)
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Journal Article
Analysis of lorlatinib analogs reveals a roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer
Shiba-Ishii, Aya, Johnson, Ted W, Dagogo-Jack, Ibiayi, Mino-Kenudson, Mari, Johnson, Theodore R, Wei, Ping, Weinrich, Scott L, McTigue, Michele A, Walcott, Makeba A, Nguyen-Phuong, Linh, Dionne, Kristin, Acker, Adam, Kiedrowski, Lesli A, Do, Andrew, Peterson, Jennifer L, Barth, Jaimie L, Yeap, Beow Y, Gainor, Justin F, Lin, Jessica J, Yoda, Satoshi, Hata, Aaron N
Published in Nature cancer (01.06.2022)
Published in Nature cancer (01.06.2022)
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Journal Article
Immune Responses in Checkpoint Myocarditis Across Heart, Blood, and Tumor
Blum, Steven M, Zlotoff, Daniel A, Smith, Neal P, Kernin, Isabela J, Ramesh, Swetha, Zubiri, Leyre, Caplin, Joshua, Samanta, Nandini, Martin, Sidney C, Tirard, Alice, Sen, Pritha, Song, Yuhui, Barth, Jaimie, Slowikowski, Kamil, Nasrallah, Mazen, Tantivit, Jessica, Manakongtreecheep, Kasidet, Arnold, Benjamin Y, McGuire, John, Pinto, Christopher J, McLoughlin, Daniel, Jackson, Monica, Chan, PuiYee, Lawless, Aleigha, Sharova, Tatyana, Nieman, Linda T, Gainor, Justin F, Juric, Dejan, Mino-Kenudsen, Mari, Sullivan, Ryan J, Boland, Genevieve M, Stone, James R, Thomas, Molly F, Neilan, Tomas G, Reynolds, Kerry L, Villani, Alexandra-Chloé
Published in bioRxiv (29.11.2023)
Published in bioRxiv (29.11.2023)
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Paper
Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment
Hwang, William L, Jagadeesh, Karthik A, Guo, Jimmy A, Hoffman, Hannah I, Yadollahpour, Payman, Reeves, Jason W, Mohan, Rahul, Drokhlyansky, Eugene, Van Wittenberghe, Nicholas, Ashenberg, Orr, Farhi, Samouil L, Schapiro, Denis, Divakar, Prajan, Miller, Eric, Zollinger, Daniel R, Eng, George, Schenkel, Jason M, Su, Jennifer, Shiau, Carina, Yu, Patrick, Freed-Pastor, William A, Abbondanza, Domenic, Mehta, Arnav, Gould, Joshua, Lambden, Conner, Porter, Caroline B M, Tsankov, Alexander, Dionne, Danielle, Waldman, Julia, Cuoco, Michael S, Nguyen, Lan, Delorey, Toni, Phillips, Devan, Barth, Jaimie L, Kem, Marina, Rodrigues, Clifton, Ciprani, Debora, Roldan, Jorge, Zelga, Piotr, Jorgji, Vjola, Chen, Jonathan H, Ely, Zackery, Zhao, Daniel, Fuhrman, Kit, Fropf, Robin, Beechem, Joseph M, Loeffler, Jay S, Ryan, David P, Weekes, Colin D, Ferrone, Cristina R, Qadan, Motaz, Aryee, Martin J, Jain, Rakesh K, Neuberg, Donna S, Wo, Jennifer Y, Hong, Theodore S, Xavier, Ramnik, Aguirre, Andrew J, Rozenblatt-Rosen, Orit, Mino-Kenudson, Mari, Castillo, Carlos Fernandez-Del, Liss, Andrew S, Ting, David T, Jacks, Tyler, Regev, Aviv
Published in Nature genetics (01.08.2022)
Published in Nature genetics (01.08.2022)
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Journal Article
The use of cryoablation to overcome resistance to PD-1 blockade in unresectable melanoma
Mooradian, Meghan, Fintelmann, Florian J., Kaufman, Howard E., Mino-Kenudson, Mari, Barth, Jaimie Lynn, Lawless, Aleigha, Sharova, Tatyana, Fadden, Riley, Rubin, Krista M., Lawrence, Donald P., Frederick, Dennie T., Sade-Feldman, Moshe, Sullivan, Ryan J.
