A phase I dose-escalation study of enzalutamide in combination with the AKT inhibitor AZD5363 (capivasertib) in patients with metastatic castration-resistant prostate cancer
Kolinsky, M.P., Rescigno, P., Bianchini, D., Zafeiriou, Z., Mehra, N., Mateo, J., Michalarea, V., Riisnaes, R., Crespo, M., Figueiredo, I., Miranda, S., Nava Rodrigues, D., Flohr, P., Tunariu, N., Banerji, U., Ruddle, R., Sharp, A., Welti, J., Lambros, M., Carreira, S., Raynaud, F.I., Swales, K.E., Plymate, S., Luo, J., Tovey, H., Porta, N., Slade, R., Leonard, L., Hall, E., de Bono, J.S.
Published in Annals of oncology (01.05.2020)
Published in Annals of oncology (01.05.2020)
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Safety, tolerability, pharmacokinetics and pharmacodynamics of AZD8055 in advanced solid tumours and lymphoma
Naing, A, Aghajanian, C, Raymond, E, Olmos, D, Schwartz, G, Oelmann, E, Grinsted, L, Burke, W, Taylor, R, Kaye, S, Kurzrock, R, Banerji, U
Published in British journal of cancer (25.09.2012)
Published in British journal of cancer (25.09.2012)
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PATRIOT: A phase I study to assess the tolerability, safety and biological effects of a specific ataxia telangiectasia and Rad3-related (ATR) inhibitor (AZD6738) as a single agent and in combination with palliative radiation therapy in patients with solid tumours
Dillon, M.T., Boylan, Z., Smith, D., Guevara, J., Mohammed, K., Peckitt, C., Saunders, M., Banerji, U., Clack, G., Smith, S.A., Spicer, J.F., Forster, M.D., Harrington, K.J.
Published in Clinical and translational radiation oncology (01.08.2018)
Published in Clinical and translational radiation oncology (01.08.2018)
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The paradox-breaking panRAF plus SRC family kinase inhibitor, CCT3833, is effective in mutant KRAS-driven cancers
Saturno, G., Lopes, F., Niculescu-Duvaz, I., Niculescu-Duvaz, D., Zambon, A., Davies, L., Johnson, L., Preece, N., Lee, R., Viros, A., Holovanchuk, D., Pedersen, M., McLeary, R., Lorigan, P., Dhomen, N., Fisher, C., Banerji, U., Dean, E., Krebs, M.G., Gore, M., Larkin, J., Marais, R., Springer, C.
Published in Annals of oncology (01.02.2021)
Published in Annals of oncology (01.02.2021)
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Clinical benefit in Phase-I trials of novel molecularly targeted agents: does dose matter?
Postel-Vinay, S, Arkenau, H-T, Olmos, D, Ang, J, Barriuso, J, Ashley, S, Banerji, U, De-Bono, J, Judson, I, Kaye, S
Published in British journal of cancer (05.05.2009)
Published in British journal of cancer (05.05.2009)
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Complications of hyperglycaemia with PI3K–AKT–mTOR inhibitors in patients with advanced solid tumours on Phase I clinical trials
Geuna, E, Roda, D, Rafii, S, Jimenez, B, Capelan, M, Rihawi, K, Montemurro, F, Yap, T A, Kaye, S B, De Bono, J S, Molife, L R, Banerji, U
Published in British journal of cancer (01.12.2015)
Published in British journal of cancer (01.12.2015)
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Vistusertib (dual m-TORC1/2 inhibitor) in combination with paclitaxel in patients with high-grade serous ovarian and squamous non-small-cell lung cancer
Basu, B., Krebs, M.G., Sundar, R., Wilson, R.H., Spicer, J., Jones, R., Brada, M., Talbot, D.C., Steele, N., Ingles Garces, A.H., Brugger, W., Harrington, E.A., Evans, J., Hall, E., Tovey, H., de Oliveira, F.M., Carreira, S., Swales, K., Ruddle, R., Raynaud, F.I., Purchase, B., Dawes, J.C., Parmar, M., Turner, A.J., Tunariu, N., Banerjee, S., de Bono, J.S., Banerji, U.
