Chemosensitization of cancer cells by KU-0060648, a dual inhibitor of DNA-PK and PI-3K
Munck, Joanne M, Batey, Michael A, Zhao, Yan, Jenkins, Helen, Richardson, Caroline J, Cano, Celine, Tavecchio, Michele, Barbeau, Jody, Bardos, Julia, Cornell, Liam, Griffin, Roger J, Menear, Keith, Slade, Andrew, Thommes, Pia, Martin, Niall M B, Newell, David R, Smith, Graeme C M, Curtin, Nicola J
Published in Molecular cancer therapeutics (01.08.2012)
Published in Molecular cancer therapeutics (01.08.2012)
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DNA-dependent protein kinase (DNA-PK) inhibitors: Structure–activity relationships for O-alkoxyphenylchromen-4-one probes of the ATP-binding domain
Clapham, Kate M., Bardos, Julia, Finlay, M. Raymond V., Golding, Bernard T., Griffen, Edward J., Griffin, Roger J., Hardcastle, Ian R., Menear, Keith A., Ting, Attilla, Turner, Paul, Young, Gail L., Cano, Céline
Published in Bioorganic & medicinal chemistry letters (01.02.2011)
Published in Bioorganic & medicinal chemistry letters (01.02.2011)
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1-Substituted (Dibenzo[ b,d ]thiophen-4-yl)-2-morpholino-4 H -chromen-4-ones Endowed with Dual DNA-PK/PI3-K Inhibitory Activity
Cano, Céline, Saravanan, Kappusamy, Bailey, Chris, Bardos, Julia, Curtin, Nicola J., Frigerio, Mark, Golding, Bernard T., Hardcastle, Ian R., Hummersone, Marc G., Menear, Keith A., Newell, David R., Richardson, Caroline J., Shea, K., Smith, Graeme C. M., Thommes, Pia, Ting, Attilla, Griffin, Roger J.
Published in Journal of medicinal chemistry (22.08.2013)
Published in Journal of medicinal chemistry (22.08.2013)
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Journal Article
1‑Substituted (Dibenzo[b,d]thiophen-4-yl)-2-morpholino‑4H‑chromen-4-ones Endowed with Dual DNA-PK/PI3‑K Inhibitory Activity
Cano, Céline, Saravanan, Kappusamy, Bailey, Chris, Bardos, Julia, Curtin, Nicola J, Frigerio, Mark, Golding, Bernard T, Hardcastle, Ian R, Hummersone, Marc G, Menear, Keith A, Newell, David R, Richardson, Caroline J, Shea, K, Smith, Graeme C. M, Thommes, Pia, Ting, Attilla, Griffin, Roger J
Published in Journal of medicinal chemistry (22.08.2013)
Published in Journal of medicinal chemistry (22.08.2013)
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Growth Factor-Mediated Induction of HDM2 Positively Regulates Hypoxia-Inducible Factor 1α Expression
Bárdos, Julia I., Chau, Noan-Minh, Ashcroft, Margaret
Published in Molecular and Cellular Biology (01.04.2004)
Published in Molecular and Cellular Biology (01.04.2004)
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Potent enantioselective inhibition of DNA-dependent protein kinase (DNA-PK) by atropisomeric chromenone derivatives
Clapham, Kate M., Rennison, Tommy, Jones, Gavin, Craven, Faye, Bardos, Julia, Golding, Bernard T., Griffin, Roger J., Haggerty, Karen, Hardcastle, Ian R., Thommes, Pia, Ting, Attilla, Cano, Celine
Published in Organic & biomolecular chemistry (07.09.2012)
Published in Organic & biomolecular chemistry (07.09.2012)
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Mapping the ATP-binding domain of DNA-dependent protein kinase (DNA-PK) with coumarin- and isocoumarin-derived inhibitors
Payne, Sara L., Rodriguez-Aristegui, Sonsoles, Bardos, Julia, Cano, Céline, Golding, Bernard T., Hardcastle, Ian R., Peacock, Marcus, Parveen, Nahida, Griffin, Roger J.
