Mechanism-Specific Pharmacodynamics of a Novel Complex-I Inhibitor Quantified by Imaging Reversal of Consumptive Hypoxia with [ 18 F]FAZA PET In Vivo
Gammon, Seth T, Pisaneschi, Federica, Bandi, Madhavi L, Smith, Melinda G, Sun, Yuting, Rao, Yi, Muller, Florian, Wong, Franklin, De Groot, John, Ackroyd, Jeffrey, Mawlawi, Osama, Davies, Michael A, Gopal, Y N Vashisht, Di Francesco, M Emilia, Marszalek, Joseph R, Dewhirst, Mark, Piwnica-Worms, David
Published in Cells (Basel, Switzerland) (21.11.2019)
Published in Cells (Basel, Switzerland) (21.11.2019)
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Journal Article
BET Bromodomain Inhibition Suppresses Human T Cell Function
Georgiev, Peter, Wang, Yun, Muise, Eric S, Bandi, Madhavi L, Blumenschein, Wendy, Sathe, Manjiri, Pinheiro, Elaine M, Shumway, Stuart D
Published in ImmunoHorizons (11.07.2019)
Published in ImmunoHorizons (11.07.2019)
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Abstract 1655: Discovery and development of IACS-010759, a novel inhibitor of Complex I currently in phase I studies to exploit oxidative phosphorylation dependency in acute myeloid leukemia and solid tumors
Francesco, Maria Emilia Di, Marszalek, Joseph R., McAfoos, Timothy, Carroll, Christopher L., Kang, Zhijun, Liu, Gang, Theroff, Jay P., Bardenhager, Jennifer P., Bandi, Madhavi L., Molina, Jennifer R., Gera, Sonal, Protopopova, Marina, Sun, Yuting, Do, Mary K. Geck, Feng, Ningping, Gay, Jason P., Muller, Florian, Konopleva, Marina, Meric-Bernstam, Funda, Toniatti, Carlo, Heffernan, Timothy P., Draetta, Giulio F., Jones, Philip
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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AT9283, a Small Molecule Multi-Targeted Kinase Inhibitor with Potent Activity Against Aurora Kinase and STAT3 In Combination with Lenalidomide Results In Synergistic Anti-Myeloma Activity
Santo, Loredana, Hideshima, Teru, Cirstea, Diana, Bandi, Madhavi L, Nelson, Erik A, Ikeda, Hiroshi, Vallet, Sonia, Pozzi, Samantha, Patel, Kishan, Gorgun, Gullu, Mimura, Naoya, Fabre, Claire, Hu, Yiguo, Chauhan, Dharminder, Squires, Matthew S, Munshi, Nikhil C., Anderson, Kenneth C., Raje, Noopur
Published in Blood (19.11.2010)
Published in Blood (19.11.2010)
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Abstract 2530: Antimyeloma activity of a small molecule multi-targeted kinase inhibitor, AT9283, via potent aurora kinase and STAT3 inhibition
Santo, Loredana, Hideshima, Teru, Cirstea, Diana, Nelson, Erik A., Bandi, Madhavi L., Gorgun, Gullu, Vallet, Sonia, Pozzi, Samantha, Patel, Kishan, Ikeda, Hiroshi, Perrone, Giulia, Hu, Yiguo, Chauhan, Dharminder, Squires, Matthew, Munshi, Nikhil C., Anderson, Kenneth C., Raje, Noopur
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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