Genome mining of biosynthetic and chemotherapeutic gene clusters in Streptomyces bacteria
Belknap, Kaitlyn C, Park, Cooper J, Barth, Brian M, Andam, Cheryl P
Published in Scientific reports (06.02.2020)
Published in Scientific reports (06.02.2020)
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Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin
Scherer, Philipp E, Holland, William L, Miller, Russell A, Wang, Zhao V, Sun, Kai, Barth, Brian M, Bui, Hai H, Davis, Kathryn E, Bikman, Benjamin T, Halberg, Nils, Rutkowski, Joseph M, Wade, Mark R, Tenorio, Vincent M, Kuo, Ming-Shang, Brozinick, Joseph T, Zhang, Bei B, Birnbaum, Morris J, Summers, Scott A
Published in Nature medicine (01.01.2011)
Published in Nature medicine (01.01.2011)
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Near-Infrared Emitting Fluorophore-Doped Calcium Phosphate Nanoparticles for In Vivo Imaging of Human Breast Cancer
Altınoǧlu, Erhan I˙, Russin, Timothy J, Kaiser, James M, Barth, Brian M, Eklund, Peter C, Kester, Mark, Adair, James H
Published in ACS nano (28.10.2008)
Published in ACS nano (28.10.2008)
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Ceramide-based therapeutics for the treatment of cancer
Barth, Brian M, Cabot, Myles C, Kester, Mark
Published in Anti-cancer agents in medicinal chemistry (01.11.2011)
Published in Anti-cancer agents in medicinal chemistry (01.11.2011)
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Targeted Indocyanine-Green-Loaded Calcium Phosphosilicate Nanoparticles for In Vivo Photodynamic Therapy of Leukemia
Barth, Brian M, I. Altinoğlu, Erhan, Shanmugavelandy, Sriram S, Kaiser, James M, Crespo-Gonzalez, Daniza, DiVittore, Nicole A, McGovern, Christopher, Goff, Trevor M, Keasey, Nicole R, Adair, James H, Loughran, Thomas P, Claxton, David F, Kester, Mark
Published in ACS nano (26.07.2011)
Published in ACS nano (26.07.2011)
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Ceramide 1-Phosphate Mediates Endothelial Cell Invasion via the Annexin a2-p11 Heterotetrameric Protein Complex
Hankins, Jody L., Ward, Katherine E., Linton, Sam S., Barth, Brian M., Stahelin, Robert V., Fox, Todd E., Kester, Mark
Published in The Journal of biological chemistry (05.07.2013)
Published in The Journal of biological chemistry (05.07.2013)
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Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia—Impact on enzyme activity and response to cytotoxics
Morad, Samy A.F., Tan, Su-Fern, Feith, David J., Kester, Mark, Claxton, David F., Loughran, Thomas P., Barth, Brian M., Fox, Todd E., Cabot, Myles C.
Published in Biochimica et biophysica acta (01.07.2015)
Published in Biochimica et biophysica acta (01.07.2015)
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Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer
Jiang, Yixing, DiVittore, Nicole A., Kaiser, James M., Shanmugavelandy, Sriram S., Fritz, Jennifer L., Heakal, Yasser, Tagaram, Hephzibah Rani S., Cheng, Hua, Cabot, Myles C., Staveley-O'Carroll, Kevin F., Tran, Melissa A., Fox, Todd E., Barth, Brian M., Kester, Mark
Published in Cancer biology & therapy (01.10.2011)
Published in Cancer biology & therapy (01.10.2011)
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Journal Article
Metabolism of short-chain ceramide by human cancer cells—Implications for therapeutic approaches
Chapman, Jacqueline V., Gouazé-Andersson, Valérie, Messner, Maria C., Flowers, Margaret, Karimi, Ramin, Kester, Mark, Barth, Brian M., Liu, Xin, Liu, Yong-Yu, Giuliano, Armando E., Cabot, Myles C.
