Identification of the Clinical Candidate PF-07284890 (ARRY-461), a Highly Potent and Brain Penetrant BRAF Inhibitor for the Treatment of Cancer
Ren, Li, Moreno, David, Baer, Brian R., Barbour, Patrick, Bettendorf, Tanna, Bouhana, Karyn, Brown, Karin, Brown, Suzy A., Fell, Jay B., Hartley, Dylan P., Hicken, Erik J., Laird, Ellen R., Lee, Patrice, McCown, Joseph, Otten, Jennifer N., Prigaro, Brett, Wallace, Ross, Kahn, Dean
Published in Journal of medicinal chemistry (08.08.2024)
Published in Journal of medicinal chemistry (08.08.2024)
Get full text
Journal Article
BRAF-관련 질환 및 장애의 치료를 위한 4-옥소-3,4-다이하이드로퀸아졸린온 화합물
LAIRD ELLEN RUTH, BETTENDORF TANNA MARIE, REN LI, DOERNER BARBOUR PATRICK MICHAEL, KAHN DEAN RUSSELL, KELLUM ALEX ANDREW, MORENO DAVID AUSTIN
Year of Publication 09.02.2023
Get full text
Year of Publication 09.02.2023
Patent
MEK 34--27--162H7H-34-DIHYDRO-27-NAPHTHYRIDINE-162H7H-DIONES AS MEK INHIBITORS
WITKOS FAITH ELIZABETH, CLARK WESLEY DEWITT, KELLUM ALEX ANDREW, BLAKE JAMES FRANCIS, DAHLKE JOSHUA RYAN, BOYS MARK LAURENCE, COWDREY CONNOR JAMES, KNAPP ELLEN MARGARET, BLANCHE SYDNEY TAYLOR, ALLEN SHELLEY, REN LI, DOERNER BARBOUR PATRICK MICHAEL, MORENO DAVID AUSTIN, FULTON JENNIFER LYNN, O'LEARY JACOB MATTHEW
Year of Publication 03.04.2024
Get full text
Year of Publication 03.04.2024
Patent
TAM 및 MET 키나제의 억제제로서 피라졸로[3,4-b]피리딘 화합물
HINKLIN RONALD JAY, ALLEN SHELLEY, DAHLKE JOSHUA, MCNULTY OREN T, LAIRD ELLEN, BARBOUR PATRICK, ZHAO QIAN, GAUDINO JOHN, COOK ADAM
Year of Publication 06.05.2021
Get full text
Year of Publication 06.05.2021
Patent
MEK 억제제로서의 3,4-디히드로-2,7-나프티리딘-1,6(2H,7H)-디온
WITKOS FAITH ELIZABETH, CLARK WESLEY DEWITT, KELLUM ALEX ANDREW, BLAKE JAMES FRANCIS, DAHLKE JOSHUA RYAN, BOYS MARK LAURENCE, COWDREY CONNOR JAMES, KNAPP ELLEN MARGARET, BLANCHE SYDNEY TAYLOR, ALLEN SHELLEY, REN LI, DOERNER BARBOUR PATRICK MICHAEL, MORENO DAVID AUSTIN, FULTON JENNIFER LYNN, O'LEARY JACOB MATTHEW
Year of Publication 19.10.2023
Get full text
Year of Publication 19.10.2023
Patent
BRAF-연관 질환 및 장애의 치료에 유용한 퀴나졸린-4-온 유도체
NEWHOUSE BRADLEY JON, LAIRD ELLEN RUTH, TARLTON EUGENE, KAHN DEAN RUSSELL, BARBOUR PATRICK MICHAEL, HICKEN ERIK JAMES, PRIGARO BRETT JOSEPH, REN LI, PAJK SPENCER PHILLIP, COOK ADAM WADE, MORENO DAVID AUSTIN, METCALF ANDREW TERRANCE, BROWN KATIE KEATON
Year of Publication 28.01.2022
Get full text
Year of Publication 28.01.2022
Patent
PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS AS INHIBITORS OF TAM AND MET KINASES
HINKLIN, Ronald Jay, ALLEN, Shelley, LAIRD, Ellen, COOK, Adam, BARBOUR, Patrick, ZHAO, Qian, DAHLKE, Joshua, GAUDINO, John, MCNULTY, Oren T
Year of Publication 15.11.2023
Get full text
Year of Publication 15.11.2023
Patent
PYRAZOLO[3,4-b]PYRIDINE COMPOUNDS AS INHIBITORS OF TAM AND MET KINASES
HINKLIN, Ronald Jay, ALLEN, Shelley, LAIRD, Ellen, COOK, Adam, BARBOUR, Patrick, ZHAO, Qian, DAHLKE, Joshua, GAUDINO, John, MCNULTY, Oren T
Year of Publication 02.11.2023
Get full text
Year of Publication 02.11.2023
Patent
Pyrazolo[3,4-b]pyridine compounds as inhibitors of TAM and MET kinases
Barbour, Patrick, Dahlke, Joshua, Zhao, Qian, Allen, Shelley, McNulty, Oren T, Cook, Adam, Laird, Ellen, Hinklin, Ronald Jay, Gaudino, John
Year of Publication 10.10.2023
Get full text
Year of Publication 10.10.2023
Patent