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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Journal Article
Abstract 11983: Associations Between Circulating Proteins and Intracardiac Immune Populations in Immune Checkpoint Inhibitor-Associated Myocarditis
Zlotoff, Daniel, Blum, Steven, Ramesh, Swetha, Kernin, Isabela, Smith, Neal, Sen, Pritha, Zubiri, Leyre, Tirard, Alice, Nasrallah, Mazen, Tantivit, Jessica, Manakongtreecheep, Kasidet, Arnold, Benjamin, Chan, PuiYee, Barth, Jaimie, Juric, Dejan, Sullivan, Ryan, Boland, Genevieve, Mino-Kenudson, Mari, Stone, James R, Thomas, Molly F, Caplin, Joshua, Reynolds, Kerry, Neilan, Tomas G, Villani, Alexandra-Chloe
Published in Circulation (New York, N.Y.) (08.11.2022)
Published in Circulation (New York, N.Y.) (08.11.2022)
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Journal Article
Single-cell profiling of human heart and blood in immune checkpoint inhibitor-associated myocarditis
Blum, Steven Michael, Zlotoff, Daniel A., Smith, Neal, Ramesh, Swetha, Kernin, Isabela, Sen, Pritha, Zubiri, Leyre, Tirard, Alice, Nasrallah, Mazen, Tantivit, Jessica, Barth, Jaimie Lynn, Juric, Dejan, Sullivan, Ryan J., Boland, Genevieve Marie, Mino-Kenudson, Mari, Stone, James, Thomas, Molly, Reynolds, Kerry Lynn, Neilan, Tomas G., Villani, Alexandra-Chloé
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Journal Article
Spatially defined enrichment of a neuronal-like malignant phenotype in pancreatic cancer after neoadjuvant treatment
Hwang, William L., Jagadeesh, Karthik, Guo, Jimmy, Hoffman, Hannah I., Yadollahpour, Payman, Reeves, Jason, Divakar, Prajan, Delorey, Toni, Mehta, Arnav, Barth, Jaimie Lynn, Zelga, Piotr, Hong, Theodore S., Jain, Rakesh K., Aguirre, Andrew, Fernandez Del-Castillo, Carlos, Mino-Kenudson, Mari, Liss, Andrew, Ting, David Tsai, Regev, Aviv, Jacks, Tyler
Published in Journal of clinical oncology (01.02.2022)
Published in Journal of clinical oncology (01.02.2022)
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Journal Article
Abstract 94: Multi-compartment reprogramming and spatially-resolved interactions in frozen pancreatic cancer with and without neoadjuvant chemotherapy and radiotherapy at single-cell resolution
Hwang, William L., Jagadeesh, Karthik A., Guo, Jimmy A., Hoffman, Hannah I., Yadollahpour, Payman, Reeves, Jason, Drokhlyansky, Eugene, Van Wittenberghe, Nicholas, Farhi, Samouil, Schapiro, Denis, Eng, George, Schenkel, Jason M., Freed-Pastor, William A., Ashenberg, Orr, Rodrigues, Clifton, Abbondanza, Domenic, Delorey, Toni, Phillips, Devan, Roldan, Jorge, Ciprani, Debora, Kern, Marina, Barth, Jaimie L., Zollinger, Daniel R., Fuhrman, Kit, Fropf, Robin, Beechem, Joseph, Weekes, Colin, Ferrone, Cristina R., Wo, Jennifer Y., Hong, Theodore S., Rozenblatt-Rosen, Orit, Aguirre, Andrew J., Mino-Kenudson, Mari, Fernandez-del- Castillo, Carlos, Liss, Andrew S., Ting, David T., Jacks, Tyler, Regev, Aviv
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract 2513: Distinct cancer-intrinsic mechanisms mediate nerve recruitment/outgrowth versus perineural invasion
Hwang, William L., Su, Jennifer, Shiau, Carina, Wang, Peter L., Guo, Jimmy A., Lester, Nicole A., Barth, Jaimie L., Hoffman, Hannah I., Divakar, Prajan, Reeves, Jason W., Miller, Eric, Beechem, Joseph M., Aguirre, Andrew J., Zheng, Lei, Ting, David T., Mino-Kenudson, Mari, Jacks, Tyler
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract 771: Mechanisms of genetic predisposition to multifocal lung cancer
