3-Substituted Quinolines as RORγt Inverse Agonists
Tanis, Virginia M., Venkatesan, Hariharan, Cummings, Maxwell D., Albers, Michael, Kent Barbay, J., Herman, Krystal, Kummer, David A., Milligan, Cynthia, Nelen, Marina I., Nishimura, Rachel, Schlueter, Thomas, Scott, Brian, Spurlino, John, Wolin, Ronald, Woods, Craig, Xue, Xiaohua, Edwards, James P., Fourie, Anne M., Leonard, Kristi
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Published in Bioorganic & medicinal chemistry letters (15.06.2019)
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Synthesis and characterization of 5,6,7,8-tetrahydroquinoline C5a receptor antagonists
Barbay, J. Kent, Gong, Yong, Buntinx, Mieke, Li, Jian, Claes, Concha, Hornby, Pamela J., Van Lommen, Guy, Van Wauwe, Jean, He, Wei
Published in Bioorganic & medicinal chemistry (15.04.2008)
Published in Bioorganic & medicinal chemistry (15.04.2008)
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Design and optimization of aniline-substituted tetrahydroquinoline C5a receptor antagonists
Gong, Yong, Barbay, J. Kent, Buntinx, Mieke, Li, Jian, Wauwe, Jean Van, Claes, Concha, Lommen, Guy Van, Hornby, Pamela J., He, Wei
Published in Bioorganic & medicinal chemistry (15.07.2008)
Published in Bioorganic & medicinal chemistry (15.07.2008)
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Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase
Tichenor, Mark S., Wiener, John J. M., Rao, Navin L., Bacani, Genesis M., Wei, Jianmei, Pooley Deckhut, Charlotte, Barbay, J. Kent, Kreutter, Kevin D., Chang, Leon, Clancy, Kathleen W., Murrey, Heather E., Wang, Weixue, Ahn, Kay, Huber, Michael, Rex, Elizabeth, Coe, Kevin J., Wu, Jiejun, Rui, Haopeng, Sepassi, Kia, Gaudiano, Marcello, Bekkers, Mariette, Cornelissen, Ivo, Packman, Kathryn, Seierstad, Mark, Xiouras, Christos, Bembenek, Scott D., Alexander, Richard, Milligan, Cynthia, Balasubramanian, Sriram, Lebsack, Alec D., Venable, Jennifer D., Philippar, Ulrike, Edwards, James P., Hirst, Gavin
Published in Journal of medicinal chemistry (10.11.2022)
Published in Journal of medicinal chemistry (10.11.2022)
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6-Substituted quinolines as RORγt inverse agonists
Barbay, J. Kent, Cummings, Maxwell D., Abad, Marta, Castro, Glenda, Kreutter, Kevin D., Kummer, David A., Maharoof, Umar, Milligan, Cynthia, Nishimura, Rachel, Pierce, Joan, Schalk-Hihi, Celine, Spurlino, John, Tanis, Virginia M., Urbanski, Maud, Venkatesan, Hariharan, Wang, Aihua, Woods, Craig, Wolin, Ronald, Xue, Xiaohua, Edwards, James P., Fourie, Anne M., Leonard, Kristi
Published in Bioorganic & medicinal chemistry letters (01.12.2017)
Published in Bioorganic & medicinal chemistry letters (01.12.2017)
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Discovery of a Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase with Oral Anti-Inflammatory Activity
Tichenor, Mark S, Wiener, John J. M, Rao, Navin L, Pooley Deckhut, Charlotte, Barbay, J. Kent, Kreutter, Kevin D, Bacani, Genesis M, Wei, Jianmei, Chang, Leon, Murrey, Heather E, Wang, Weixue, Ahn, Kay, Huber, Michael, Rex, Elizabeth, Coe, Kevin J, Wu, JieJun, Seierstad, Mark, Bembenek, Scott D, Leonard, Kristi A, Lebsack, Alec D, Venable, Jennifer D, Edwards, James P
Published in ACS medicinal chemistry letters (13.05.2021)
Published in ACS medicinal chemistry letters (13.05.2021)
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Synthesis and SAR of pyridazinone-substituted phenylalanine amide α4 integrin antagonists
YONG GONG, BARBAY, J. Kent, KIMBALL, Edward S, SANTULLI, Rosemary J, FISHER, M. Carolyn, DYATKIN, Alexey B, MISKOWSKI, Tamara A, HORNBY, Pamela J, WEI HE
Published in Bioorganic & medicinal chemistry letters (15.02.2008)
Published in Bioorganic & medicinal chemistry letters (15.02.2008)
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Substituted thieno[2,3-d]pyrimidines as adenosine A2A receptor antagonists
Shook, Brian C., Chakravarty, Devraj, Barbay, J. Kent, Wang, Aihua, Leonard, Kristi, Alford, Vernon, Powell, Mark T., Rassnick, Stefanie, Scannevin, Robert H., Carroll, Karen, Wallace, Nathaniel, Crooke, Jeffrey, Ault, Mark, Lampron, Lisa, Westover, Lori, Rhodes, Kenneth, Jackson, Paul F.
