A tension-mediated glycocalyx–integrin feedback loop promotes mesenchymal-like glioblastoma
Barnes, J. Matthew, Kaushik, Shelly, Bainer, Russell O., Sa, Jason K., Woods, Elliot C., Kai, FuiBoon, Przybyla, Laralynne, Lee, Mijeong, Lee, Hye Won, Tung, Jason C., Maller, Ori, Barrett, Alexander S., Lu, Kan V., Lakins, Jonathon N., Hansen, Kirk C., Obernier, Kirsten, Alvarez-Buylla, Arturo, Bergers, Gabriele, Phillips, Joanna J., Nam, Do-Hyun, Bertozzi, Carolyn R., Weaver, Valerie M.
Published in Nature cell biology (01.10.2018)
Published in Nature cell biology (01.10.2018)
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Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217
Northey, Jason J, Barrett, Alexander S, Acerbi, Irene, Hayward, Mary-Kate, Talamantes, Stephanie, Dean, Ivory S, Mouw, Janna K, Ponik, Suzanne M, Lakins, Jonathon N, Huang, Po-Jui, Wu, Junmin, Shi, Quanming, Samson, Susan, Keely, Patricia J, Mukhtar, Rita A, Liphardt, Jan T, Shepherd, John A, Hwang, E Shelley, Chen, Yunn-Yi, Hansen, Kirk C, Littlepage, Laurie E, Weaver, Valerie M
Published in The Journal of clinical investigation (01.11.2020)
Published in The Journal of clinical investigation (01.11.2020)
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Targeting HER2/HER3 co‐mutations in metastatic breast cancer: Case reports of exceptional responders to trastuzumab and pertuzumab therapy
Blas, Page E., Rodriguez, Esther San Roman, Williams, Heather L., Levin, Maren K., Bell, Joshua S. K., Pierobon, Mariaelena, Barrett, Alexander S., Petricoin, Emanuel F., O'Shaughnessy, Joyce A.
Published in Cancer reports (01.03.2024)
Published in Cancer reports (01.03.2024)
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Journal Article
Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression
Maller, Ori, Drain, Allison P., Barrett, Alexander S., Borgquist, Signe, Ruffell, Brian, Zakharevich, Igor, Pham, Thanh T., Gruosso, Tina, Kuasne, Hellen, Lakins, Johnathon N., Acerbi, Irene, Barnes, J. Matthew, Nemkov, Travis, Chauhan, Aastha, Gruenberg, Jessica, Nasir, Aqsa, Bjarnadottir, Olof, Werb, Zena, Kabos, Peter, Chen, Yunn-Yi, Hwang, E. Shelley, Park, Morag, Coussens, Lisa M., Nelson, Andrew C., Hansen, Kirk C., Weaver, Valerie M.
Published in Nature materials (01.04.2021)
Published in Nature materials (01.04.2021)
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Journal Article
Hydroxylamine Chemical Digestion for Insoluble Extracellular Matrix Characterization
Barrett, Alexander S, Wither, Matthew J, Hill, Ryan C, Dzieciatkowska, Monika, D’Alessandro, Angelo, Reisz, Julie A, Hansen, Kirk C
Published in Journal of proteome research (03.11.2017)
Published in Journal of proteome research (03.11.2017)
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Journal Article
Fibroblast subtypes define a metastatic matrisome in breast cancer
Brechbuhl, Heather M., Barrett, Alexander S., Kopin, Etana, Hagen, Jaime C., Han, Amy L., Gillen, Austin E., Finlay-Schultz, Jessica, Cittelly, Diana M., Owens, Philip, Horwitz, Kathryn B., Sartorius, Carol A., Hansen, Kirk, Kabos, Peter
Published in JCI insight (27.02.2020)
Published in JCI insight (27.02.2020)
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Journal Article
Mammary collagen is under reproductive control with implications for breast cancer
Guo, Qiuchen, Sun, Duanchen, Barrett, Alexander S., Jindal, Sonali, Pennock, Nathan D., Conklin, Matthew W., Xia, Zheng, Mitchell, Elizabeth, Samatham, Ravikant, Mirza, Naomi, Jacques, Steven, Weinmann, Sheila, Borges, Virginia F., Hansen, Kirk C., Schedin, Pepper J.
Published in Matrix biology (01.01.2022)
Published in Matrix biology (01.01.2022)
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Structural Insight into Recognition of Methylated Histone H3K4 by Set3
Gatchalian, Jovylyn, Ali, Muzaffar, Andrews, Forest H., Zhang, Yi, Barrett, Alexander S., Kutateladze, Tatiana G.
Published in Journal of molecular biology (30.06.2017)
Published in Journal of molecular biology (30.06.2017)
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When nature's robots go rogue: exploring protein homeostasis dysfunction and the implications for understanding human aging disease pathologies
Reisz, Julie A, Barrett, Alexander S, Nemkov, Travis, Hansen, Kirk C, D'Alessandro, Angelo
Published in Expert review of proteomics (03.04.2018)
Published in Expert review of proteomics (03.04.2018)
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Journal Article
Fibroblast subtypes define a metastatic matrisome in breast cancer
Brechbuhl, Heather M, Barrett, Alexander S, Kopin, Etana, Hagen, Jaime C, Han, Amy L, Gillen, Austin E, Finlay-Schultz, Jessica, Cittelly, Diana M, Owens, Philip, Horwitz, Kathryn B, Sartorius, Carol A, Hansen, Kirk, Kabos, Peter
Published in JCI insight (27.02.2020)
Published in JCI insight (27.02.2020)
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Journal Article
Landscape of KRAS G12C , Associated Genomic Alterations, and Interrelation With Immuno-Oncology Biomarkers in KRAS -Mutated Cancers
Salem, Mohamed E, El-Refai, Sherif M, Sha, Wei, Puccini, Alberto, Grothey, Axel, George, Thomas J, Hwang, Jimmy J, O'Neil, Bert, Barrett, Alexander S, Kadakia, Kunal C, Musselwhite, Laura W, Raghavan, Derek, Van Cutsem, Eric, Tabernero, Josep, Tie, Jeanne
Published in JCO precision oncology (01.05.2022)
Published in JCO precision oncology (01.05.2022)
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Journal Article
Compartment resolved proteomics reveals a dynamic matrisome in a biomechanically driven model of pancreatic ductal adenocarcinoma
Barrett, Alexander S, Maller, Ori, Pickup, Michael W, Weaver, Valerie M, Hansen, Kirk C
Published in Journal of immunology and regenerative medicine (01.03.2018)
Published in Journal of immunology and regenerative medicine (01.03.2018)
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Journal Article
Inflammation promotes tumor aggression by stimulating stromal cell-dependent collagen crosslinking and stromal stiffening
Maller, Ori, Drain, Allison P, Barrett, Alexander S, Borgquist, Signe, Ruffell, Brian, Thanh, Pham T, Gruosso, Tina, Kuasne, Hellen, Lakins, Johnathon N, Acerbi, Irene, Barnes, J Matthew, Nemkov, Travis, Chauhan, Aastha, Gruenberg, Jessica, Nasir, Aqsa, Bjarnadottir, Olof, Werb, Zena, Kabos, Peter, E Shelley Hwang, Park, Morag, Coussens, Lisa M, Nelson, Andrew C, Hansen, Kirk C, Weaver, Valerie M
Published in bioRxiv (13.02.2020)
Published in bioRxiv (13.02.2020)
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