An Update On Mdmx And Dual Mdm2/X Inhibitors
Espadinha, Margarida, Barcherini, Valentina, Lopes, Elizabeth A, Santos, Maria M M
Published in Current topics in medicinal chemistry (01.01.2018)
Published in Current topics in medicinal chemistry (01.01.2018)
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Journal Article
SLMP53-1 Inhibits Tumor Cell Growth through Regulation of Glucose Metabolism and Angiogenesis in a P53-Dependent Manner
Ramos, Helena, Calheiros, Juliana, Almeida, Joana, Barcherini, Valentina, Santos, Sónia, Carvalho, Alexandra T P, Santos, Maria M M, Saraiva, Lucília
Published in International journal of molecular sciences (17.01.2020)
Published in International journal of molecular sciences (17.01.2020)
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Journal Article
Metabolism-Guided Optimization of Tryptophanol-Derived Isoindolinone p53 Activators
Barcherini, Valentina, Loureiro, Joana B, Sena, Ana, Madeira, Catarina, Leandro, Paula, Saraiva, Lucília, Antunes, Alexandra M M, Santos, Maria M M
Published in Pharmaceuticals (Basel, Switzerland) (19.01.2023)
Published in Pharmaceuticals (Basel, Switzerland) (19.01.2023)
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Tryptophanol-Derived Oxazolopyrrolidone Lactams as Potential Anticancer Agents against Gastric Adenocarcinoma
Espadinha, Margarida, Barcherini, Valentina, Gonçalves, Lídia M, Molins, Elies, Antunes, Alexandra M M, Santos, Maria M M
Published in Pharmaceuticals (Basel, Switzerland) (02.03.2021)
Published in Pharmaceuticals (Basel, Switzerland) (02.03.2021)
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Journal Article
SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma
Gomes, Sara, Bosco, Bartolomeo, Loureiro, Joana B, Ramos, Helena, Raimundo, Liliana, Soares, Joana, Nazareth, Nair, Barcherini, Valentina, Domingues, Lucília, Oliveira, Carla, Bisio, Alessandra, Piazza, Silvano, Bauer, Matthias R, Brás, João P, Almeida, Maria Inês, Gomes, Célia, Reis, Flávio, Fersht, Alan R, Inga, Alberto, Santos, Maria M M, Saraiva, Lucília
Published in Cancers (10.08.2019)
Published in Cancers (10.08.2019)
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First fragment-based screening identifies new chemotypes inhibiting ERAP1-metalloprotease
Fougiaxis, Vasileios, Barcherini, Valentina, Petrovic, Milena M., Sierocki, Pierre, Warenghem, Sandrine, Leroux, Florence, Bou Karroum, Nour, Petit-Cancelier, Fabien, Rodeschini, Vincent, Roche, Didier, Deprez, Benoit, Deprez-Poulain, Rebecca
Published in European journal of medicinal chemistry (15.12.2024)
Published in European journal of medicinal chemistry (15.12.2024)
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Abstract P030: Chemoprevention by the mutant p53 reactivator SLMP53-2 on ultraviolet radiation-induced skin cancer
Loureiro, Joana B., Ribeiro, Rita, Nazareth, Nair, Ferreira, Tiago, Quaresma, Adelina, Barcherini, Valentina, Marabini, Laura, Oliveira, Paula A., Santos, Maria M. M., Saraiva, Lucília
Published in Molecular cancer therapeutics (01.12.2021)
Published in Molecular cancer therapeutics (01.12.2021)
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Journal Article
SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations
Gomes, Ana Sara, Ramos, Helena, Gomes, Sara, Loureiro, Joana B., Soares, Joana, Barcherini, Valentina, Monti, Paola, Fronza, Gilberto, Oliveira, Carla, Domingues, Lucília, Bastos, Margarida, Dourado, Daniel F.A.R., Carvalho, Ana Luísa, Romão, Maria João, Pinheiro, Benedita, Marcelo, Filipa, Carvalho, Alexandra, Santos, Maria M.M., Saraiva, Lucília
Published in Biochimica et biophysica acta. General subjects (01.01.2020)
Published in Biochimica et biophysica acta. General subjects (01.01.2020)
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Journal Article
Potency and Selectivity Optimization of Tryptophanol‐Derived Oxazoloisoindolinones: Novel p53 Activators in Human Colorectal Cancer
Barcherini, Valentina, Almeida, Joana, Lopes, Elizabeth A., Wang, Mi, Magalhães e Silva, Diogo, Mori, Mattia, Wang, Shaomeng, Saraiva, Lucília, Santos, Maria M. M.
Published in ChemMedChem (08.01.2021)
Published in ChemMedChem (08.01.2021)
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Targeting p53 for Melanoma Treatment: Counteracting Tumour Proliferation, Dissemination and Therapeutic Resistance
Loureiro, Joana B, Raimundo, Liliana, Calheiros, Juliana, Carvalho, Carla, Barcherini, Valentina, Lima, Nuno R, Gomes, Célia, Almeida, Maria Inês, Alves, Marco G, Costa, José Luís, Santos, Maria M M, Saraiva, Lucília
Published in Cancers (01.04.2021)
Published in Cancers (01.04.2021)
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Targeting p53 for melanoma treatment: counteracting tumour proliferation, dissemination and therapeutic resistance
Loureiro, Joana B., Raimundo, Liliana, Calheiros, Juliana, Carvalho, Carla, Barcherini, Valentina, Lima, Nuno R., Gomes, Célia, Almeida, Maria Inês, Alves, Marco G., Costa, José Luís, Santos, Maria M. M., Saraiva, Lucília
Published in Cancers (01.04.2021)
Published in Cancers (01.04.2021)
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