Burr, Risa, Leshchiner, Ignaty, Costantino, Christina L., Blohmer, Martin, Sundaresan, Tilak, Cha, Justin, Seeger, Karsen, Guay, Sara, Danysh, Brian P., Gore, Ira, Jacobs, Raquel A., Slowik, Kara, Utro, Filippo, Rhrissorrakrai, Kahn, Levovitz, Chaya, Barth, Jaimie L., Dubash, Taronish, Chirn, Brian, Parida, Laxmi, Sequist, Lecia V., Mino-Kenudson, Mari, Naxerova, Kamila, Maheswaran, Shyamala, Getz, Gad, Haber, Daniel A.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract 7474: T-cell responses across heart, blood, and tumor in patients with immune checkpoint inhibitor-related myocarditis (irMyocarditis)
Blum, Steven, Zlotoff, Daniel A., Smith, Neal P., Kernin, Isabela J., Ramesh, Swetha, Oliveira, Giacomo, Zubiri, Leyre, Caplin, Joshua, Samanta, Nandini, Martin, Sidney, Wang, Mike, Tirard, Alice, Sen, Pritha, Song, Yuhui, Xu, Katherine, Barth, Jaimie L., Slowikowski, Kamil, Nasrallah, Mazen, Tantivit, Jessica, Manakongtreecheep, Kasidet, Arnold, Benjamin Y., McGuire, John, Afeyan, Alexander B., Pinto, Christopher J., McLoughlin, Daniel, Jackson, Monica, Chan, PuiYee, Lawless, Aleigha, Michaud, William A., Sharova, Tatyana, Nieman, Linda T., Gainor, Justin F., Juric, Dejan, Mino-Kenudsen, Mari, Sullivn, Ryan J., Boland, Genevieve M., Stone, James R., Wu, Catherine J., Thomas, Molly F., Neilan, Tomas G., Reynolds, Kerry L., Villani, Alexandra-Chloé
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Abstract C052: Identifying mediators of perineural invasion in pancreatic cancer using spatial transcriptomics
Hwang, William L., Su, Jennifer, Guo, Jimmy A., Shiau, Carina, Barth, Jaimie L., Hoffman, Hannah I., Divakar, Prajan, Reeves, Jason W., Miller, Eric, Cervantes-Jaramillo, Grissel, Freed-Pastor, William, Funes, Vanessa, Wo, Jennifer Y., Hong, Theodore S., Castillo, Carlos Fernandez-del, Zheng, Lei, Aguirre, Andrew J., Ting, David T., Mino-Kenudson, Mari, Jacks, Tyler
Published in Cancer research (Chicago, Ill.) (15.11.2022)
Published in Cancer research (Chicago, Ill.) (15.11.2022)
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Journal Article
Abstract SY12-04: Multicellular spatial community featuring a novel neuronal-like malignant phenotype is enriched in pancreatic cancer after neoadjuvant chemotherapy and radiotherapy
Hwang, William L., Jagadeesh, Karthik A., Guo, Jimmy A., Hoffman, Hannah I., Shiau, Carina, Su, Jennifer, Yadollahpour, Payman, Reeves, Jason W., Kim, Youngmi, Kim, Sean, Gregory, Mark, Divakar, Prajan, Miller, Eric, Rhodes, Michael, Warren, Sarah, Rueckert, Erroll, Fuhrman, Kit, Zollinger, Daniel R., Fropf, Robin, Beechem, Joseph M., Mehta, Arnav, Delorey, Toni, McCabe, Cristin, Barth, Jaimie L., Zelga, Piotr, Ferrone, Cristina R., Qadan, Motaz, Lillemoe, Keith D., Jain, Rakesh K., Wo, Jennifer Y., Hong, Theodore S., Xavier, Ramnik, Rozenblatt-Rosen, Orit, Aguirre, Andrew J., Castillo, Carlos Fernandez-Del, Liss, Andrew S., Mino-Kenudson, Mari, Ting, David T., Jacks, Tyler, Regev, Aviv
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Germline mutations and developmental mosaicism underlying EGFR -mutant lung cancer
Burr, Risa, Leshchiner, Ignaty, Costantino, Christina L, Blohmer, Martin, Sundaresan, Tilak, Cha, Justin, Seeger, Karsen, Guay, Sara, Danysh, Brian P, Gore, Ira, Jacobs, Raquel A, Slowik, Kara, Utro, Filippo, Rhrissorrakrai, Kahn, Levovitz, Chaya, Barth, Jaimie L, Dubash, Taronish, Chirn, Brian, Parida, Laxmi, Sequist, Lecia V, Lennerz, Jochen K, Mino-Kenudson, Mari, Maheswaran, Shyamala, Naxerova, Kamila, Getz, Gad, Haber, Daniel A
Published in medRxiv : the preprint server for health sciences (29.09.2023)
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Published in medRxiv : the preprint server for health sciences (29.09.2023)
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