Published in Bioorganic & medicinal chemistry letters (15.06.2010)
Published in Bioorganic & medicinal chemistry letters (15.06.2010)
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Potent enantioselective inhibition of DNA-dependent protein kinase (DNA-PK) by atropisomeric chromenone derivativesElectronic supplementary information (ESI) available. See DOI: 10.1039/c2ob26035b
Clapham, Kate M, Rennison, Tommy, Jones, Gavin, Craven, Faye, Bardos, Julia, Golding, Bernard T, Griffin, Roger J, Haggerty, Karen, Hardcastle, Ian R, Thommes, Pia, Ting, Attilla, Cano, Céline
Year of Publication 01.08.2012
Year of Publication 01.08.2012
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Abstract A116: Radio- and chemosensitization through inhibition of DNA-PK by KU-0060648
Bardos, Julia, Shea, Kerry, Parveen, Nahida, Peacock, Marcus, Deacon, William, Cranston, Aaron, Albertella, Mark, Menear, Keith, Smith, Graeme, Martin, Niall
Published in Molecular cancer therapeutics (10.12.2009)
Published in Molecular cancer therapeutics (10.12.2009)
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Journal Article
Abstract 2548: Chemosensitization of cancer cells by KU-0060648: A dual inhibitor of DNA-PK and PI-3K
Batey, Michael A., Munck, Joanne M., Zhao, Yan, Cano, Celine, Tavecchio, Michele, Bardos, Julia, Griffin, Roger J., Jenkins, Helen, Menear, Keith, Smith, Graeme, Thommes, Pia, Newell, David R., Martin, Niall, Curtin, Nicola J.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Abstract 5780: Development of potent inhibitors of the DNA-dependent protein kinase (DNA-PK)
Cano, Celine, Bailey, Chris, Bardos, Julia, Curtin, Nicola, Frigerio, Mark, Golding, Bernard, Hardcastle, Ian, Hummersone, Marc, Menear, Keith, Newell, David, Saravanan, Kappusamy, Shea, K, Smith, Graeme, Griffin, Roger
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Journal Article
Chemosensitisation of cancer cells by KU-0060648; a dual inhibitor of DNA-PK and PI-3K
Munck, Joanne M., Batey, Michael A., Zhao, Yan, Jenkins, Helen, Richardson, Caroline J., Cano, Celine, Tavecchio, Michele, Barbeau, Jody, Bardos, Julia, Cornell, Liam, Griffin, Roger J., Menear, Keith, Slade, Andrew, Thommes, Pia, Martin, Niall MB, Newell, David R, Smith, Graeme CM, Curtin, Nicola J
Published in Molecular cancer therapeutics (10.05.2012)
Published in Molecular cancer therapeutics (10.05.2012)
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Isolation, sequencing and expression of RED, a novel human gene encoding an acidic–basic dipeptide repeat
Assier, Eric, Bouzinba-Segard, Haniaa, Stolzenberg, Marie-Claude, Stephens, Richard, Bardos, Julia, Freemont, Paul, Charron, Dominique, Trowsdale, John, Rich, Tina
Published in Gene (16.04.1999)
Published in Gene (16.04.1999)
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Novel exon connections of the brain‐specific (BS) exon of the adenomatous polyposis coli gene
Bardos, Julia, Sulekova, Zora, Ballhausen, Wolfgang G.
Published in International journal of cancer (26.09.1997)
Published in International journal of cancer (26.09.1997)
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Abstract 3928: KU-0060019, a novel small molecule inhibitor of ATM
Shea, Kerry F., Albertella, Mark, Bárdos, Julia, Batey, Michael A., Cranston, Aaron, Curtin, Nicola, Griffin, Roger, Lau, Alan, Menear, Keith, Newell, David, O'Connor, Mark, Richardson, Caroline, Jones, Louise, Smith, Graeme, Thömmes, Pia, Zhao, Yan, Martin, Niall
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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HPC3 Is a New Human Polycomb Orthologue That Interacts and Associates with RING1 and Bmi1 and Has Transcriptional Repression Properties
Bárdos, Julia I., Saurin, Andrew J., Tissot, Catherine, Duprez, Estelle, Freemont, Paul S.
Published in The Journal of biological chemistry (15.09.2000)
Published in The Journal of biological chemistry (15.09.2000)
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