Total Syntheses of Vancomycin and Eremomycin Aglycons
Evans, David A., Wood, Michael R., Trotter, B. Wesley, Richardson, Timothy I., Barrow, James C., Katz, Jeffrey L.
Published in Angewandte Chemie International Edition (16.10.1998)
Published in Angewandte Chemie International Edition (16.10.1998)
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Journal Article
In vitro and in vivo evaluation of dihydropyrimidinone C-5 amides as potent and selective alpha(1A) receptor antagonists for the treatment of benign prostatic hyperplasia
Barrow, JC, Nantermet, PG, Selnick, HG, Glass, KL, Rittle, KE, Gilbert, KF, Steele, TG, Homnick, CF, Freidinger, RM, Ransom, RW, Kling, P, Reiss, D, Broten, TP, Schorn, TW, Chang, RSL, O'Malley, SS, Olah, TV, Ellis, JD, Barrish, A, Kassahun, K, Leppert, P, Nagarathnam, D, Forray, C
Published in Journal of medicinal chemistry (13.07.2000)
Published in Journal of medicinal chemistry (13.07.2000)
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Journal Article
Asymmetric Synthesis of the Squalene Synthase Inhibitor Zaragozic Acid C
Evans, David A, Barrow, James C, Leighton, James L, Robichaud, Albert J, Sefkow, Michael
Published in Journal of the American Chemical Society (01.12.1994)
Published in Journal of the American Chemical Society (01.12.1994)
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Journal Article
Discovery and evaluation of potent P-1 aryl heterocycle-based thrombin inhibitors
Young, MB, Barrow, JC, Glass, KL, Lundell, GF, Newton, CL, Pellicore, JM, Rittle, KE, Selnick, HG, Stauffer, KJ, Vacca, JP, Williams, PD, Bohn, D, Clayton, FC, Cook, JJ, Krueger, JA, Kuo, LC, Lewis, SD, Lucas, BJ, McMasters, DR, Miller-Stein, C, Pietrak, BL, Wallace, AA, White, RB, Wong, B, Yan, YW, Nantermet, PG
Published in Journal of medicinal chemistry (03.06.2004)
Published in Journal of medicinal chemistry (03.06.2004)
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Journal Article
Discovery of 4,4-Disubstituted Quinazolin-2-ones as T-Type Calcium Channel Antagonists
Barrow, James C, Rittle, Kenneth E, Reger, Thomas S, Yang, Zhi-Qiang, Bondiskey, Phung, McGaughey, Georgia B, Bock, Mark G, Hartman, George D, Tang, Cuyue, Ballard, Jeanine, Kuo, Yuhsin, Prueksaritanont, Thomayant, Nuss, Cindy E, Doran, Scott M, Fox, Steven V, Garson, Susan L, Kraus, Richard L, Li, Yuxing, Marino, Michael J, Kuzmick Graufelds, Valerie, Uebele, Victor N, Renger, John J
Published in ACS medicinal chemistry letters (13.05.2010)
Published in ACS medicinal chemistry letters (13.05.2010)
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Synthesis and anticonvulsant activity of enaminones: Part 7. Synthesis and anticonvulsant evaluation of ethyl 4-[(substituted phenyl)amino]-6-methyl-2-oxocyclohex-3-ene-1-carboxylates and their corresponding 5-methylcyclohex-2-enone derivatives
Eddington, Natalie D, Cox, Donna S, Khurana, Manoj, Salama, Noha N, Stables, James P, Harrison, Sylvia J, Negussie, Abraham, Taylor, Robert S, Tran, Uy Q, Moore, Jacqueline A, Barrow, Judith C, Scott, K.R
Published in European journal of medicinal chemistry (01.01.2003)
Published in European journal of medicinal chemistry (01.01.2003)
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Journal Article
Synthesis and Evaluation of Imidazole Acetic Acid Inhibitors of Activated Thrombin-Activatable Fibrinolysis Inhibitor as Novel Antithrombotics
Barrow, James C, Nantermet, Philippe G, Stauffer, Shaun R, Ngo, Phung L, Steinbeiser, Melissa A, Mao, Shi-Shan, Carroll, Steven S, Bailey, Carolyn, Colussi, Dennis, Bosserman, Michelle, Burlein, Christine, Cook, Jacquelynn J, Sitko, Gary, Tiller, Philip R, Miller-Stein, Cynthia M, Rose, Mark, McMasters, Daniel R, Vacca, Joseph P, Selnick, Harold G