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
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Discovery and optimization of a series of small-molecule allosteric inhibitors of MALT1 protease
Lu, Tianbao, Connolly, Peter J., Philippar, Ulrike, Sun, Weimei, Cummings, Maxwell D., Barbay, Kent, Gys, Luc, Van Nuffel, Luc, Austin, Nigel, Bekkers, Mariette, Shen, Fang, Cai, Ann, Attar, Ricardo, Meerpoel, Lieven, Edwards, James
Published in Bioorganic & medicinal chemistry letters (01.12.2019)
Published in Bioorganic & medicinal chemistry letters (01.12.2019)
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Design and Characterization of Optimized Adenosine A2A/A1 Receptor Antagonists for the Treatment of Parkinson's Disease
Shook, Brian C, Rassnick, Stefanie, Wallace, Nathaniel, Crooke, Jeffrey, Ault, Mark, Chakravarty, Devraj, Barbay, J. Kent, Wang, Aihua, Powell, Mark T, Leonard, Kristi, Alford, Vernon, Scannevin, Robert H, Carroll, Karen, Lampron, Lisa, Westover, Lori, Lim, Heng-Keang, Russell, Ronald, Branum, Shawn, Wells, Kenneth M, Damon, Sandra, Youells, Scott, Li, Xun, Beauchamp, Derek A, Rhodes, Kenneth, Jackson, Paul F
Published in Journal of medicinal chemistry (09.02.2012)
Published in Journal of medicinal chemistry (09.02.2012)
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Optimization of arylindenopyrimidines as potent adenosine A(2A)/A(1) antagonists
Shook, Brian C, Rassnick, Stefanie, Chakravarty, Devraj, Wallace, Nathaniel, Ault, Mark, Crooke, Jeffrey, Barbay, J Kent, Wang, Aihua, Leonard, Kristi, Powell, Mark T, Alford, Vernon, Hall, Daniel, Rupert, Kenneth C, Heintzelman, Geoffrey R, Hansen, Kristen, Bullington, James L, Scannevin, Robert H, Carroll, Karen, Lampron, Lisa, Westover, Lori, Russell, Ronald, Branum, Shawn, Wells, Kenneth, Damon, Sandra, Youells, Scott, Beauchamp, Derek, Li, Xun, Rhodes, Kenneth, Jackson, Paul F
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
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HETEROARYL LINKED QUINOLINYL MODULATORS OF RORΓT
KREUTTER KEVIN D, VENKATESAN HARIHARAN, LEONARD KRISTI A, NISHIMURA RACHEL, BARBAY KENT, WOODS CRAIG R, EDWARDS JAMES P, XUE XIAOHUA, FOURIE ANNE, CUMMINGS MAXWELL D, URBANSKI MAUD, MAHAROOF UMAR, WANG AIHUA, KUMMER DAVID A, WOLIN RONALD L
Year of Publication 20.06.2016
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Year of Publication 20.06.2016
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ALKYL LINKED QUINOLINYL MODULATORS OF RORYT
KREUTTER KEVIN D, VENKATESAN HARIHARAN, LEONARD KRISTI A, NISHIMURA RACHEL, BARBAY KENT, WOODS CRAIG R, EDWARDS JAMES P, XUE XIAOHUA, FOURIE ANNE, CUMMINGS MAXWELL D, URBANSKI MAUD, MAHAROOF UMAR, WANG AIHUA, KUMMER DAVID A, WOLIN RONALD L
Year of Publication 17.06.2016
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Year of Publication 17.06.2016
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QUINOLINYL MODULATORS OF RORYT
