Tetrahydroquinoline Derivatives as Potent and Selective Factor XIa Inhibitors
Quan, Mimi L, Wong, Pancras C, Wang, Cailan, Woerner, Francis, Smallheer, Joanne M, Barbera, Frank A, Bozarth, Jeffrey M, Brown, Randi L, Harpel, Mark R, Luettgen, Joseph M, Morin, Paul E, Peterson, Tara, Ramamurthy, Vidhyashankar, Rendina, Alan R, Rossi, Karen A, Watson, Carol A, Wei, Anzhi, Zhang, Ge, Seiffert, Dietmar, Wexler, Ruth R
Published in Journal of medicinal chemistry (13.02.2014)
Published in Journal of medicinal chemistry (13.02.2014)
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Phenylimidazoles as Potent and Selective Inhibitors of Coagulation Factor XIa with in Vivo Antithrombotic Activity
Hangeland, Jon J, Friends, Todd J, Rossi, Karen A, Smallheer, Joanne M, Wang, Cailan, Sun, Zhong, Corte, James R, Fang, Tianan, Wong, Pancras C, Rendina, Alan R, Barbera, Frank A, Bozarth, Jeffrey M, Luettgen, Joseph M, Watson, Carol A, Zhang, Ge, Wei, Anzhi, Ramamurthy, Vidhyashankar, Morin, Paul E, Bisacchi, Gregory S, Subramaniam, Srinath, Arunachalam, Piramanayagam, Mathur, Arvind, Seiffert, Dietmar A, Wexler, Ruth R, Quan, Mimi L
Published in Journal of medicinal chemistry (11.12.2014)
Published in Journal of medicinal chemistry (11.12.2014)
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Pyridine and pyridinone-based factor XIa inhibitors
Corte, James R., Fang, Tianan, Hangeland, Jon J., Friends, Todd J., Rendina, Alan R., Luettgen, Joseph M., Bozarth, Jeffrey M., Barbera, Frank A., Rossi, Karen A., Wei, Anzhi, Ramamurthy, Vidhyashankar, Morin, Paul E., Seiffert, Dietmar A., Wexler, Ruth R., Quan, Mimi L.
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
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Design and synthesis of bicyclic pyrazinone and pyrimidinone amides as potent TF–FVIIa inhibitors
Zhang, Xiaojun, Glunz, Peter W., Jiang, Wen, Schmitt, Aaron, Newman, Makenzie, Barbera, Frank A., Bozarth, Jeffery M., Rendina, Alan R., Wei, Anzhi, Wen, Xiao, Rossi, Karen A., Luettgen, Joseph M., Wong, Pancras C., Knabb, Robert M., Wexler, Ruth R., Scott Priestley, E.
Published in Bioorganic & medicinal chemistry letters (15.03.2013)
Published in Bioorganic & medicinal chemistry letters (15.03.2013)
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Comparative Analysis of Various Platelet Glycoprotein IIb/IIIa Antagonists on Shear-Induced Platelet Activation and Adhesion
Wang, Xinkang, Dorsam, Robert T, Lauver, Adam, Wang, Hugh, Barbera, Frank A, Gibbs, Sandra, Varon, David, Savion, Naphtali, Friedman, Steven M, Feuerstein, Giora Z
Published in The Journal of pharmacology and experimental therapeutics (01.12.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2002)
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Effects of plasma kallikrein deficiency on haemostasis and thrombosis in mice: murine ortholog of the Fletcher trait
Bird, J Eileen, Smith, Patricia L, Wang, Xinkang, Schumacher, William A, Barbera, Frank, Revelli, Jean-Pierre, Seiffert, Dietmar
Published in Thrombosis and haemostasis (01.06.2012)
Published in Thrombosis and haemostasis (01.06.2012)
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Disubstituted Indazoles as Potent Antagonists of the Integrin αvβ3
Batt, Douglas G, Petraitis, Joseph J, Houghton, Gregory C, Modi, Dilip P, Cain, Gary A, Corjay, Martha H, Mousa, Shaker A, Bouchard, Peter J, Forsythe, Mark S, Harlow, Patricia P, Barbera, Frank A, Spitz, Susan M, Wexler, Ruth R, Jadhav, Prabhakar K
Published in Journal of medicinal chemistry (13.01.2000)
Published in Journal of medicinal chemistry (13.01.2000)
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A platelet target for venous thrombosis? P2Y1 deletion or antagonism protects mice from vena cava thrombosis
Bird, J. Eileen, Wang, Xinkang, Smith, Patricia L., Barbera, Frank, Huang, Christine, Schumacher, William A.