Published in Journal of medicinal chemistry (04.12.2003)
Published in Journal of medicinal chemistry (04.12.2003)
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Journal Article
Synthesis and Conformational Properties of the M(4-6)(5-7) Bicyclic Tetrapeptide Common to the Vancomycin Antibiotics
Evans, David A, Dinsmore, Christopher J, Ratz, Andrew M, Evrard, Deborah A, Barrow, James C
Published in Journal of the American Chemical Society (09.04.1997)
Published in Journal of the American Chemical Society (09.04.1997)
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Journal Article
Unexpected enhancement of thrombin inhibitor potency with o-aminoalkylbenzylamides in the P1 position
RITTLE, Kenneth E, BARROW, James C, NANTERMET, Philippe G, NEWTON, Christina L, SANDERS, William M, YOUWEI YAN, VACCA, Joseph P, SELNICK, Harold G, CUTRONA, Kellie J, GLASS, Kristen L, KRUEGER, Julie A, KUO, Lawrence C, LEWIS, S. Dale, LUCAS, Bobby J, MCMASTERS, Daniel R, MORRISSETTE, Matthew M
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
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Journal Article
Approaches to the Synthesis of the Vancomycin Antibiotics. Synthesis of Orienticin C (Bis-dechlorovancomycin) Aglycon
Evans, David A, Barrow, James C, Watson, Paul S, Ratz, Andrew M, Dinsmore, Christopher J, Evrard, Deborah A, DeVries, Keith M, Ellman, Jonathan A, Rychnovsky, Scott D, Lacour, Jérôme
Published in Journal of the American Chemical Society (09.04.1997)
Published in Journal of the American Chemical Society (09.04.1997)
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Journal Article
Design and synthesis of potent and selective macrocyclic thrombin inhibitors
Nantermet, Philippe G., Barrow, James C., Newton, Christina L., Pellicore, Janetta M., Young, MaryBeth, Lewis, S.Dale, Lucas, Bobby J., Krueger, Julie A., McMasters, Daniel R., Yan, Youwei, Kuo, Lawrence C., Vacca, Joseph P., Selnick, Harold G.
Published in Bioorganic & medicinal chemistry letters (18.08.2003)
Published in Bioorganic & medicinal chemistry letters (18.08.2003)
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Journal Article
Discovery of a nonpeptidic small molecule antagonist of the human platelet thrombin receptor (PAR-1)
Nantermet, Philippe G, Barrow, James C, Lundell, George F, Pellicore, Janetta M, Rittle, Kenneth E, Young, MaryBeth, Freidinger, Roger M, Connolly, Thomas M, Condra, Cindra, Karczewski, Jerzy, Bednar, Rodney A, Gaul, Stanley L, Gould, Robert J, Prendergast, Kris, Selnick, Harold G
Published in Bioorganic & medicinal chemistry letters (11.02.2002)
Published in Bioorganic & medicinal chemistry letters (11.02.2002)
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Journal Article
Mild nitrosation and hydrolysis of polyfunctional amides
Evans, David A., Carter, Percy H., Dinsmore, Christopher J., Barrow, James C., Katz, Jeffrey L., Kung, Daniel W.
Published in Tetrahedron letters (30.06.1997)
Published in Tetrahedron letters (30.06.1997)
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Journal Article
Discovery and initial structure–Activity relationships of trisubstituted ureas as thrombin receptor (PAR-1) antagonists
Barrow, James C, Nantermet, Philippe G, Selnick, Harold G, Glass, Kristen L, Ngo, Phung L, Young, Mary Beth, Pellicore, Janetta M, Breslin, Michael J, Hutchinson, John H, Freidinger, Roger M, Condra, Cindra, Karczewski, Jerzy, Bednar, Rodney A, Gaul, Stanley L, Stern, Andrew, Gould, Robert, Connolly, Thomas M
Published in Bioorganic & medicinal chemistry letters (22.10.2001)
Published in Bioorganic & medicinal chemistry letters (22.10.2001)
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