MCCLURE KELLY, KREUTTER KEVIN D, VENKATESAN HARIHARAN, LEONARD KRISTI A, NISHIMURA RACHEL, BARBAY KENT, WOODS CRAIG R, EDWARDS JAMES P, XUE XIAOHUA, FOURIE ANNE, TANIS VIRGINIA, CUMMINGS MAXWELL D, URBANSKI MAUD, MAHAROOF UMAR, WANG AIHUA, KUMMER DAVID A, WOLIN RONALD L
Year of Publication 15.06.2016
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Year of Publication 15.06.2016
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PHENYL LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T
KREUTTER KEVIN D, VENKATESAN HARIHARAN, LEONARD KRISTI A, NISHIMURA RACHEL, BARBAY KENT, WOODS CRAIG R, EDWARDS JAMES P, XUE XIAOHUA, FOURIE ANNE, CUMMINGS MAXWELL D, URBANSKI MAUD, MAHAROOF UMAR, WANG AIHUA, KUMMER DAVID A, WOLIN RONALD L
Year of Publication 15.06.2016
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Year of Publication 15.06.2016
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SECONDARY ALCOHOL QUINOLINYL MODULATORS OF RORYT
KREUTTER KEVIN D, VENKATESAN HARIHARAN, LEONARD KRISTI A, NISHIMURA RACHEL, BARBAY KENT, WOODS CRAIG R, EDWARDS JAMES P, XUE XIAOHUA, FOURIE ANNE, CUMMINGS MAXWELL D, URBANSKI MAUD, MAHAROOF UMAR, WANG AIHUA, KUMMER DAVID A, WOLIN RONALD L
Year of Publication 15.06.2016
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Year of Publication 15.06.2016
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HETEROARYL LINKED QUINOLINYL MODULATORS OF RORΓT
KREUTTER KEVIN D, VENKATESAN HARIHARAN, LEONARD KRISTI A, NISHIMURA RACHEL, BARBAY KENT, WOODS CRAIG R, EDWARDS JAMES P, XUE XIAOHUA, FOURIE ANNE, URBANSKI MAUD, MAHAROOF UMAR, WANG AIHUA, KUMMER DAVID A, WOLIN RONALD L
Year of Publication 24.06.2015
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Year of Publication 24.06.2015
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PHENYL LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T
KREUTTER KEVIN D, VENKATESAN HARIHARAN, MIRZADEGAN TARANEH, LEONARD KRISTI A, NISHIMURA RACHEL, BARBAY KENT, WOODS CRAIG R, EDWARDS JAMES P, XUE XIAOHUA, FOURIE ANNE, URBANSKI MAUD, MAHAROOF UMAR, WANG AIHUA, KUMMER DAVID A, WOLIN RONALD L, GANAMET KELLY LYNN
Year of Publication 24.06.2015
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Year of Publication 24.06.2015
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METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T
KREUTTER KEVIN D, VENKATESAN HARIHARAN, LEONARD KRISTI A, NISHIMURA RACHEL, BARBAY KENT, WOODS CRAIG R, EDWARDS JAMES P, XUE XIAOHUA, FOURIE ANNE, URBANSKI MAUD, MAHAROOF UMAR, PIERCE JOAN, WANG AIHUA, KUMMER DAVID A, WOLIN RONALD L, GOLDBERG STEVEN
Year of Publication 24.06.2015
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Year of Publication 24.06.2015
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Synthesis and SAR of pyridazinone-substituted phenylalanine amide α 4 integrin antagonists
Gong, Yong, Kent Barbay, J., Kimball, Edward S., Santulli, Rosemary J., Carolyn Fisher, M., Dyatkin, Alexey B., Miskowski, Tamara A., Hornby, Pamela J., He, Wei
Published in Bioorganic & medicinal chemistry letters (2008)
Published in Bioorganic & medicinal chemistry letters (2008)
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