Published in Journal of thrombosis and thrombolysis (01.08.2012)
Published in Journal of thrombosis and thrombolysis (01.08.2012)
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Prediction of the therapeutic index of marketed anti-coagulants and anti-platelet agents by guinea pig models of thrombosis and hemostasis
Bird, J. Eileen, Giancarli, Mary R, Allegretto, Nick, Barbera, Frank, Wong, Pancras, Schumacher, William A, Ogletree, Martin L, Seiffert, Dietmar
Published in Thrombosis research (2008)
Published in Thrombosis research (2008)
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SAR and factor IXa crystal structure of a dual inhibitor of factors IXa and Xa
SMALLHEER, Joanne M, ALEXANDER, Richard S, KNABB, Robert M, WEXLER, Ruth R, JADHAV, Prabhakar K, JIANMIN WANG, SHUAIGE WANG, NAKAJIMA, Suanne, ROSSI, Karen A, SMALLWOOD, Angela, BARBERA, Frank, BURDICK, Debra, LUETTGEN, Joseph M
Published in Bioorganic & medicinal chemistry letters (01.11.2004)
Published in Bioorganic & medicinal chemistry letters (01.11.2004)
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In Vitro Evaluation of Apixaban, a Novel, Potent, Selective and Orally Bioavailable Factor Xa Inhibitor
Luettgen, Joseph M., Bozarth, Tracy A., Bozarth, Jeffrey M., Barbera, Frank A., Lam, Patrick Y., Quan, Mimi L., Pinto, Donald J., Wexler, Ruth R., Rendina, Alan R., Knabb, Robert M.
Published in Blood (16.11.2006)
Published in Blood (16.11.2006)
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Identification and concerted function of two receptor binding surfaces on basic fibroblast growth factor required for mitogenesis
Springer, B A, Pantoliano, M W, Barbera, F A, Gunyuzlu, P L, Thompson, L D, Herblin, W F, Rosenfeld, S A, Book, G W
Published in The Journal of biological chemistry (28.10.1994)
Published in The Journal of biological chemistry (28.10.1994)
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Disubstituted Indazoles as Potent Antagonists of the Integrin α v β 3
Batt, Douglas G., Petraitis, Joseph J., Houghton, Gregory C., Modi, Dilip P., Cain, Gary A., Corjay, Martha H., Mousa, Shaker A., Bouchard, Peter J., Forsythe, Mark S., Harlow, Patricia P., Barbera, Frank A., Spitz, Susan M., Wexler, Ruth R., Jadhav, Prabhakar K.
Published in Journal of medicinal chemistry (01.01.2000)
Published in Journal of medicinal chemistry (01.01.2000)
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A novel angiotensin II binding site in murine tissues
Herblin, William F., Barbera, Frank, Diamond, Sheila, Gibson, Raymond E., Timmermans, Peter
Published in Life sciences (1973) (1998)
Published in Life sciences (1973) (1998)
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Prothrombin Activation in Rabbits
Seiffert, Dietmar, Mitchell, Thomas J., Wang, Zhaoyuan, Knabb, Robert M., Barbera, Frank, Reilly, Thomas M., Thoolen, Martin
Published in Thrombosis research (01.02.1999)
Published in Thrombosis research (01.02.1999)
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Nonpeptide angiotensin II receptor antagonists: in vivo inhibition of [125I-Sar1,Ile8]angiotensin II binding by losartan, EXP597 and L-159,282 in rats
Wong, P C, Herblin, W F, Barbera, F A, Bernard, R, Bozarth, T A, Watson, C A, Gibson, R E
Published in Clinical and experimental hypertension (1993) (1996)
Published in Clinical and experimental hypertension (1993) (1996)
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Factors in acute hypotension and ventricular fibrillation after cardiac necrosis
Barrera, F, Ascanio, G, Lautsch, E V, Oppenheimer, M J
Published in The American journal of the medical sciences (01.06.1967)
Published in The American journal of the medical sciences (01.06.1967)
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