A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy
Ronan, Baptiste, Flamand, Odile, Vescovi, Lionel, Dureuil, Christine, Durand, Laurence, Fassy, Florence, Bachelot, Marie-France, Lamberton, Annabelle, Mathieu, Magali, Bertrand, Thomas, Marquette, Jean-Pierre, El-Ahmad, Youssef, Filoche-Romme, Bruno, Schio, Laurent, Garcia-Echeverria, Carlos, Goulaouic, Hélène, Pasquier, Benoit
Published in Nature chemical biology (01.12.2014)
Published in Nature chemical biology (01.12.2014)
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Journal Article
From PtCl2- and Acid-Catalyzed to Uncatalyzed Cycloisomerization of 2-Propargyl Anilines: Access to Functionalized Indoles
Cariou, Kevin, Ronan, Baptiste, Mignani, Serge, Fensterbank, Louis, Malacria, Max
Published in Angewandte Chemie International Edition (05.03.2007)
Published in Angewandte Chemie International Edition (05.03.2007)
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Journal Article
Discovery of (2S)‑8-[(3R)‑3-Methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro‑2H‑pyrimido[1,2‑a]pyrimidin-6-one: A Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors
Pasquier, Benoit, El-Ahmad, Youssef, Filoche-Rommé, Bruno, Dureuil, Christine, Fassy, Florence, Abecassis, Pierre-Yves, Mathieu, Magali, Bertrand, Thomas, Benard, Tsiala, Barrière, Cédric, El Batti, Samira, Letallec, Jean-Philippe, Sonnefraud, Véronique, Brollo, Maurice, Delbarre, Laurence, Loyau, Véronique, Pilorge, Fabienne, Bertin, Luc, Richepin, Patrick, Arigon, Jérôme, Labrosse, Jean-Robert, Clément, Jacques, Durand, Florence, Combet, Romain, Perraut, Pierre, Leroy, Vincent, Gay, Frédéric, Lefrançois, Dominique, Bretin, François, Marquette, Jean-Pierre, Michot, Nadine, Caron, Anne, Castell, Christelle, Schio, Laurent, McCort, Gary, Goulaouic, Hélène, Garcia-Echeverria, Carlos, Ronan, Baptiste
Published in Journal of medicinal chemistry (08.01.2015)
Published in Journal of medicinal chemistry (08.01.2015)
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Journal Article
Discovery of (2 S )-8-[(3 R )-3-Methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro-2 H -pyrimido[1,2- a ]pyrimidin-6-one: A Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors
Pasquier, Benoit, El-Ahmad, Youssef, Filoche-Rommé, Bruno, Dureuil, Christine, Fassy, Florence, Abecassis, Pierre-Yves, Mathieu, Magali, Bertrand, Thomas, Benard, Tsiala, Barrière, Cédric, El Batti, Samira, Letallec, Jean-Philippe, Sonnefraud, Véronique, Brollo, Maurice, Delbarre, Laurence, Loyau, Véronique, Pilorge, Fabienne, Bertin, Luc, Richepin, Patrick, Arigon, Jérôme, Labrosse, Jean-Robert, Clément, Jacques, Durand, Florence, Combet, Romain, Perraut, Pierre, Leroy, Vincent, Gay, Frédéric, Lefrançois, Dominique, Bretin, François, Marquette, Jean-Pierre, Michot, Nadine, Caron, Anne, Castell, Christelle, Schio, Laurent, McCort, Gary, Goulaouic, Hélène, Garcia-Echeverria, Carlos, Ronan, Baptiste
Published in Journal of medicinal chemistry (08.01.2015)
Published in Journal of medicinal chemistry (08.01.2015)
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Journal Article
Abstract 3070: Discovery of novel potent allele-selective KRAS-G12C covalent inhibitors stemming from DNA-encoded library
McCort, Gary, Arrebola, Rosalia, Calvet, Loreley, Ronan, Baptiste, Vergne, Fabrice, Duffieux, Francis, Rak, Alexey, Meaux, Isabelle, Papin, David, Fassy, Florence, Delorme, Cecile, Matthieu, Magali, Nicolas, Jean-Paul, Marcireau, Christophe, Steier, Valerie, Abecassis, Pierre-Yves, Czepczor, Valerie, Thomson, Heather A., Hupp, Christopher D., Guilinger, J.P., Zhang, Ying, Keefe, Anthony D., Cuozzo, John W., Liu, Julie, Debussche, Laurent
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