Published in Annals of oncology (01.09.2018)
Published in Annals of oncology (01.09.2018)
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Phase I trial outcomes in older patients with advanced solid tumours
Khan, K H, Yap, T A, Ring, A, Molife, L R, Bodla, S, Thomas, K, Zivi, A, Smith, A, Judson, I, Banerji, U, de Bono, J S, Kaye, S B
Published in British journal of cancer (02.02.2016)
Published in British journal of cancer (02.02.2016)
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A first-in-human phase I study of the PD-1 inhibitor, retifanlimab (INCMGA00012), in patients with advanced solid tumors (POD1UM-101)
Lakhani, N., Cosman, R., Banerji, U., Rasco, D., Tomaszewska-Kiecana, M., Garralda, E., Kornacki, D., Li, J., Tian, C., Bourayou, N., Powderly, J.
Published in ESMO open (01.04.2024)
Published in ESMO open (01.04.2024)
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KRAS mutant and RAS/BRAF wild type colorectal cancer cells exhibit differences in the rewiring of signal transduction that can impact on future therapeutic strategies
Georgiou, A., Stewart, A., Thavasu, P., Coker, E.A., Poelsterl, S., Al-Lazikani, B., Cunningham, D., Whittaker, S., Banerji, U.
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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A phase I/II trial of AT9283, a selective inhibitor of aurora kinase in children with relapsed or refractory acute leukemia: challenges to run early phase clinical trials for children with leukemia
Vormoor, B., Veal, G. J., Griffin, M. J., Boddy, A. V., Irving, J., Minto, L., Case, M., Banerji, U., Swales, K. E., Tall, J. R., Moore, A. S., Toguchi, M., Acton, G., Dyer, K., Schwab, C., Harrison, C. J., Grainger, J. D., Lancaster, D., Kearns, P., Hargrave, D., Vormoor, J.
Published in Pediatric blood & cancer (01.06.2017)
Published in Pediatric blood & cancer (01.06.2017)
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AKT inhibition synergistically enhances growth-inhibitory effects of gefitinib and increases apoptosis in non-small cell lung cancer cell lines
Puglisi, M, Thavasu, P, Stewart, A, de Bono, J.S, O’Brien, M.E.R, Popat, S, Bhosle, J, Banerji, U
Published in Lung cancer (Amsterdam, Netherlands) (01.08.2014)
Published in Lung cancer (Amsterdam, Netherlands) (01.08.2014)
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Hsp90 inhibitors in the clinic
Pacey, S, Banerji, U, Judson, I, Workman, P
Published in Handbook of experimental pharmacology (2006)
Published in Handbook of experimental pharmacology (2006)
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333 Phase I dose-escalation trial with the DNA-alkylating anti-HER2 antibody-drug conjugate SYD985
Van Herpen, C.M, Banerji, U, Mommers, E.C, Koper, N.P, Goedings, P, Lopez, J, Awada, A, Fiebrich, H.B, Aftimos, P.G
Published in European journal of cancer (1990) (01.09.2015)
Published in European journal of cancer (1990) (01.09.2015)
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Clinical Outcome of Patients with Advanced Biliary Tract Cancer in a Dedicated Phase I Unit
Sundar, R., Custodio, A., Petruckevich, A., Chénard-Poirier, M., Ameratunga, M., Collins, D., Lim, J., Kaye, S.B., Tunariu, N., Banerji, U., de Bono, J., Lopez, J.
Published in Clinical oncology (Royal College of Radiologists (Great Britain)) (01.03.2018)
Published in Clinical oncology (Royal College of Radiologists (Great Britain)) (01.03.2018)
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Association of creatine kinase and skin toxicity in phase I trials of anticancer agents
Moreno Garcia, V, Thavasu, P, Blanco Codesido, M, Molife, L R, Vitfell Pedersen, J, Puglisi, M, Basu, B, Shah, K, Iqbal, J, de Bono, J S, Kaye, S B, Banerji, U
Published in British journal of cancer (20.11.2012)
Published in British journal of cancer (20.11.2012)
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A phase I II trial of sorafenib and infliximab in advanced renal cell carcinoma
Larkin, J M G, Ferguson, T R, Pickering, L M, Edmonds, K, James, M G, Thomas, K, Banerji, U, Berns, B, de Boer, C, Gore, M E
Published in British journal of cancer (12.10.2010)
Published in British journal of cancer (12.10.2010)
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Defining the risk of toxicity in phase I oncology trials of novel molecularly targeted agents: a single centre experience
Molife, L.R., Alam, S., Olmos, D., Puglisi, M., Shah, K., Fehrmann, R., Trani, L., Tjokrowidjaja, A., de Bono, J.S., Banerji, U., Kaye, S.B.
Published in Annals of oncology (01.08.2012)
Published in Annals of oncology (01.08.2012)
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