Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates
Dong, Yizhou, Love, Kevin T., Dorkin, J. Robert, Sirirungruang, Sasilada, Zhang, Yunlong, Chen, Delai, Bogorad, Roman L., Yin, Hao, Chen, Yi, Vegas, Arturo J., Alabi, Christopher A., Sahay, Gaurav, Olejnik, Karsten T., Wang, Weiheng, Schroeder, Avi, Lytton-Jean, Abigail K. R., Siegwart, Daniel J., Akinc, Akin, Barnes, Carmen, Barros, Scott A., Carioto, Mary, Fitzgerald, Kevin, Hettinger, Julia, Kumar, Varun, Novobrantseva, Tatiana I., Qin, June, Querbes, William, Koteliansky, Victor, Langer, Robert, Anderson, Daniel G.
Published in Proceedings of the National Academy of Sciences - PNAS (18.03.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (18.03.2014)
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Rational design of cationic lipids for siRNA delivery
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Published in Nature biotechnology (01.02.2010)
Published in Nature biotechnology (01.02.2010)
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Shielding of Lipid Nanoparticles for siRNA Delivery: Impact on Physicochemical Properties, Cytokine Induction, and Efficacy
Kumar, Varun, Qin, June, Jiang, Yongfeng, Duncan, Richard G, Brigham, Benjamin, Fishman, Shannon, Nair, Jayaprakash K, Akinc, Akin, Barros, Scott A, Kasperkovitz, Pia V
Published in Molecular therapy. Nucleic acids (2014)
Published in Molecular therapy. Nucleic acids (2014)
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OSWG Recommendations for Genotoxicity Testing of Novel Oligonucleotide-Based Therapeutics
Berman, Cindy L., Barros, Scott A., Galloway, Sheila M., Kasper, Peter, Oleson, Frederick B., Priestley, Catherine C., Sweder, Kevin S., Schlosser, Michael J., Sobol, Zhanna
Published in Nucleic acid therapeutics (01.04.2016)
Published in Nucleic acid therapeutics (01.04.2016)
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Safety evaluation of 2′-deoxy-2′-fluoro nucleotides in GalNAc-siRNA conjugates
Janas, Maja M, Zlatev, Ivan, Liu, Ju, Jiang, Yongfeng, Barros, Scott A, Sutherland, Jessica E, Davis, Wendell P, Liu, Jingxuan, Brown, Christopher R, Liu, Xiumin, Schlegel, Mark K, Blair, Lauren, Zhang, Xuemei, Das, Biplab, Tran, Chris, Aluri, Krishna, Li, Jing, Agarwal, Saket, Indrakanti, Ramesh, Charisse, Klaus, Nair, Jayaprakash, Matsuda, Shigeo, Rajeev, Kallanthottathil G, Zimmermann, Tracy, Sepp-Lorenzino, Laura, Xu, Yuanxin, Akinc, Akin, Fitzgerald, Kevin, Vaishnaw, Akshay K, Smith, Peter F, Manoharan, Muthiah, Jadhav, Vasant, Wu, Jing-Tao, Maier, Martin A
Published in Nucleic acids research (23.04.2019)
Published in Nucleic acids research (23.04.2019)
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Exposure to siRNA-GalNAc Conjugates in Systems of the Standard Test Battery for Genotoxicity
Janas, Maja M., Jiang, Yongfeng, Duncan, Richard G., Hayes, Antoinette N., Liu, Ju, Kasperkovitz, Pia V., Placke, Michael E., Barros, Scott A.
Published in Nucleic acid therapeutics (01.12.2016)
Published in Nucleic acid therapeutics (01.12.2016)
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Activation of Protein Kinase Cζ Increases OAT1 (SLC22A6)- and OAT3 (SLC22A8)-mediated Transport
Barros, Scott A., Srimaroeng, Chutima, Perry, Jennifer L., Walden, Ramsey, Dembla-Rajpal, Neetu, Sweet, Douglas H., Pritchard, John B.
Published in The Journal of biological chemistry (30.01.2009)
Published in The Journal of biological chemistry (30.01.2009)
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Expanded Therapeutic Index Of Antithrombin Silencing and Correction Of Aptt In a Hemophilia A Mouse Model
Barros, Scott A, Carioto, Mary, Hettinger, Julia, Jiang, Yongfeng, Qin, June, Prabhala, Harsha, Sehgal, Alfica, Akinc, Akin
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Activation of Protein Kinase Cζ Increases OAT1 (SLC22A6)- and OAT3 (SLC22A8)-mediated Transport
Scott A. Barros, Chutima Srimaroeng, Jennifer L. Perry, Ramsey Walden, Neetu Dembla-Rajpal, Douglas H. Sweet, John B. Pritchard
Published in The Journal of biological chemistry (30.01.2009)
Published in The Journal of biological chemistry (30.01.2009)
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Activation of protein kinase Czeta increases OAT1 (SLC22A6)- and OAT3 (SLC22A8)-mediated transport
Barros, Scott A, Srimaroeng, Chutima, Perry, Jennifer L, Walden, Ramsey, Dembla-Rajpal, Neetu, Sweet, Douglas H, Pritchard, John B
Published in The Journal of biological chemistry (30.01.2009)
Published in The Journal of biological chemistry (30.01.2009)
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