From PtCl 2 ‐ and Acid‐Catalyzed to Uncatalyzed Cycloisomerization of 2‐Propargyl Anilines: Access to Functionalized Indoles
Cariou, Kevin, Ronan, Baptiste, Mignani, Serge, Fensterbank, Louis, Malacria, Max
Published in Angewandte Chemie International Edition (05.03.2007)
Published in Angewandte Chemie International Edition (05.03.2007)
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Journal Article
PYRIDAZINE COMPOUNDS, THEIR PREPARATION, AND THEIR THERAPEUTIC USES
Petit, Fréderic, Terrier, Corinne, LETALLEC, Jean-Philippe, Ronan, Baptiste, Marguet, Franck
Year of Publication 31.10.2024
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Year of Publication 31.10.2024
Patent
PYRIDAZINE COMPOUNDS, THEIR PREPARATION, AND THEIR THERAPEUTIC USES
RONAN, Baptiste, PETIT, Fréderic, LETALLEC, Jean-Philippe, TERRIER, Corinne, MARGUET, Franck
Year of Publication 19.09.2024
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Year of Publication 19.09.2024
Patent
Preparation of 14,36-didehydro pristinamycins IIs
Ronan, Baptiste, Bacqué, Eric, Barrière, Jean-Claude, Sablé, Serge
Published in Tetrahedron (14.04.2003)
Published in Tetrahedron (14.04.2003)
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Journal Article
2,3-dihydro-1h-imidazo{1,2-a}pyrimidin-5-one and this 1,2,3,4-tetrahydropyrimido{1,2-a}pyrimidin-6-one derivatives comprising a substituted morpholine, preparation thereof and pharmaceutical use thereof
Brollo, Maurice, Marciniak, Gilbert, El-Ahmad, Youssef, Vivet, Bertrand, Letallec, Jean-Philippe, Ronan, Baptiste, Filoche-Romme, Bruno
Year of Publication 29.08.2023
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Year of Publication 29.08.2023
Patent
derivados de 6-(6-0-ciclo alquil ou 6-nh-ciclo alquil-triazolo piridazina sulfanil) benzotiazóis e benzimadazóis: preparo, aplicação como medicamentos e utilização como inibidores de met
Conception Nemecek, Eric Bacque, Baptiste Ronan, Antonio Ugolini, Sylvie Wentzler, Dominique Damour (Falecido)
Year of Publication 24.09.2019
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Year of Publication 24.09.2019
Patent
Design and synthesis of a prototype model antagonist of tachykinin NK-2 receptor
Hanessian, Stephen, Ronan, Baptiste, Laoui, Abdel
Published in Bioorganic & medicinal chemistry letters (09.06.1994)
Published in Bioorganic & medicinal chemistry letters (09.06.1994)
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Journal Article
PYRIMIDINONE DERIVATIVES AS ANTIMALARIAL AGENTS
RONAN, Baptiste, MUZET, Nicolas, FILOCHE-ROMME, Bruno, MARCINIAK, Gilbert, EL-AHMAD, Youssef, VIVET, Bertrand, GANZHORM, Axel, ZERR, Véronique
Year of Publication 17.06.2020
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Year of Publication 17.06.2020
Patent
Novel 2,3-Dihydro-1h-imidazo{1,2-a}pyrimidin-5-one and this 1,2,3,4-tetrahydropyrimido{1,2-a}pyrimidin-6-one Derivatives Comprising a Substituted Morpholine, Preparation Thereof and Pharmaceutical Use Thereof
Brollo, Maurice, Marciniak, Gilbert, El-Ahmad, Youssef, Vivet, Bertrand, Letallec, Jean-Philippe, Ronan, Baptiste, Filoche-Romme, Bruno
Year of Publication 26.09.2019
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Year of Publication 26.09.2019
Patent
2,3-dihydro-1H-imidazo{1,2-a}pyrimidin-5-one and this 1,2,3,4-tetrahydropyrimido{1,2-a}pyrimidin-6-one derivatives comprising a substituted morpholine, preparation thereof and pharmaceutical use thereof
Brollo, Maurice, Marciniak, Gilbert, El-Ahmad, Youssef, Vivet, Bertrand, Letallec, Jean-Philippe, Ronan, Baptiste, Filoche-Romme, Bruno
Year of Publication 09.04.2019
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Year of Publication 09.04.2019
Patent