Published in Biochemical pharmacology (01.08.2010)
Published in Biochemical pharmacology (01.08.2010)
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Acid ceramidase is upregulated in AML and represents a novel therapeutic target
Tan, Su-Fern, Liu, Xin, Fox, Todd E., Barth, Brian M., Sharma, Arati, Turner, Stephen D., Awwad, Andy, Dewey, Alden, Doi, Kenichiro, Spitzer, Barbara, Shah, Mithun Vinod, Morad, Samy A.F., Desai, Dhimant, Amin, Shantu, Zhu, Junjia, Liao, Jason, Yun, Jong, Kester, Mark, Claxton, David F., Wang, Hong-Gang, Cabot, Myles C., Schuchman, Edward H., Levine, Ross L., Feith, David J., Loughran, Thomas P.
Published in Oncotarget (13.12.2016)
Published in Oncotarget (13.12.2016)
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Extracts of Devil's Club (Oplopanax horridus) Exert Therapeutic Efficacy in Experimental Models of Acute Myeloid Leukemia
McGill, Colin M, Alba‐Rodriguez, Estefania J, Li, Shuo, Benson, Charles J, Ondrasik, Regina M, Fisher, Lindsey N, Claxton, David F, Barth, Brian M
Published in Phytotherapy research (01.09.2014)
Published in Phytotherapy research (01.09.2014)
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Journal Article
Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia1
Morad, Samy A.F., Ryan, Terence E., Neufer, P. Darrell, Zeczycki, Tonya N., Davis, Traci S., MacDougall, Matthew R., Fox, Todd E., Tan, Su-Fern, Feith, David J., Loughran, Thomas P., Kester, Mark, Claxton, David F., Barth, Brian M., Deering, Tye G., Cabot, Myles C.
Published in Journal of lipid research (01.07.2016)
Published in Journal of lipid research (01.07.2016)
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Inhibition of NADPH oxidase by glucosylceramide confers chemoresistance
Barth, Brian M., Gustafson, Sally J., Young, Megan M., Fox, Todd E., Shanmugavelandy, Sriram S., Kaiser, James M., Cabot, Myles C., Kester, Mark, Kuhn, Thomas B.
Published in Cancer biology & therapy (01.12.2010)
Published in Cancer biology & therapy (01.12.2010)
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Journal Article
Sphingolipids as Regulators of Neuro-Inflammation and NADPH Oxidase 2
Arsenault, Emma J., McGill, Colin M., Barth, Brian M.
Published in Neuromolecular medicine (01.03.2021)
Published in Neuromolecular medicine (01.03.2021)
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Journal Article
Bioconjugation of Calcium Phosphosilicate Composite Nanoparticles for Selective Targeting of Human Breast and Pancreatic Cancers In Vivo
Barth, Brian M, Sharma, Rahul, Altınoǧlu, Erhan İ, Morgan, Thomas T, Shanmugavelandy, Sriram S, Kaiser, James M, McGovern, Christopher, Matters, Gail L, Smith, Jill P, Kester, Mark, Adair, James H
Published in ACS nano (23.03.2010)
Published in ACS nano (23.03.2010)
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Journal Article
Nanoliposomal ceramide prevents in vivo growth of hepatocellular carcinoma
Tagaram, Hephzibah Rani S, DiVittore, Nicole A, Barth, Brian M, Kaiser, James M, Avella, Diego, Kimchi, Eric T, Jiang, Yixing, Isom, Harriet C, Kester, Mark, Staveley-O'Carroll, Kevin F
Published in Gut (01.05.2011)
Published in Gut (01.05.2011)
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Maritoclax induces apoptosis in acute myeloid leukemia cells with elevated Mcl-1 expression
Doi, Kenichiro, Liu, Qiang, Gowda, Krishne, Barth, Brian M, Claxton, David, Amin, Shantu, Loughran Jr, Thomas P, Wang, Hong-Gang
Published in Cancer biology & therapy (01.08.2014)
Published in Cancer biology & therapy (01.08.2014)
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