A Survey of the Role of Noncovalent Sulfur Interactions in Drug Design
Beno, Brett R, Yeung, Kap-Sun, Bartberger, Michael D, Pennington, Lewis D, Meanwell, Nicholas A
Published in Journal of medicinal chemistry (11.06.2015)
Published in Journal of medicinal chemistry (11.06.2015)
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Journal Article
Ir-Catalyzed Asymmetric Allylic Alkylation of Dialkyl Malonates Enabling the Construction of Enantioenriched All-Carbon Quaternary Centers
Moghadam, Farbod A., Hicks, Elliot F., Sercel, Zachary P., Cusumano, Alexander Q., Bartberger, Michael D., Stoltz, Brian M.
Published in Journal of the American Chemical Society (11.05.2022)
Published in Journal of the American Chemical Society (11.05.2022)
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Journal Article
Enantioselective synthesis of highly oxygenated acyclic quaternary center-containing building blocks via palladium-catalyzed decarboxylative allylic alkylation of cyclic siloxyketones
Ngamnithiporn, Aurapat, Iwayama, Toshihiko, Bartberger, Michael D., Stoltz, Brian M.
Published in Chemical science (Cambridge) (15.09.2020)
Published in Chemical science (Cambridge) (15.09.2020)
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Journal Article
Systematic Study of the Glutathione (GSH) Reactivity of N‑Arylacrylamides: 1. Effects of Aryl Substitution
Cee, Victor J, Volak, Laurie P, Chen, Yuping, Bartberger, Michael D, Tegley, Chris, Arvedson, Tara, McCarter, John, Tasker, Andrew S, Fotsch, Christopher
Published in Journal of medicinal chemistry (10.12.2015)
Published in Journal of medicinal chemistry (10.12.2015)
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Journal Article
Systematic Study of the Glutathione Reactivity of N‑Phenylacrylamides: 2. Effects of Acrylamide Substitution
Birkholz, Adam, Kopecky, David J, Volak, Laurie P, Bartberger, Michael D, Chen, Yuping, Tegley, Christopher M, Arvedson, Tara, McCarter, John D, Fotsch, Christopher, Cee, Victor J
Published in Journal of medicinal chemistry (22.10.2020)
Published in Journal of medicinal chemistry (22.10.2020)
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Journal Article
The chemical biology of HNO signaling
Bianco, Christopher L., Toscano, John P., Bartberger, Michael D., Fukuto, Jon M.
Published in Archives of biochemistry and biophysics (01.03.2017)
Published in Archives of biochemistry and biophysics (01.03.2017)
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Journal Article
Enantioselective total synthesis of (−)-myrifabral A and B
Fulton, Tyler J, Chen, Anthony Y, Bartberger, Michael D, Stoltz, Brian M
Published in Chemical science (Cambridge) (21.10.2020)
Published in Chemical science (Cambridge) (21.10.2020)
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Journal Article
Anion−Aromatic Bonding: A Case for Anion Recognition by π-Acidic Rings
Mascal, Mark, Armstrong, Alan, Bartberger, Michael D
Published in Journal of the American Chemical Society (05.06.2002)
Published in Journal of the American Chemical Society (05.06.2002)
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Journal Article
Divergent Catalysis: Catalytic Asymmetric [4+2] Cycloaddition of Palladium Enolates
Flesch, Kaylin N., Cusumano, Alexander Q., Chen, Peng-Jui, Strong, Christian Santiago, Sardini, Stephen R., Du, Yun E., Bartberger, Michael D., Goddard, William A., Stoltz, Brian M.
Published in Journal of the American Chemical Society (24.05.2023)
Published in Journal of the American Chemical Society (24.05.2023)
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Journal Article
Discovery of AM-6494: A Potent and Orally Efficacious β‑Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor with in Vivo Selectivity over BACE2
Pettus, Liping H, Bourbeau, Matthew P, Bradley, Jodi, Bartberger, Michael D, Chen, Kui, Hickman, Dean, Johnson, Michael, Liu, Qingyian, Manning, James R, Nanez, Adrian, Siegmund, Aaron C, Wen, Paul H, Whittington, Douglas A, Allen, Jennifer R, Wood, Stephen
Published in Journal of medicinal chemistry (12.03.2020)
Published in Journal of medicinal chemistry (12.03.2020)
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Journal Article
Discovery of TRPM8 Antagonist (S)‑6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of Migraine
Horne, Daniel B, Biswas, Kaustav, Brown, James, Bartberger, Michael D, Clarine, Jeffrey, Davis, Carl D, Gore, Vijay K, Harried, Scott, Horner, Michelle, Kaller, Matthew R, Lehto, Sonya G, Liu, Qingyian, Ma, Vu V, Monenschein, Holger, Nguyen, Thomas T, Yuan, Chester C, Youngblood, Beth D, Zhang, Maosheng, Zhong, Wenge, Allen, Jennifer R, Chen, Jian Jeffrey, Gavva, Narender R
Published in Journal of medicinal chemistry (27.09.2018)
Published in Journal of medicinal chemistry (27.09.2018)
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Journal Article
Iridium-Catalyzed Enantioselective and Diastereoselective Hydrogenation of 1,3-Disubstituted Isoquinolines
Kim, Alexia N, Ngamnithiporn, Aurapat, Welin, Eric R, Daiger, Martin T, Grünanger, Christian U, Bartberger, Michael D, Virgil, Scott C, Stoltz, Brian M
Published in ACS catalysis (06.03.2020)
Published in ACS catalysis (06.03.2020)
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Journal Article
Mechanistic Insights into the Racemization of Fused Cyclopropyl Isoxazolines
Quasdorf, Kyle W, Birkholz, Adam B, Bartberger, Michael D, Colyer, John, Osgood, Stephen, Crossley, Kevin, Caille, Seb
Published in Organic letters (20.03.2020)
Published in Organic letters (20.03.2020)
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Journal Article
Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction
Rew, Yosup, Sun, Daqing, Gonzalez-Lopez De Turiso, Felix, Bartberger, Michael D, Beck, Hilary P, Canon, Jude, Chen, Ada, Chow, David, Deignan, Jeffrey, Fox, Brian M, Gustin, Darin, Huang, Xin, Jiang, Min, Jiao, Xianyun, Jin, Lixia, Kayser, Frank, Kopecky, David J, Li, Yihong, Lo, Mei-Chu, Long, Alexander M, Michelsen, Klaus, Oliner, Jonathan D, Osgood, Tao, Ragains, Mark, Saiki, Anne Y, Schneider, Steve, Toteva, Maria, Yakowec, Peter, Yan, Xuelei, Ye, Qiuping, Yu, Dongyin, Zhao, Xiaoning, Zhou, Jing, Medina, Julio C, Olson, Steven H
Published in Journal of medicinal chemistry (14.06.2012)
Published in Journal of medicinal chemistry (14.06.2012)
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Journal Article
Fragment-Linking Approach Using (19)F NMR Spectroscopy To Obtain Highly Potent and Selective Inhibitors of β-Secretase
Jordan, John B, Whittington, Douglas A, Bartberger, Michael D, Sickmier, E Allen, Chen, Kui, Cheng, Yuan, Judd, Ted
Published in Journal of medicinal chemistry (28.04.2016)
Published in Journal of medicinal chemistry (28.04.2016)
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Journal Article